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Cancer Imaging
Published in: Cancer Imaging 2/2001

Open Access 01-12-2001 | Review

Detection of peritoneal metastases

Author: Dr Jeremiah C. Healy

Published in: Cancer Imaging | Issue 2/2001

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Abstract

The peritoneum is the largest and most complexly arranged serous membrane in the body. The potential peritoneal spaces, the peritoneal reflections forming peritoneal ligaments, mesenteries, omenta, and the natural flow of peritoneal fluid determine the route of spread of intraperitoneal fluid and consequently disease spread within the abdominal cavity. The peritoneal ligaments, mesenteries, and omenta also serve as boundaries and conduits for disease spread. Peritoneal metastases spread in four ways:
  • Direct spread along peritoneal ligaments, mesenteries and omenta to non-contiguous organs
  • Intraperitoneal seeding via ascitic fluid
  • Lymphatic extension
  • Embolic haematogenous spread.
Before the introduction of cross-sectional imaging, the peritoneum and its reflections could only be imaged with difficulty, often requiring invasive techniques. Computed tomography and to a lesser extent sonography and MR imaging allow us to examine the complex anatomy of the peritoneal cavity accurately, which is the key to understanding the spread of peritoneal metastases. This article reviews the detection of peritoneal metastases.
Literature
1.
Oliphant M, Berne AS, Meyers MA. The subperitoneal space of the abdomen and pelvis: Planes of continuity. AJR 1996; 167: 1433–39.PubMed
2.
Halvorsen RA, Panushka C, Oakley GJ et al. Intraperitoneal contrast material improves the CT detection of peritoneal metastases. AJR 1991; 157: 37–40.PubMed
3.
Nelson RC, Chezmar JL, Hoel MJ, Buck DR, Sugarbaker PH. Peritoneal carcinomatosis: Preoperative CT with intraperitoneal contrast material. Radiology 1992; 182: 133–8.PubMed
4.
Caseiro-Alves F, Goncalo M, Abraul E et al. Induced pneumoperitoneum in CT evaluation of peritoneal carcinomatosis. Abdom Imaging 1995; 20: 52–55.PubMed
5.
Choi CK, Liu GC, Chen LT et al. MRI manifestations of peritoneal carcinomatosis. Gastrointest Radiol 1992; 17: 336–8.
6.
Chou C-K, Liu G-C, Su J-H et al. MRI demonstration of peritoneal implants. Abdominal Imaging 1994; 19: 95.PubMed
7.
Semelka RC, Lawrence PH, Shoenut JP, Heywood M, Kroeker MA, Lotocki R. Primary ovarian cancer: Prospective comparison of contrast enhanced CT and pre- and post-contrast, fat suppressed MR imaging, with histologic correlation. J Mag Res Imaging 1993; 3: 99–106.
8.
Tempany CM, Zou KH, Silverman SG et al. Staging of advanced ovarian cancer: Comparison of imaging modalities — Report from the Radiology Diagnostic Oncology Group. Radiology 2000; 215: 761–7.PubMed
9.
Derchi LE, Solbiati L, Rizziatto G et al. Normal anatomy and pathological changes of the small bowel mesentery: US appearance. Radiology 1987; 164: 649–52.PubMed
10.
Goerg C, Schwerk W-B. Malignant ascites: Sonographic signs of peritoneal carcinomatosis. Eur J Cancer 1991; 27: 720–3.PubMed
11.
Carrasquillo JA, Sugarbaker P, Colcher D et al. Peritoneal carcinomatosis: Imaging with intraperitoneal injection of I-131-labelled B72.3 monoclonal antibody. Radiology 1988; 167: 35–40.PubMed
12.
Meyers MA, Oliphant M, Berne MS et al. The peritoneal ligaments and mesenteries: Pathways of intra-abdominal spread of disease. Annual oration. Radiology 1987; 163: 595–604.
13.
Oliphant M, Berne A, Meyers MA. Subperitoneal spread of intra-abdominal disease. In Computed tomography of the gastrointestinal tract including the peritoneal cavity and mesentery. Edited by MA Myers. Springer Verlag, New York, 1986, pp. 95–137.
14.
Balfe DM, Mauro MA, Kooehler RE et al. Gastrohepatic ligament: Normal and pathologic CT anatomy. Radiology 1984; 150: 485–90.PubMed
