Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
BMC Public Health
Published in: BMC Public Health 1/2010

Open Access 01-12-2010 | Research article

A systematic review of studies measuring health-related quality of life of general injury populations

Authors: Suzanne Polinder, Juanita A Haagsma, Eefje Belt, Ronan A Lyons, Vicki Erasmus, Johan Lund, Ed F van Beeck

Published in: BMC Public Health | Issue 1/2010

Login to get access

Abstract

Background

It is important to obtain greater insight into health-related quality of life (HRQL) of injury patients in order to document people's pathways to recovery and to quantify the impact of injury on population health over time. We performed a systematic review of studies measuring HRQL in general injury populations with a generic health state measure to summarize existing knowledge.

Methods

Injury studies (1995-2009) were identified with main inclusion criteria being the use of a generic health status measure and not being restricted to one specific type of injury. Articles were collated by study design, HRQL instrument used, timing of assessment(s), predictive variables and ability to detect change over time.

Results

Forty one studies met inclusion criteria, using 24 different generic HRQL and functional status measures (most used were SF-36, FIM, GOS, EQ-5D). The majority of the studies used a longitudinal design, but with different lengths and timings of follow-up (mostly 6, 12, and 24 months). Different generic health measures were able to discriminate between the health status of subgroups and picked up changes in health status between discharge and 12 month follow-up. Most studies reported high prevalences of health problems within the first year after injury. The twelve studies that reported HRQL utility scores showed considerable but incomplete recovery in the first year after discharge.

