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Published in: BMC Public Health 1/2011

Open Access 01-12-2011 | Research article

Can we use the pharmacy data to estimate the prevalence of chronic conditions? a comparison of multiple data sources

Authors: Francesco Chini, Patrizio Pezzotti, Letizia Orzella, Piero Borgia, Gabriella Guasticchi

Published in: BMC Public Health | Issue 1/2011

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Abstract

Background

The estimate of the prevalence of the most common chronic conditions (CCs) is calculated using direct methods such as prevalence surveys but also indirect methods using health administrative databases.
The aim of this study is to provide estimates prevalence of CCs in Lazio region of Italy (including Rome), using the drug prescription's database and to compare these estimates with those obtained using other health administrative databases.

Methods

Prevalence of CCs was estimated using pharmacy data (PD) using the Anathomical Therapeutic Chemical Classification System (ATC).
Prevalences estimate were compared with those estimated by hospital information system (HIS) using list of ICD9-CM diagnosis coding, registry of exempt patients from health care cost for pathology (REP) and national health survey performed by the Italian bureau of census (ISTAT).

Results

From the PD we identified 20 CCs. About one fourth of the population received a drug for treating a cardiovascular disease, 9% for treating a rheumatologic conditions.
The estimated prevalences using the PD were usually higher that those obtained with one of the other sources. Regarding the comparison with the ISTAT survey there was a good agreement for cardiovascular disease, diabetes and thyroid disorder whereas for rheumatologic conditions, chronic respiratory illnesses, migraine and Alzheimer's disease, the prevalence estimates were lower than those estimated by ISTAT survey. Estimates of prevalences derived by the HIS and by the REP were usually lower than those of the PD (but malignancies, chronic renal diseases).

