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The Journal of Headache and Pain
Published in: The Journal of Headache and Pain 1/2014

Open Access 01-12-2014 | Meeting abstract

EHMTI-0125. Studying the permeability of the blood-brain barrier during migraine attacks using [11C]-dihydroergotamine

Authors: C Schankin, F Maniyar, Y Seo, S Kori, M Eller, J Blecha, S Murphy, T Sprenger, H VanBrocklin, P Goadsby

Published in: The Journal of Headache and Pain | Special Issue 1/2014

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Excerpt

Due to unfavorable molecular size and lipophilicity, migraine-specific medications such as dihydroergotamine (DHE) are not expected to penetrate the blood-brain barrier (BBB). A breakdown of the BBB during migraine attacks has been postulated as the mechanism in which DHE accesses postulated central sites of action. …
Metadata
Title
EHMTI-0125. Studying the permeability of the blood-brain barrier during migraine attacks using [11C]-dihydroergotamine
Authors
C Schankin
F Maniyar
Y Seo
S Kori
M Eller
J Blecha
S Murphy
T Sprenger
H VanBrocklin
P Goadsby
Publication date
01-12-2014
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue Special Issue 1/2014
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/1129-2377-15-S1-F22

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