Conclusion

This systematic review demonstrates large variation in use of HRQL instruments, study populations, and assessment time points used in studies measuring HRQL of general injury populations. This variability impedes comparison of HRQL summary scores between studies and prevented formal meta-analyses aiming to quantify and improve precision of the impact of injury on population health over time.
Appendix
Available only for authorised users
Literature
1.
Van Beeck EF, Larsen CF, Lyons RA, Meerding WJ, Mulder S, Essink-Bot ML: Guidelines for the conduction of follow-up studies measuring injury-related disability. J Trauma. 2007, 62 (2): 534-550. 10.1097/TA.0b013e31802e70c7.CrossRefPubMed
2.
Haagsma JA, van Beeck EF, Polinder S, Hoeymans N, Mulder S, Bonsel GJ: Novel empirical disability weights to assess the burden of non-fatal injury. Inj Prev. 2008, 14 (1): 5-10. 10.1136/ip.2007.017178.CrossRefPubMed
3.
World Health Organization: International Classification of Functioning, Disabilities, and Health (ICF). 2001, Geneva: World Health Organization
4.
Segui-Gomez M, Mackenzie EJ: Measuring the Public Health impact of injuries. Epidemiol Rev. 2003, 25: 3-19. 10.1093/epirev/mxg007.CrossRefPubMed
5.
Murray CJ, Lopez AD: Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. The Lancet. 1997, 349 (9063): 1436-1442. 10.1016/S0140-6736(96)07495-8.CrossRef
6.
Derrett S, Black J, Herbison GP: Outcome after injury-a systematic literature search of studies using the EQ-5D. J Trauma. 2009, 67 (4): 883-890. 10.1097/TA.0b013e3181ae6409.CrossRefPubMed
7.
8.
Haagsma JA, Belt E, Polinder S, Lyons RA, Macey S, Atkinson M, Lund J, van Beeck EF: WP5 Injury disability indicators. 2009, Rotterdam: Department of Public Health, Erasmus Medical Center
9.
Lyons RA, Polinder S, Larsen CF, Mulder S, Meerding WJ, Toet H, Van Beeck E: Methodological issues in comparing injury incidence across countries. Int J Inj Contr Saf Promot. 2006, 13 (2): 63-70. 10.1080/17457300500258682.CrossRefPubMed
10.
11.
Aitken ME, Tilford JM, Barrett KW, Parker JG, Simpson P, Landgraf J, Robbins JM: Health status of children after admission for injury. Pediatrics. 2002, 110 (2 Pt 1): 337-342. 10.1542/peds.110.2.337.CrossRefPubMed
12.
Evanoff B, Abedin S, Grayson D, Dale AM, Wolf L, Bohr P: Is disability underreported following work injury?. J Occup Rehabil. 2002, 12 (3): 139-150. 10.1023/A:1016838510682.CrossRefPubMed
13.
Gillen M, Jewell SA, Faucett JA, Yelin E: Functional limitations and well-being in injured municipal workers: a longitudinal study. J Occup Rehabil. 2004, 14 (2): 89-105. 10.1023/B:JOOR.0000018326.23090.63.CrossRefPubMed
14.
Holbrook TL, Anderson JP, Sieber WJ, Browner D, Hoyt B: Outcome after major trauma: discharge and 6-month follow-up results from the Trauma Recovery Project. J Trauma. 1998, 45 (2): 315-323. 10.1097/00005373-199808000-00018.CrossRefPubMed
15.
Holbrook TL, Anderson JP, Sieber WJ, Browner D, Hoyt DB: Outcome after major trauma: 12-month and 18-month follow-up results from the Trauma Recovery Project. J Trauma. 1999, 46 (5): 765-771. 10.1097/00005373-199905000-00003.CrossRefPubMed
16.
Holbrook TL, Hoyt DB: The impact of major trauma: quality-of-life outcomes are worse in women than in men, independent of mechanism and injury severity. J Trauma. 2004, 56 (2): 284-290. 10.1097/01.TA.0000109758.75406.F8.CrossRefPubMed
17.
Keyes KB, Wickizer TM, Franklin G: Two-year health and employment outcomes among injured workers enrolled in the Washington State Managed Care Pilot Project. Am J Ind Med. 2001, 40 (6): 619-626. 10.1002/ajim.10001.CrossRefPubMed
18.
Kiely JM, Brasel KJ, Weidner KL, Guse CE, Weigelt JA: Predicting quality of life six months after traumatic injury. J Trauma. 2006, 61 (4): 791-798. 10.1097/01.ta.0000239360.29852.1d.CrossRefPubMed
19.
Barell V, Aharonson-Daniel L, Fingerhut LA, Mackenzie EJ, Ziv A, Boyko V, Abargel A, Avitzour M, Heruti R: An introduction to the Barell body region by nature of injury diagnosis matrix. Inj Prev. 2002, 8 (2): 91-96. 10.1136/ip.8.2.91.CrossRefPubMedPubMedCentral
20.
