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Published in: BMC Public Health 3/2013

Open Access 01-09-2013 | Review

Systematic review of strategies to increase use of oral rehydration solution at the household level

Authors: Lindsey M Lenters, Jai K Das, Zulfiqar A Bhutta

Published in: BMC Public Health | Special Issue 3/2013

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Abstract

Background

Diarrhea is one of the major causes of death in children under five years of age, disproportionately affecting children in low- and middle-income countries. Treatment of diarrhea with oral rehydration solution addresses dehydration and reduces diarrhea related deaths. The World Health Organization Programme for the Control of Diarrhoeal Disease began in 1978 and while global ORS access rates have improved substantially over the past forty years, rates of ORS use have stagnated. Investigation is required to understand which interventions are effective in promoting the use of ORS, and where there are gaps in the literature.

Methods

We conducted a systematic search of peer-reviewed and grey literature and included interventions to promote the use of ORS for the treatment of acute diarrhea in children under 6 years. We used a standardized grading format based on the Child Health Epidemiology Research Group guidelines and performed meta-analysis for all categories with more than one data point.

Results

We identified 19 studies for abstraction. For co-promotion of zinc and ORS, mothers in the intervention group were 1.82 (95% CI 1.17, 2.85) times more likely to use ORS to treat their child’s diarrhea episode than mothers in the comparison group. Meta-analysis of ORS social marketing and mass media strategies indicates that mothers exposed to messages were 2.05 (95% CI, 0.78, 5.42) times more likely to use ORS to treat their child’s diarrhea episode than unexposed mothers. However, this is not statistically significant. Both meta-analysis had significant heterogeneity and were graded as moderate/low and low quality, respectively.

