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Open Access 01-12-2006 | Review

Wnt signalling in lung development and diseases

Authors: Judit E Pongracz, Robert A Stockley

Published in: Respiratory Research | Issue 1/2006

Abstract

There are several signalling pathways involved in lung organogenesis including Notch, TGFβ /BMP, Sonic hedgehog (Shh), FGF, EGF, and Wnt. Despite the widely acknowledged significance of Wnt signalling in embryonic lung development, the role of different Wnt pathways in lung pathologies has been slow to emerge.

In this review, we will present a synopsis of current Wnt research with particular attention paid to the role of Wnt signals in lung development and in pulmonary diseases.

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Title: Wnt signalling in lung development and diseases
Authors: Judit E Pongracz
Robert A Stockley
Publication date: 01-12-2006
Publisher: BioMed Central
Published in: Respiratory Research / Issue 1/2006
Electronic ISSN: 1465-993X
DOI: https://doi.org/10.1186/1465-9921-7-15

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