Michaels AJ, Michaels CE, Smith JS, Moon CH, Peterson C, Long WB: Outcome from injury: general health, work status, and satisfaction 12 months after trauma. J Trauma. 2000, 48 (5): 841-848; discussion 848-850. 10.1097/00005373-200005000-00007.CrossRefPubMed
21.
Winthrop AL, Brasel KJ, Stahovic L, Paulson J, Schneeberger B, Kuhn EM: Quality of life and functional outcome after pediatric trauma. J Trauma. 2005, 58 (3): 468-473. 10.1097/01.TA.0000153940.23471.B7. discussion 473-464CrossRefPubMed
22.
Aitken ME, Jaffe KM, DiScala C, Rivara FP: Functional outcome in children with multiple trauma without significant head injury. Archives of physical medicine and rehabilitation. 1999, 80 (8): 889-895. 10.1016/S0003-9993(99)90079-5.CrossRefPubMed
23.
Airey CM, Chell SM, Rigby AS, Tennant A, Connelly JB: The epidemiology of disability and occupation handicap resulting from major traumatic injury. Disability and rehabilitation. 2001, 23 (12): 509-515. 10.1080/09638280010010697.CrossRefPubMed
24.
Baldry Currens JA: Evaluation of disability and handicap following injury. Injury. 2000, 31 (2): 99-106. 10.1016/S0020-1383(99)00246-6.CrossRefPubMed
25.
Baldry Currens JA, Coats TJ: The timing of disability measurements following injury. Injury. 2000, 31 (2): 93-98. 10.1016/S0020-1383(99)00244-2.CrossRefPubMed
26.
Braithwaite IJ, Boot DA, Patterson M, Robinson A: Disability after severe injury: five year follow up of a large cohort. Injury. 1998, 29 (1): 55-59. 10.1016/S0020-1383(97)00164-2.CrossRefPubMed
27.
Lyons RA, Towner EE, Kendrick D, Christie N, Brophy S, Phillips CJ, Coupland C, Carter R, Groom L, Sleney J, et al: The UK burden of injury study - a protocol. [National Research Register number: M0044160889]. BMC Public Health. 2007, 7: 317-10.1186/1471-2458-7-317.CrossRefPubMedPubMedCentral
28.
Hetherington H, Earlam RJ, Kirk CJ: The disability status of injured patients measured by the functional independence measure (FIM) and their use of rehabilitation services. Injury. 1995, 26 (2): 97-101. 10.1016/0020-1383(95)92185-D.CrossRefPubMed
29.
Sutherland Aea: Recovery after musculoskeletal trauma in men and women. The Journal of Trauma. 2005, 59 (2): 213-216.CrossRef
30.
Lamers LM, McDonnell J, Stalmeier PF, Krabbe PF, Busschbach JJ: The Dutch tariff: results and arguments for an effective design for national EQ-5 D valuation studies. Health Econ. 2006, 15 (10): 1121-1132. 10.1002/hec.1124.CrossRefPubMed
31.
Gabbe BJ, Cameron PA, Williamson OD, Edwards ER, Graves SE, Richardson MD: The relationship between compensable status and long-term patient outcomes following orthopaedic trauma. Med J Aust. 2007, 187 (1): 14-17.PubMed
32.
Gabbe BJ, Simpson PM, Sutherland AM, Williamson OD, Judson R, Kossmann T, Cameron PA: Functional measures at discharge: are they useful predictors of longer term outcomes for trauma registries?. Ann Surg. 2008, 247 (5): 854-859. 10.1097/SLA.0b013e3181656d1e.CrossRefPubMed
33.
Watson WL, Ozanne-Smith J, Richardson J: Retrospective baseline measurement of self-reported health status and health-related quality of life versus population norms in the evaluation of post-injury losses. Inj Prev. 2007, 13 (1): 45-50. 10.1136/ip.2005.010157.CrossRefPubMedPubMedCentral
34.
Holtslag HR, Post MW, Lindeman E, Van der Werken C: Long-term functional health status of severely injured patients. Injury. 2007, 38 (3): 280-289. 10.1016/j.injury.2006.10.026.CrossRefPubMed
35.
Meerding WJ, Looman CW, Essink-Bot ML, Toet H, Mulder S, van Beeck EF: Distribution and determinants of health and work status in a comprehensive population of injury patients. J Trauma. 2004, 56 (1): 150-161. 10.1097/01.TA.0000062969.65847.8B.CrossRefPubMed
36.
Polinder S, Meerding WJ, van Baar ME, Toet H, Mulder S, van Beeck EF: Cost estimation of injury-related hospital admissions in 10 European countries. J Trauma. 2005, 59 (6): 1283-1290. 10.1097/01.ta.0000195998.11304.5b. discussion 1290-1281CrossRefPubMed
37.
Polinder S, van Beeck EF, Essink-Bot ML, Toet H, Looman CW, Mulder S, Meerding WJ: Functional outcome at 2.5, 5, 9, and 24 months after injury in the Netherlands. J Trauma. 2007, 62 (1): 133-141. 10.1097/TA.0b013e31802b71c9.CrossRefPubMed