Conclusion

Our study showed that PD can be used to provide reliable prevalence estimates of several CCs in the general population.
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Literature
2.
go back to reference Wiréhn AB, Karlsson HM, Carstensen JM: Estimating disease prevalence using a population-based administrative healthcare database. Scand J Public Health. 2007, 35 (4): 424-31. 10.1080/14034940701195230.CrossRefPubMed Wiréhn AB, Karlsson HM, Carstensen JM: Estimating disease prevalence using a population-based administrative healthcare database. Scand J Public Health. 2007, 35 (4): 424-31. 10.1080/14034940701195230.CrossRefPubMed
3.
go back to reference Corti MC, Guralnik JM, Sartori L, Baggio G, Manzato E, Pezzotti P, Barbato G, Zambon S, Ferrucci L, Minervini S, Musacchio E, Crepaldi G: The effect of cardiovascular and osteoarticular diseases on disability in older Italian men and women: rationale, design, and sample characteristics of the Progetto Veneto Anziani (PRO.V.A.) study. J Am Geriatr Soc. 2002, 50 (9): 1535-40. 10.1046/j.1532-5415.2002.50409.x.CrossRefPubMed Corti MC, Guralnik JM, Sartori L, Baggio G, Manzato E, Pezzotti P, Barbato G, Zambon S, Ferrucci L, Minervini S, Musacchio E, Crepaldi G: The effect of cardiovascular and osteoarticular diseases on disability in older Italian men and women: rationale, design, and sample characteristics of the Progetto Veneto Anziani (PRO.V.A.) study. J Am Geriatr Soc. 2002, 50 (9): 1535-40. 10.1046/j.1532-5415.2002.50409.x.CrossRefPubMed
4.
go back to reference The Italian Longitudinal Study on Aging working group: Prevalence of chronic diseases in older Italians: comparing self-reported and clinical diagnoses. Int J Epidemiol. 1997, 26: 995-1002.CrossRef The Italian Longitudinal Study on Aging working group: Prevalence of chronic diseases in older Italians: comparing self-reported and clinical diagnoses. Int J Epidemiol. 1997, 26: 995-1002.CrossRef
5.
go back to reference Cory S, Ussery-Hall A, Griffin-Blake S, Easton A, Vigeant J, Balluz L, Garvin W, Greenlund K: Centers for Disease Control and Prevention (CDC). Prevalence of selected risk behaviors and chronic diseases and conditions-steps communities, United States, 2006-2007. MMWR Surveill Summ. 2010, 24;59 (8): 1-37. Cory S, Ussery-Hall A, Griffin-Blake S, Easton A, Vigeant J, Balluz L, Garvin W, Greenlund K: Centers for Disease Control and Prevention (CDC). Prevalence of selected risk behaviors and chronic diseases and conditions-steps communities, United States, 2006-2007. MMWR Surveill Summ. 2010, 24;59 (8): 1-37.
6.
7.
go back to reference Cardo S, Agabiti N, Picconi O, Scarinci M, Papini P, Guasticchi G, Gentile D, Forastiere F, Arcà M, Volpe M, Perucci CA: The quality of medical records: a retrospective study in Lazio Region, Italy. Ann Ig. 2003, Italian, 15 (5): 433-42. Cardo S, Agabiti N, Picconi O, Scarinci M, Papini P, Guasticchi G, Gentile D, Forastiere F, Arcà M, Volpe M, Perucci CA: The quality of medical records: a retrospective study in Lazio Region, Italy. Ann Ig. 2003, Italian, 15 (5): 433-42.
8.
go back to reference Schoenman JA, Sutton JP, Elixhauser A, Love D: Understanding and enhancing the value of hospital discharge data. Med Care Res Rev. 2007, 64 (4): 449-68. 10.1177/1077558707301963.CrossRefPubMed Schoenman JA, Sutton JP, Elixhauser A, Love D: Understanding and enhancing the value of hospital discharge data. Med Care Res Rev. 2007, 64 (4): 449-68. 10.1177/1077558707301963.CrossRefPubMed
9.
go back to reference Fabiani L, Scatigna M, Panopoulou K, Sabatini A, Sessa E, Donato F, Marchi M: Health Search--Research Institute of the Italian Society of General Practice:the creation of a research database in general practice. Epidemiol Prev. 2004, Italian, 28 (3): 156-62. Fabiani L, Scatigna M, Panopoulou K, Sabatini A, Sessa E, Donato F, Marchi M: Health Search--Research Institute of the Italian Society of General Practice:the creation of a research database in general practice. Epidemiol Prev. 2004, Italian, 28 (3): 156-62.
10.