Conclusions

We found few studies of interventions to promote the use of ORS; many categories of interventions had only one study. While there are some promising results, this analysis reinforces the need for further investigation into approaches to increasing ORS use.
Appendix
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Literature
1.
go back to reference Liu L, Johnson HL, Cousens S, Perin J, Scott S, Lawn JE, Rudan I, Campbell H, Cibulskis R, Li M, Mathers C, Black RE: Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet. 2012, 379: 2151-61. 10.1016/S0140-6736(12)60560-1.CrossRefPubMed Liu L, Johnson HL, Cousens S, Perin J, Scott S, Lawn JE, Rudan I, Campbell H, Cibulskis R, Li M, Mathers C, Black RE: Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet. 2012, 379: 2151-61. 10.1016/S0140-6736(12)60560-1.CrossRefPubMed
2.
go back to reference Santosham M, Chandran A, Fitzwater S, Fischer-walker C, Baqui AH, Black R: Progress and barriers for the control of diarrhoeal disease. Lancet. 2010, 376: 63-67. 10.1016/S0140-6736(10)60356-X.CrossRefPubMed Santosham M, Chandran A, Fitzwater S, Fischer-walker C, Baqui AH, Black R: Progress and barriers for the control of diarrhoeal disease. Lancet. 2010, 376: 63-67. 10.1016/S0140-6736(10)60356-X.CrossRefPubMed
3.
go back to reference Bhattacharya SK: Progress in the control and prevention of diarrhoeal diseases since Independence. Natl Med J India. 2003, 16 Suppl 2: 15-19.PubMed Bhattacharya SK: Progress in the control and prevention of diarrhoeal diseases since Independence. Natl Med J India. 2003, 16 Suppl 2: 15-19.PubMed
4.
go back to reference Munos MK, Walker CLF, Black RE: The effect of oral rehydration solution and recommended home fluids on diarrhoea mortality. International journal of epidemiology. 2010, 39 (Suppl 1): i75-87.PubMedCentralCrossRefPubMed Munos MK, Walker CLF, Black RE: The effect of oral rehydration solution and recommended home fluids on diarrhoea mortality. International journal of epidemiology. 2010, 39 (Suppl 1): i75-87.PubMedCentralCrossRefPubMed
5.
go back to reference Claeson M, H MM: Global Progress in the Control of Diarrheal Diseases. Pediatr Infect Dis J. 1990, 9: 345-55. 10.1097/00006454-199005000-00008.CrossRefPubMed Claeson M, H MM: Global Progress in the Control of Diarrheal Diseases. Pediatr Infect Dis J. 1990, 9: 345-55. 10.1097/00006454-199005000-00008.CrossRefPubMed
6.
go back to reference Ram PK, Choi M, Blum LS, Wamae AW, Mintz ED, Bartlett AV: Declines in case management of diarrhoea among children less than five years old (letter). Bull World Health Organ. 2008, 86: E-F.PubMedCentralCrossRefPubMed Ram PK, Choi M, Blum LS, Wamae AW, Mintz ED, Bartlett AV: Declines in case management of diarrhoea among children less than five years old (letter). Bull World Health Organ. 2008, 86: E-F.PubMedCentralCrossRefPubMed
7.
go back to reference Sabot O, Schroder K, Yamey G, Montagu D: Scaling up oral rehydration salts and zinc for the treatment of diarrhoea. BMJ. 2012, 344: e940-10.1136/bmj.e940.CrossRefPubMed Sabot O, Schroder K, Yamey G, Montagu D: Scaling up oral rehydration salts and zinc for the treatment of diarrhoea. BMJ. 2012, 344: e940-10.1136/bmj.e940.CrossRefPubMed
8.
go back to reference Boschi-Pinto C, Bahl R, Martines J: Limited Progress in Increasing Coverage of Neonatal and Child-health Interventions in Africa and Asia. J Health Popul Nutr. 2009, 27: 755-762.PubMedCentralPubMed Boschi-Pinto C, Bahl R, Martines J: Limited Progress in Increasing Coverage of Neonatal and Child-health Interventions in Africa and Asia. J Health Popul Nutr. 2009, 27: 755-762.PubMedCentralPubMed
9.
go back to reference Sengupta PG, Mondal SK, Ghosh S, Gupta DN, Sikder SN, Sircar BK: Review on development and community implementation of oral rehydration therapy. Indian journal of public health. 1994, 38: 50-57.PubMed Sengupta PG, Mondal SK, Ghosh S, Gupta DN, Sikder SN, Sircar BK: Review on development and community implementation of oral rehydration therapy. Indian journal of public health. 1994, 38: 50-57.PubMed
10.
go back to reference Walker N, Fischer-Walker C, Bryce J, Bahl R, Cousens S: Standards for CHERG reviews of intervention effects on child survival. International journal of epidemiology. 2010, 39 (Suppl 1): i21-31.PubMedCentralCrossRefPubMed Walker N, Fischer-Walker C, Bryce J, Bahl R, Cousens S: Standards for CHERG reviews of intervention effects on child survival. International journal of epidemiology. 2010, 39 (Suppl 1): i21-31.PubMedCentralCrossRefPubMed
11.
