SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10and PAD in type 2 diabetes

go back to reference Adler AI, Stevens RJ, Neil A, Stratton IM, Boulton AJ, Holman RR: UKPDS 59: hyperglycemia and other potentially modifiable risk factors for peripheral vascular disease in type 2 diabetes. Diabetes Care. 2002, 25: 894-899. 10.2337/diacare.25.5.894.CrossRefPubMed Adler AI, Stevens RJ, Neil A, Stratton IM, Boulton AJ, Holman RR: UKPDS 59: hyperglycemia and other potentially modifiable risk factors for peripheral vascular disease in type 2 diabetes. Diabetes Care. 2002, 25: 894-899. 10.2337/diacare.25.5.894.CrossRefPubMed

go back to reference Keen H, Clark C, Laakso M: Reducing the burden of diabetes: managing cardiovascular disease. Diabetes Metab Res Rev. 1999, 15: 186-196. 10.1002/(SICI)1520-7560(199905/06)15:3<186::AID-DMRR30>3.0.CO;2-5.CrossRefPubMed Keen H, Clark C, Laakso M: Reducing the burden of diabetes: managing cardiovascular disease. Diabetes Metab Res Rev. 1999, 15: 186-196. 10.1002/(SICI)1520-7560(199905/06)15:3<186::AID-DMRR30>3.0.CO;2-5.CrossRefPubMed

go back to reference Carmelli D, Fabsitz RR, Swan GE, Reed T, Miller B, Wolf PA: Contribution of genetic and environmental influences to ankle-brachial blood pressure index in the NHLBI Twin Study. National Heart, Lung, and Blood Institute. Am J Epidemiol. 2000, 151: 452-458.CrossRefPubMed Carmelli D, Fabsitz RR, Swan GE, Reed T, Miller B, Wolf PA: Contribution of genetic and environmental influences to ankle-brachial blood pressure index in the NHLBI Twin Study. National Heart, Lung, and Blood Institute. Am J Epidemiol. 2000, 151: 452-458.CrossRefPubMed

go back to reference Gudmundsson G, Matthiasson SE, Arason H, Johannsson H, Runarsson F, Bjarnason H, et al: Localization of a Gene for Peripheral Arterial Occlusive Disease to Chromosome 1p31. Am J Hum Genet. 2002, 70: 586-592. 10.1086/339251.CrossRefPubMedPubMedCentral Gudmundsson G, Matthiasson SE, Arason H, Johannsson H, Runarsson F, Bjarnason H, et al: Localization of a Gene for Peripheral Arterial Occlusive Disease to Chromosome 1p31. Am J Hum Genet. 2002, 70: 586-592. 10.1086/339251.CrossRefPubMedPubMedCentral

go back to reference Coucke PJ, Willaert A, Wessels MW, Callewaert B, Zoppi N, De Backer J, et al: Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome. Nat Genet. 2006, 38: 452-457. 10.1038/ng1764.CrossRefPubMed Coucke PJ, Willaert A, Wessels MW, Callewaert B, Zoppi N, De Backer J, et al: Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome. Nat Genet. 2006, 38: 452-457. 10.1038/ng1764.CrossRefPubMed

go back to reference Drera B, Guala A, Zoppi N, Gardella R, Franceschini P, Barlati S, et al: Two novel SLC2A10/GLUT10 mutations in a patient with arterial tortuosity syndrome. Am J Med Genet A. 2007, 143: 216-218.CrossRef Drera B, Guala A, Zoppi N, Gardella R, Franceschini P, Barlati S, et al: Two novel SLC2A10/GLUT10 mutations in a patient with arterial tortuosity syndrome. Am J Med Genet A. 2007, 143: 216-218.CrossRef

go back to reference Zaidi SH, Meyer S, Peltekova VD, Lindinger A, Teebi AS, Faiyaz-Ul-Haque M: A novel non-sense mutation in the SLC2A10 gene of an arterial tortuosity syndrome patient of Kurdish origin. Eur J Pediatr. 2008. Zaidi SH, Meyer S, Peltekova VD, Lindinger A, Teebi AS, Faiyaz-Ul-Haque M: A novel non-sense mutation in the SLC2A10 gene of an arterial tortuosity syndrome patient of Kurdish origin. Eur J Pediatr. 2008.