go back to reference Cricelli C, Mazzaglia G, Samani F, Marchi M, Sabatini A, Nardi R, Caputi AP: Prevalence estimates for chronic diseases in Italy: exploring the differences between self-report and primary care databases. J Public Health Med. 2003, 25 (3): 254-7. 10.1093/pubmed/fdg060.CrossRefPubMed Cricelli C, Mazzaglia G, Samani F, Marchi M, Sabatini A, Nardi R, Caputi AP: Prevalence estimates for chronic diseases in Italy: exploring the differences between self-report and primary care databases. J Public Health Med. 2003, 25 (3): 254-7. 10.1093/pubmed/fdg060.CrossRefPubMed
11.
go back to reference Von Korff M, Wagner EH, Saunders K: A chronic disease score from automated pharmacy data. Journal of Clinical Epidemiology. 1992, 45: 197-203. 10.1016/0895-4356(92)90016-G.CrossRefPubMed Von Korff M, Wagner EH, Saunders K: A chronic disease score from automated pharmacy data. Journal of Clinical Epidemiology. 1992, 45: 197-203. 10.1016/0895-4356(92)90016-G.CrossRefPubMed
12.
go back to reference Maio V, Yuen E, Rabinowitz C, Louis D, Jimbo M, Donatini A, Mall S, Taroni F: Using pharmacy data to identify those with chronic conditions in Emilia Romagna, Italy. J Health Serv Res Policy. 2005, 10 (4): 232-8. 10.1258/135581905774414259.CrossRefPubMed Maio V, Yuen E, Rabinowitz C, Louis D, Jimbo M, Donatini A, Mall S, Taroni F: Using pharmacy data to identify those with chronic conditions in Emilia Romagna, Italy. J Health Serv Res Policy. 2005, 10 (4): 232-8. 10.1258/135581905774414259.CrossRefPubMed
13.
14.
go back to reference Maio V, Manzoli L: The Italian Health Care System:W.H.O.ranking versus public perception. Pharmacy and Therapeutics. 2002, 27: 301-8. Maio V, Manzoli L: The Italian Health Care System:W.H.O.ranking versus public perception. Pharmacy and Therapeutics. 2002, 27: 301-8.
15.
go back to reference Jommi C, Fattore G: Regionalization and drugs cost-sharing in the Italian NHS. Euro Observer. 2003, 5 (3): 1-4. Jommi C, Fattore G: Regionalization and drugs cost-sharing in the Italian NHS. Euro Observer. 2003, 5 (3): 1-4.
17.
go back to reference D'Ausilio A, Negrini C, Berto P: The pharmaceutical pricing, reimbursement, and prescribing environment in Italy. 2002, Waltham, Mass: Decision Resources Inc D'Ausilio A, Negrini C, Berto P: The pharmaceutical pricing, reimbursement, and prescribing environment in Italy. 2002, Waltham, Mass: Decision Resources Inc
18.
go back to reference Ministry of Health: I Farmaci Del Servizio Sanitario Nazionale Anno I - N.1/2001. Ministry of Health: I Farmaci Del Servizio Sanitario Nazionale Anno I - N.1/2001.
19.
go back to reference WHO: Collaborating Centre for Drug Statistics Methodology (ATC index with DDDs). 2004, Oslo: World health Organization WHO: Collaborating Centre for Drug Statistics Methodology (ATC index with DDDs). 2004, Oslo: World health Organization
20.
go back to reference Clark DO, Von Korff M, Saunders K, Baluch WM, Simon GE: A chronic disease score with empirically derived weights. Medical Care. 1995, 33: 783-95. 10.1097/00005650-199508000-00004.CrossRefPubMed Clark DO, Von Korff M, Saunders K, Baluch WM, Simon GE: A chronic disease score with empirically derived weights. Medical Care. 1995, 33: 783-95. 10.1097/00005650-199508000-00004.CrossRefPubMed
21.
go back to reference Romano PS, Roos LL, Jollis JG: Adapting a clinical comorbidity index for use with ICD-9-CM administrative data: differing perspectives. J Clin Epidemiol. 1993, 46 (10): 1075-9. 10.1016/0895-4356(93)90103-8. discussion 1081-90CrossRefPubMed Romano PS, Roos LL, Jollis JG: Adapting a clinical comorbidity index for use with ICD-9-CM administrative data: differing perspectives. J Clin Epidemiol. 1993, 46 (10): 1075-9. 10.1016/0895-4356(93)90103-8. discussion 1081-90CrossRefPubMed
22.
go back to reference Kreuter F, Valliant R: A survey on survey statistics: What is done and can be done in Stata. The Stata Journal. 2007, 7 (1): 1-21. Kreuter F, Valliant R: A survey on survey statistics: What is done and can be done in Stata. The Stata Journal. 2007, 7 (1): 1-21.
23.