go back to reference Winch PJ, Gilroy KE, Doumbia S, Patterson AE, Daou Z, Diawara A, Swedberg E, Black RE, Fontaine O, Mali Zinc Pilot Intervention Study Group: Operational issues and trends associated with the pilot introduction of zinc for childhood diarrhoea in Bougouni district, Mali. J Health Popul Nutr. 2008, 26: 151-162.PubMedCentralPubMed Winch PJ, Gilroy KE, Doumbia S, Patterson AE, Daou Z, Diawara A, Swedberg E, Black RE, Fontaine O, Mali Zinc Pilot Intervention Study Group: Operational issues and trends associated with the pilot introduction of zinc for childhood diarrhoea in Bougouni district, Mali. J Health Popul Nutr. 2008, 26: 151-162.PubMedCentralPubMed
12.
go back to reference Cambodian Red Cross: Integrated child health project activity and evaluation report III: Diarrhea control and diarrhea treatment kits. 2006 Cambodian Red Cross: Integrated child health project activity and evaluation report III: Diarrhea control and diarrhea treatment kits. 2006
13.
go back to reference Jinadu MK, Olusi SO, Alade OM, Ominiyi CL: Effectiveness of primary health-care nurses in the promotion of oral rehydration therapy in a rural area of Nigeria. International journal of nursing studies. 1988, 25: 185-90. 10.1016/0020-7489(88)90045-4.CrossRefPubMed Jinadu MK, Olusi SO, Alade OM, Ominiyi CL: Effectiveness of primary health-care nurses in the promotion of oral rehydration therapy in a rural area of Nigeria. International journal of nursing studies. 1988, 25: 185-90. 10.1016/0020-7489(88)90045-4.CrossRefPubMed
14.
go back to reference Jintaganont P, Stoeckel J, Butaras S: The impact of an oral rehydration therapy program in Southern Thailand. American journal of public health. 1988, 78: 1302-4. 10.2105/AJPH.78.10.1302.PubMedCentralCrossRefPubMed Jintaganont P, Stoeckel J, Butaras S: The impact of an oral rehydration therapy program in Southern Thailand. American journal of public health. 1988, 78: 1302-4. 10.2105/AJPH.78.10.1302.PubMedCentralCrossRefPubMed
15.
go back to reference Gutiérrez G, Tapia-Conyer R, Guiscafré H, Reyes H, Martínez H, Kumate J: Impact of oral rehydration and selected public health interventions on reduction of mortality from childhood diarrhoeal diseases in Mexico. Bulletin of the World Health Organization. 1996, 74: 189-97.PubMedCentralPubMed Gutiérrez G, Tapia-Conyer R, Guiscafré H, Reyes H, Martínez H, Kumate J: Impact of oral rehydration and selected public health interventions on reduction of mortality from childhood diarrhoeal diseases in Mexico. Bulletin of the World Health Organization. 1996, 74: 189-97.PubMedCentralPubMed
16.
go back to reference Baqui AH, Black RE, EA S, Y M, Zaman K, Begum N, Roess AA, Santosham M: Zinc Therapy for Diarrhea Increased the Use of Oral Rehydration Therapy and Reduced the Use of Antibiotics in Bangladeshi Children. J Health Popul Nutr. 2004, 22: 440-442.PubMed Baqui AH, Black RE, EA S, Y M, Zaman K, Begum N, Roess AA, Santosham M: Zinc Therapy for Diarrhea Increased the Use of Oral Rehydration Therapy and Reduced the Use of Antibiotics in Bangladeshi Children. J Health Popul Nutr. 2004, 22: 440-442.PubMed
17.
go back to reference Bhandari N, Mazumder S, Taneja S, Dube B, Agarwal RC, Mahalanabis D, Fontaine O, Black RE, Bhan MK: Effectiveness of zinc supplementation plus oral rehydration salts compared with oral rehydration salts alone as a treatment for acute diarrhea in a primary care setting: a cluster randomized trial. Pediatrics. 2008, 121: e1279-85. 10.1542/peds.2007-1939.CrossRefPubMed Bhandari N, Mazumder S, Taneja S, Dube B, Agarwal RC, Mahalanabis D, Fontaine O, Black RE, Bhan MK: Effectiveness of zinc supplementation plus oral rehydration salts compared with oral rehydration salts alone as a treatment for acute diarrhea in a primary care setting: a cluster randomized trial. Pediatrics. 2008, 121: e1279-85. 10.1542/peds.2007-1939.CrossRefPubMed
18.
go back to reference Awasthi S: Zinc supplementation in acute diarrhea is acceptable, does not interfere with oral rehydration, and reduces the use of other medications: a randomized trial in five countries. Journal of pediatric gastroenterology and nutrition. 2006, 42: 300-5.CrossRefPubMed Awasthi S: Zinc supplementation in acute diarrhea is acceptable, does not interfere with oral rehydration, and reduces the use of other medications: a randomized trial in five countries. Journal of pediatric gastroenterology and nutrition. 2006, 42: 300-5.CrossRefPubMed
19.