go back to reference Callewaert BL, Willaert A, Kerstjens-Frederikse WS, De Backer J, Devriendt K, Albrecht B, et al: Arterial tortuosity syndrome: clinical and molecular findings in 12 newly identified families. Hum Mutat. 2008, 29: 150-158. 10.1002/humu.20623.CrossRefPubMed Callewaert BL, Willaert A, Kerstjens-Frederikse WS, De Backer J, Devriendt K, Albrecht B, et al: Arterial tortuosity syndrome: clinical and molecular findings in 12 newly identified families. Hum Mutat. 2008, 29: 150-158. 10.1002/humu.20623.CrossRefPubMed

go back to reference Brownlee M: The Pathobiology of Diabetic Complications. A Unifying Mechanism. Diabetes. 2005, 54: 1615-1625. 10.2337/diabetes.54.6.1615.CrossRefPubMed Brownlee M: The Pathobiology of Diabetic Complications. A Unifying Mechanism. Diabetes. 2005, 54: 1615-1625. 10.2337/diabetes.54.6.1615.CrossRefPubMed

go back to reference Ziyadeh FN: Mediators of Diabetic Renal Disease: The case for TGF-β as the major mediator. J Am Soc Nephrol. 2004, 15: S55-S57. 10.1097/01.ASN.0000093460.24823.5B.CrossRefPubMed Ziyadeh FN: Mediators of Diabetic Renal Disease: The case for TGF-β as the major mediator. J Am Soc Nephrol. 2004, 15: S55-S57. 10.1097/01.ASN.0000093460.24823.5B.CrossRefPubMed

go back to reference Chiarelli F, Santilli F, Mohn A: Role of growth factors in the development of diabetic complications. Hormone Research. 2000, 53: 53-67. 10.1159/000023515.CrossRefPubMed Chiarelli F, Santilli F, Mohn A: Role of growth factors in the development of diabetic complications. Hormone Research. 2000, 53: 53-67. 10.1159/000023515.CrossRefPubMed

go back to reference Alberti KG, Zimmet PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1:diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998, 15: 539-553. 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S.CrossRefPubMed Alberti KG, Zimmet PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1:diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998, 15: 539-553. 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S.CrossRefPubMed

go back to reference Hirsch AT, Haskal ZJ, Hertzer NR, Bakal CW, Creager MA, Halperin JL, et al: ACC/AHA 2005 Guidelines for the Management of Patients With Peripheral Arterial Disease (Lower Extremity, Renal, Mesenteric, and Abdominal Aortic): Executive Summary A Collaborative Report From the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease) Endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. J Am Coll Cardiol. 2006, 47: 1239-1312. 10.1016/j.jacc.2005.10.009.CrossRefPubMed Hirsch AT, Haskal ZJ, Hertzer NR, Bakal CW, Creager MA, Halperin JL, et al: ACC/AHA 2005 Guidelines for the Management of Patients With Peripheral Arterial Disease (Lower Extremity, Renal, Mesenteric, and Abdominal Aortic): Executive Summary A Collaborative Report From the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease) Endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. J Am Coll Cardiol. 2006, 47: 1239-1312. 10.1016/j.jacc.2005.10.009.CrossRefPubMed

go back to reference Lin WH, Chuang LM, Chen CH, Yeh JI, Hsieh PS, Cheng CH, et al: An association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in Taiwanese population. Diabetologia. 2006, 49: 1214-1221. 10.1007/s00125-006-0218-3.CrossRefPubMed Lin WH, Chuang LM, Chen CH, Yeh JI, Hsieh PS, Cheng CH, et al: An association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in Taiwanese population. Diabetologia. 2006, 49: 1214-1221. 10.1007/s00125-006-0218-3.CrossRefPubMed

go back to reference Barrett JC, Fry B, Maller J, Daly MJ: Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005, 21: 263-265. 10.1093/bioinformatics/bth457.CrossRefPubMed Barrett JC, Fry B, Maller J, Daly MJ: Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005, 21: 263-265. 10.1093/bioinformatics/bth457.CrossRefPubMed

go back to reference Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA: Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet. 2002, 70: 425-434. 10.1086/338688.CrossRefPubMed Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA: Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet. 2002, 70: 425-434. 10.1086/338688.CrossRefPubMed