38.
Janssens L, Gorter WJ, Ketelaar M, Kramer WLM, Holtslag HR: Long-term health condition in major pediatric trauma: a pilot study. J Pediatric Surgery. 2009, 44: 1591-1600. 10.1016/j.jpedsurg.2009.02.054.CrossRef
39.
Macpherson AK, Rothman L, McKeag AM, Howard A: Mechanism of injury affects 6-month functional outcome in children hospitalized because of severe injuries. J Trauma. 2003, 55 (3): 454-458. 10.1097/01.TA.0000042158.79688.51.CrossRefPubMed
40.
Aitken ME, Tilford JM, Barrett KW, Parker JG, Simpson P, Landgraf J, Robbins JM: Health status of children after admission for injury. Pediatrics. 2002, 110: 337-342. 10.1542/peds.110.2.337.CrossRefPubMed
41.
Gabbe BJ, Cameron PA, Graves SE, Williamson OD, Edwards ER: Preinjury status: are orthopaedic trauma patients different than the general population?. J Orthop Trauma. 2007, 21 (4): 223-228. 10.1097/BOT.0b013e31803eb13c.CrossRefPubMed
42.
Polinder S, van Beeck EF, Essink-Bot ML, Toet H, Looman CW, Mulder S, Meerding WJ: Functional outcome at 2.5, 5, 9, and 24 months after injury in the Netherlands. J Trauma. 2007, 62: 133-141. 10.1097/TA.0b013e31802b71c9.CrossRefPubMed
43.
Soberg HL, Bautz-Holter E, Roise O, Finset A: Long-term multidimensional functional consequences of severe multiple injuries two years after trauma: a prospective longitudinal cohort study. J Trauma. 2007, 62 (2): 461-470. 10.1097/01.ta.0000222916.30253.ea.CrossRefPubMed
44.
Mokkink LB, Terwee CB, Knol DL, Stratford PW, Alonso J, Patrick DL, Bouter LM, de Vet HCW: The COSMIN checklist for evaluating the methodological quality of studies on measurement properties: A clarification of its content. BMC Medical Research Methodology. 2010, 10 (8):
45.
Haagsma JA, Polinder S, Havelaar AH: Analysis and documentation of the results of the reveiw of existing burden of disease methods. 2010, Rotterdam: Department of Public Health, Erasmus Medical Center
46.
Polinder S, Haagsma JA, Bonsel G, Essink-Bot ML, Toet H, van Beeck EF: The measurement of long-term health-related quality of life after injury: comparison of EQ-5 D and the health utilities index. Inj Prev. 16 (3): 147-153. 10.1136/ip.2009.022418.
47.
MacKenzie EJ, Damiano A, Miller T, Luchter S: The development of the Functional Capacity Index. J Trauma. 1996, 41 (5): 799-807. 10.1097/00005373-199611000-00006.CrossRefPubMed
48.
Schluter PJ, Neale R, Scott D, Luchter S, McClure RJ: Validating the functional capacity index: a comparison of predicted versus observed total body scores. J Trauma. 2005, 58 (2): 259-263. 10.1097/01.TA.0000154283.88208.9C.CrossRefPubMed
49.
50.
Garratt A, Schmidt L, Mackintosh A, Fitzpatrick R: Quality of life measurement: bibliographic study of patient assessed health outcome measures. BMJ. 2002, 324: 1417-1421. 10.1136/bmj.324.7351.1417.CrossRefPubMedPubMedCentral
51.
Badia X, Diez-Perez A, Alvarez-Sanz C, Diaz-Lopez B, Diaz-Curiel M, Guillen F, Gonzalez-Macias J, Spanish GSG: Measuring quality of life in women with vertebral fractures due to osteoporosis: a comparison of the OQLQ and QUALEFFO. Qual Life Res. 2001, 10 (4): 307-317. 10.1023/A:1012200508847.CrossRefPubMed
52.
Inaba K, Goecke M, Sharkey P, Brenneman F: Long-term outcomes after injury in the elderly. J Trauma. 2003, 54 (3): 486-491. 10.1097/01.TA.0000051588.05542.D6.CrossRefPubMed
53.
Vles WJ, Steyerberg EW, Essink-Bot ML, van Beeck EF, Meeuwis JD, Leenen LP: Prevalence and determinants of disabilities and return to work after major trauma. J Trauma. 2005, 58 (1): 126-135. 10.1097/01.TA.0000112342.40296.1F.CrossRefPubMed
54.
Zelle B, Stalp M, Weihs C, Müller F, Reiter F, Krettek C, Pape H: Validation of the Hannover Score for Polytrauma Outcome (HASPOC) in a sample of 170 polytrauma patients and a comparison with the 12-Item Short-Form Health Survey [in German]. Chirurg. 2003, 74: 361-369. 10.1007/s00104-003-0621-y.CrossRefPubMed
55.