go back to reference Kassegne S, Kays MB, Nzohabonayo J: Evaluation of a social marketing intervention promoting oral rehydration salts in Burundi. BMC public health. 2011, 11: 155-10.1186/1471-2458-11-155.PubMedCentralCrossRefPubMed Kassegne S, Kays MB, Nzohabonayo J: Evaluation of a social marketing intervention promoting oral rehydration salts in Burundi. BMC public health. 2011, 11: 155-10.1186/1471-2458-11-155.PubMedCentralCrossRefPubMed
20.
go back to reference Rao KV, Mishra VK, Retherford RD: Knowledge and Use of Oral Rehydration Therapy for Childhood Diarrhoea in India: Effects of Exposure to Mass Media. 1998 Rao KV, Mishra VK, Retherford RD: Knowledge and Use of Oral Rehydration Therapy for Childhood Diarrhoea in India: Effects of Exposure to Mass Media. 1998
21.
go back to reference Population Services International: Malawi (2008) Maternal and Child Health TraC Study Evaluating Oral Rehydration Salts (ORS) and Hygiene for the Prevention of Diarrhea and Cholera among Caregivers of Children Under Five. 2009 Population Services International: Malawi (2008) Maternal and Child Health TraC Study Evaluating Oral Rehydration Salts (ORS) and Hygiene for the Prevention of Diarrhea and Cholera among Caregivers of Children Under Five. 2009
22.
go back to reference Pahwa S, Kumar GT, Toteja GS: Performance of a community-based health and nutrition-education intervention in the management of diarrhoea in a slum of Delhi, India. J Health Popul Nutr. 2010, 28: 553-559.PubMedCentralCrossRefPubMed Pahwa S, Kumar GT, Toteja GS: Performance of a community-based health and nutrition-education intervention in the management of diarrhoea in a slum of Delhi, India. J Health Popul Nutr. 2010, 28: 553-559.PubMedCentralCrossRefPubMed
23.
go back to reference Rahaman MM, Aziz KM, Patwari Y, Munshi MH: Diarrheal mortality in two Bangladeshi villages with and without community-based oral rehydration therapy. Lancet. 1979, 2: 809-812.CrossRefPubMed Rahaman MM, Aziz KM, Patwari Y, Munshi MH: Diarrheal mortality in two Bangladeshi villages with and without community-based oral rehydration therapy. Lancet. 1979, 2: 809-812.CrossRefPubMed
24.
go back to reference Kumar V, Kumar R, Datta N: Oral rehydration therapy in reducing diarrhea related mortality in rural India. Journal of diarrhoeal diseases research. 1987, 5: 159-164.PubMed Kumar V, Kumar R, Datta N: Oral rehydration therapy in reducing diarrhea related mortality in rural India. Journal of diarrhoeal diseases research. 1987, 5: 159-164.PubMed
25.
go back to reference MkNelly B, Dunford C: Impact of Credit with Education on Mothers and Their Young Children’s Nutrition: Lower Pra Rural Bank Credit with Education Program in Ghana. 1998 MkNelly B, Dunford C: Impact of Credit with Education on Mothers and Their Young Children’s Nutrition: Lower Pra Rural Bank Credit with Education Program in Ghana. 1998
26.
go back to reference Langsten RL, Kenneth H: Treatment of Childhood Diarrhea in Rural Egypt. Social Science and Medicine. 1995, 40: 989-1001. 10.1016/0277-9536(94)00163-N.CrossRefPubMed Langsten RL, Kenneth H: Treatment of Childhood Diarrhea in Rural Egypt. Social Science and Medicine. 1995, 40: 989-1001. 10.1016/0277-9536(94)00163-N.CrossRefPubMed
27.
go back to reference Victora CG, Black RE, Boerma JT, Bryce J: Measuring impact in the Millennium Development Goal era and beyond: a new approach to large-scale effectiveness evaluations. Lancet. 2011, 377: 85-95. 10.1016/S0140-6736(10)60810-0.CrossRefPubMed Victora CG, Black RE, Boerma JT, Bryce J: Measuring impact in the Millennium Development Goal era and beyond: a new approach to large-scale effectiveness evaluations. Lancet. 2011, 377: 85-95. 10.1016/S0140-6736(10)60810-0.CrossRefPubMed
28.
go back to reference Larson CP, Koehlmoos TP, Sack Da: Scaling up zinc treatment of childhood diarrhoea in Bangladesh: theoretical and practical considerations guiding the SUZY Project. Health policy and planning. 2011, 27: 102-14.CrossRefPubMed Larson CP, Koehlmoos TP, Sack Da: Scaling up zinc treatment of childhood diarrhoea in Bangladesh: theoretical and practical considerations guiding the SUZY Project. Health policy and planning. 2011, 27: 102-14.CrossRefPubMed
Metadata
Title
Systematic review of strategies to increase use of oral rehydration solution at the household level
Authors
Lindsey M Lenters
Jai K Das
Zulfiqar A Bhutta
Publication date
01-09-2013
Publisher
BioMed Central
Published in
BMC Public Health / Issue Special Issue 3/2013
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-13-S3-S28

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