go back to reference Cossman RE, Cossman JS, James WL, Blanchard T, Thomas R, Pol LG, Cosby AG: Correlating pharmaceutical data with a national health survey as a proxy for estimating rural population health. Popul Health Metr. 2010, 14;8: 25-CrossRef Cossman RE, Cossman JS, James WL, Blanchard T, Thomas R, Pol LG, Cosby AG: Correlating pharmaceutical data with a national health survey as a proxy for estimating rural population health. Popul Health Metr. 2010, 14;8: 25-CrossRef
25.
go back to reference Totaro R, Marini C, Pistoia F, Sacco S, Russo T, Carolei A: Prevalence of Parkinson's disease in the L'Aquila district, central Italy. Acta Neurol Scand. 2005, 112 (1): 24-28. 10.1111/j.1600-0404.2005.00426.x.CrossRefPubMed Totaro R, Marini C, Pistoia F, Sacco S, Russo T, Carolei A: Prevalence of Parkinson's disease in the L'Aquila district, central Italy. Acta Neurol Scand. 2005, 112 (1): 24-28. 10.1111/j.1600-0404.2005.00426.x.CrossRefPubMed
27.
go back to reference Martin LM, Leff M, Calonge N, Garrett C, Nelson DE: Validation of self-reported chronic conditions and health services in a managed care population. American Journal of Preventive Medicine. 200;18: 215-8. Martin LM, Leff M, Calonge N, Garrett C, Nelson DE: Validation of self-reported chronic conditions and health services in a managed care population. American Journal of Preventive Medicine. 200;18: 215-8.
28.
go back to reference Boudreau DM, Daling JR, Malone KE, Gardner JS, Blough DK, Heckbert SR: A validation study of patient interview data and pharmacy records for antihypertensive, statin, and antidepressant medication use among older women. American Journal of Epidemiology. 2004, 159: 308-17. 10.1093/aje/kwh038.CrossRefPubMed Boudreau DM, Daling JR, Malone KE, Gardner JS, Blough DK, Heckbert SR: A validation study of patient interview data and pharmacy records for antihypertensive, statin, and antidepressant medication use among older women. American Journal of Epidemiology. 2004, 159: 308-17. 10.1093/aje/kwh038.CrossRefPubMed
29.
go back to reference Mazzaglia G, Yurgin N, Boye KS, Trifirò G, Cottrell S, Allen E, Filippi A, Medea G, Cricelli C: Prevalence and antihyperglycemic prescribing trends for patients with type 2 diabetes in Italy: a 4-year retrospective study from national primary care data. Pharmacol Res. 2008, 57 (5): 358-63. 10.1016/j.phrs.2008.03.009.CrossRefPubMed Mazzaglia G, Yurgin N, Boye KS, Trifirò G, Cottrell S, Allen E, Filippi A, Medea G, Cricelli C: Prevalence and antihyperglycemic prescribing trends for patients with type 2 diabetes in Italy: a 4-year retrospective study from national primary care data. Pharmacol Res. 2008, 57 (5): 358-63. 10.1016/j.phrs.2008.03.009.CrossRefPubMed
30.
go back to reference Saez M, Barceló MA, Coll de Tuero G: A selection-bias free method to estimate the prevalence of hypertension from an administrative primary health care database in the Girona Health Region, Spain. Comput Methods Programs Biomed. 2009, 93 (3): 228-40. 10.1016/j.cmpb.2008.10.010.CrossRefPubMed Saez M, Barceló MA, Coll de Tuero G: A selection-bias free method to estimate the prevalence of hypertension from an administrative primary health care database in the Girona Health Region, Spain. Comput Methods Programs Biomed. 2009, 93 (3): 228-40. 10.1016/j.cmpb.2008.10.010.CrossRefPubMed
31.
go back to reference Chao A, Tsay PK, Lin SH, Shau WY, Chao DY: The applications of capture-recapture models to epidemiological data. Stat Med. 2001, 20 (20): 3123-57. 10.1002/sim.996.CrossRefPubMed Chao A, Tsay PK, Lin SH, Shau WY, Chao DY: The applications of capture-recapture models to epidemiological data. Stat Med. 2001, 20 (20): 3123-57. 10.1002/sim.996.CrossRefPubMed
Metadata
Title
Can we use the pharmacy data to estimate the prevalence of chronic conditions? a comparison of multiple data sources
Authors
Francesco Chini
Patrizio Pezzotti
Letizia Orzella
Piero Borgia
Gabriella Guasticchi
Publication date
01-12-2011
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2011
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-11-688

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