Janssens L, Gorter JW, Ketelaar M, Kramer WL, Holtslag HR: Health-related quality-of-life measures for long-term follow-up in children after major trauma. Qual Life Res. 2008, 17 (5): 701-713. 10.1007/s11136-008-9339-0.CrossRefPubMedPubMedCentral
56.
Vazquez Mata G, Rivera Fernandez R, Perez Aragon A, Gonzalez Carmona A, Fernandez Mondejar E, Navarrete Navarro P: Analysis of quality of life in polytraumatized patients two years after discharge from an intensive care unit. J Trauma. 1996, 41 (2): 326-332. 10.1097/00005373-199608000-00022.CrossRefPubMed
57.
Gofin R, Adler B: A seven item scale for the assessment of disabilities after child and adolescent injuries. Inj Prev. 1997, 3 (2): 120-123. 10.1136/ip.3.2.120.CrossRefPubMedPubMedCentral
58.
Gofin R, Hass T, Adler B: The development of disability scales for childhood and adolescent injuries. J Clin Epidemiol. 1995, 48 (7): 977-984. 10.1016/0895-4356(94)00198-Y.CrossRefPubMed
59.
Brenneman FD, Redelmeier DA, Boulanger BR, McLellan BA, Culhane JP: Long-term outcomes in blunt trauma: who goes back to work?. J Trauma. 1997, 42 (5): 778-781. 10.1097/00005373-199705000-00004.CrossRefPubMed
60.
61.
Korosec Jagodic H, Jagodic K, Podbregar M: Long-term outcome and quality of life of patients treated in surgical intensive care: a comparison between sepsis and trauma. Crit Care. 2006, 10 (5): R134.-10.1186/cc5047.CrossRefPubMedPubMedCentral
62.
Alves ALA, Salim FM, Martinez EZ, Passos ADC, de Carlo MMRP, Scarpelini S: Quality of life in trauma victims six months after hospital discharge. Rev Saude Publica. 2009, 43: 1-6.CrossRef
63.
Pirente N, Gregor A, Bouillon B, Neugebauer E: Quality of life of severely injured patients 1 year after trauma. A matched-pair study compared with a healthy control group [in German]. Unfallchirurg. 2001, 104: 57-63. 10.1007/s001130050688.CrossRefPubMed
64.
Holtslag HR, van Beeck EF, Lindeman E, Leenen LP: Determinants of long-term functional consequences after major trauma. J Trauma. 2007, 62: 919-927. 10.1097/01.ta.0000224124.47646.62.CrossRefPubMed
65.
Dimopoulou I, Anthi A, Mastora Z, Theodorakopoulou M, Konstandinidis A, Evangelou E, Mandragos K, Roussos C: Health-related quality of life and disability in survivors of multiple trauma one year after intensive care unit discharge. Am J Phys Med Rehabil. 2004, 83 (3): 171-176. 10.1097/01.PHM.0000107497.77487.C1.CrossRefPubMed
66.
Stalp M, Koch C, Regel G, Krettek C, Pape HC: Development of a standardized instrument for quantitative and reproducible rehabilitation data assessment after polytrauma (HASPOC) (in German). Chirurg. 2001, 72: 312-318. 10.1007/s001040051312.CrossRefPubMed
67.
Stalp M, Koch C, Ruchholtz S, Regel G, Panzica M, Krettek C, Pape HC: Standardized outcome evaluation after blunt multiple injuries by scoring systems: a clinical follow-up investigation 2 years after injury. J Trauma. 2002, 52 (6): 1160-1168. 10.1097/00005373-200206000-00023.CrossRefPubMed
Metadata
Title
A systematic review of studies measuring health-related quality of life of general injury populations
Authors
Suzanne Polinder
Juanita A Haagsma
Eefje Belt
Ronan A Lyons
Vicki Erasmus
Johan Lund
Ed F van Beeck
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2010
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-10-783

Other articles of this Issue 1/2010

BMC Public Health 1/2010 Go to the issue

Research article

The evaluation of a Taiwanese training program in smoking cessation and the trainees' adherence to a practice guideline

Research article

Pulmonary impairment after tuberculosis and its contribution to TB burden

Research article

The Edinburgh Addiction Cohort: recruitment and follow-up of a primary care based sample of injection drug users and non drug-injecting controls

Study protocol

Passive smoking in babies: The BIBE study (Brief Intervention in babies. Effectiveness)

Research article

Utilization of delivery care among rural women in china: does the health insurance make a difference? a cross-sectional study

Study protocol

The VicGeneration study - a birth cohort to examine the environmental, behavioural and biological predictors of early childhood caries: background, aims and methods