go back to reference Mueckler M: Family of glucose-transporter genes. Implications for glucose homeostasis and diabetes. Diabetes. 1990, 39: 6-11. 10.2337/diabetes.39.1.6.CrossRefPubMed Mueckler M: Family of glucose-transporter genes. Implications for glucose homeostasis and diabetes. Diabetes. 1990, 39: 6-11. 10.2337/diabetes.39.1.6.CrossRefPubMed

go back to reference Cheng CH, Kikuchi T, Chen YH, Sabbagha NG, Lee YC, Pan HJ, et al: Mutations in the SLC2A10 gene cause arterial abnormalities in mice. Cardiovasc Res. 2008. Cheng CH, Kikuchi T, Chen YH, Sabbagha NG, Lee YC, Pan HJ, et al: Mutations in the SLC2A10 gene cause arterial abnormalities in mice. Cardiovasc Res. 2008.

go back to reference Andersen G, Rose CS, Hamid YH, Drivsholm T, Borch-Johnsen K, Pedersen O: Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationship to type 2 diabetes and intermediary traits. Diabetes. 2003, 52: 2445-2448. 10.2337/diabetes.52.9.2445.CrossRefPubMed Andersen G, Rose CS, Hamid YH, Drivsholm T, Borch-Johnsen K, Pedersen O: Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationship to type 2 diabetes and intermediary traits. Diabetes. 2003, 52: 2445-2448. 10.2337/diabetes.52.9.2445.CrossRefPubMed

go back to reference Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, et al: Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature. 2005, 434: 338-345. 10.1038/nature03441.CrossRefPubMedPubMedCentral Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, et al: Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature. 2005, 434: 338-345. 10.1038/nature03441.CrossRefPubMedPubMedCentral

go back to reference Chaturvedi N, Stevens LK, Fuller JH, Lee ET, Lu M: Risk factors, ethnic differences and mortality associated with lower-extremity gangrene and amputation in diabetes. The WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia. 2001, 44 (Suppl 2): S65-71. 10.1007/PL00002941.CrossRefPubMed Chaturvedi N, Stevens LK, Fuller JH, Lee ET, Lu M: Risk factors, ethnic differences and mortality associated with lower-extremity gangrene and amputation in diabetes. The WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia. 2001, 44 (Suppl 2): S65-71. 10.1007/PL00002941.CrossRefPubMed

go back to reference Beks PJ, Mackaay AJ, de Neeling JN, de Vries H, Bouter LM, Heine RJ: Peripheral arterial disease in relation to glycemic level in an elderly Caucasian population: the Hoorn study. Diabetologia. 1995, 38: 86-96. 10.1007/BF02369357.CrossRefPubMed Beks PJ, Mackaay AJ, de Neeling JN, de Vries H, Bouter LM, Heine RJ: Peripheral arterial disease in relation to glycemic level in an elderly Caucasian population: the Hoorn study. Diabetologia. 1995, 38: 86-96. 10.1007/BF02369357.CrossRefPubMed

go back to reference Premalatha G, Shanthirani S, Deepa R, Markovitz J, Mohan V: Prevalence and risk factors of peripheral vascular disease in a selected south India population. Diabetes Care. 2000, 23: 1295-1300. 10.2337/diacare.23.9.1295.CrossRefPubMed Premalatha G, Shanthirani S, Deepa R, Markovitz J, Mohan V: Prevalence and risk factors of peripheral vascular disease in a selected south India population. Diabetes Care. 2000, 23: 1295-1300. 10.2337/diacare.23.9.1295.CrossRefPubMed

go back to reference The International HapMap Consortium: The International HapMap Project. Nature. 2003, 426: 789-796. 10.1038/nature02168.CrossRef The International HapMap Consortium: The International HapMap Project. Nature. 2003, 426: 789-796. 10.1038/nature02168.CrossRef

go back to reference Yang HC, Lin CH, Hsu CL, Hung SI, Wu JY, Pen WH, Chen YT, Fann CS: A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians. J Biomed Sci. 2006, 13: 489-98. 10.1007/s11373-006-9077-7.CrossRefPubMed Yang HC, Lin CH, Hsu CL, Hung SI, Wu JY, Pen WH, Chen YT, Fann CS: A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians. J Biomed Sci. 2006, 13: 489-98. 10.1007/s11373-006-9077-7.CrossRefPubMed