15.
Dehn CB, Reznek RH, Nockler B et al. The preoperative assessment of advanced gastric cancer by computed tomography. Br J Surg 1984; 71: 413–7.PubMed
16.
Weinstein JB, Heiken JP, Lee JKT et al. High resolution CT of the porta hepatis and hepatoduodenal ligament. Radiographics 1986; 6(1): 55–73.PubMed
17.
Baker ME, Silverman PM, Halvorsen RA et al. Computed tomography of masses in periportal/hepatoduodenal ligament. J Comput Assist Tomogr 1987; 11: 258–63.PubMed
18.
Kim TK, Han JK, Chung JW, Choi BI, Park JH, Han MC. Intraperitoneal drop metastases from hepatocellular carcinoma: CT and angiographic findings. J. Comput Assist Tomogr 1996; 20(4): 638–42.PubMed
19.
Ohtani T, Shirai Y, Tsukada K, Muto T, Hatakeyama K. Spread of gallbladder carcinoma: CT evaluation with pathologic correlation. Abdom Imaging 1996; 21(3): 195–201.PubMed
20.
Diamond RT, Greenberg HM, Boult IF. Direct metastatic spread of right colonic denocarcinoma to duodenum: Barium and computed tomography findings. Gastrointest Radiol 1981; 6: 339–41.PubMed
21.
McDaniel KP, Charnsangavej C, Du Brow et al. Pathways of nodal metastases in carcinomas of the cecum, ascending colon, and transverse colon. CT demonstration. AJR 1993; 160: 49–52.
22.
Chun CH, Raff MF, Conteras L et al. Splenic abscess. Medicine (Baltimore) 1980; 59: 50–65.
23.
Meyers MA. Distribution of intraabdominal malignant seeding: Dependency on dynamics of flow of ascitic fluid. AJR 1973; 119: 198–206.
24.
Bergman F. Carcinoma of the ovary: A clinicopathological study of 86 autopsied cases with special reference to mode of spread. Acta Obstet Gynaecol 1966; 45: 211–31.
25.
Dagnini G, Marin G, Caldironin MW et al. Laparoscopy in staging, follow-up, and re-staging ovarian carcinoma. Gastrointest Endoscop 1987; 33: 80–83.
26.
Jeffrey RB Jr. CT demonstration of peritoneal implants. AJR 1980; 135: 323–6.PubMed
27.
Buy J-N, Moss AA, Ghossain MA et al. Peritoneal implants from ovarian tumours: CT findings. Radiology 1988; 169: 691–4.PubMed
28.
Megibow AJ, Bosniak MA, Ho AG et al. Accuracy CT in detection of persistent or recurrent ovarian carcinoma: Correlation with second look laparotomy. Radiology 1988; 166: 341–54.PubMed
29.
Triller J, Goldnirsch A, Reinhard J-P. Subscapular liver metastases in ovarian cancer: Computer tomography and surgical staging. Eur J Radiol 1985; 5: 261–6.PubMed
30.
Walkey MM, Friedman AC, Sohotra P et al. CT manifestations of peritoneal carcinomatosis. AJR 1988; 150: 1035–41.PubMed
31.
Mitchell DG, Hill MC, Hill S et al. Serous carcinoma of the ovary: CT identification of metastatic calcified implants. Radiology 1986; 158: 649–52.PubMed
32.
Matsuoka K, Okuhira M, Nonaka T et al. Calcification of peritoneal carcinomatosis from gastric carcinoma: a CT demonstration. Eur J Radiol 1991; 13: 207–8.PubMed
33.
Woodard PK, Feldman JM, Paine SS, Baker ME. Midgut carcinoid tumours: CT findings and biochemical profiles. J Comput Assist Tomogr 1995; 19: 400–5.PubMed
34.
Seshul MB, Coulam CM. Pseudomyxoma peritonei: Computed tomography and sonography. AJR 1981; 136: 803–6.PubMed
35.
Whitley NO, Bohlman ME, Baker LP. CT patterns of mesenteric disease. J Comput Assist Tomogr 1982; 6: 490–6.PubMed
36.
Cooper C, Jeffrey RB, Silverman PM et al. Computed tomography of omental pathology. J Comput Assist Tomogr 1986; 10: 62–6.PubMed
37.
Pandolfo I, Blandino A, Gaeta M et al. Calcified peritoneal metastases from papillary cystadenocarcinoma of the ovary: CT features. J Comput Assist Tomogr 1986; 10: 545–6.PubMed
38.
Tartar VM, Heiken JP, McClellan BL. Renal cell carcinoma presenting with diffuse peritoneal metastases: CT findings. J Comput Assist Tomogr 1991; 15(3): 450–3.PubMed
39.
Cho KC, Gold BM. Computed Tomography of Krukenberg tumours. AJR 1985; 145: 285–86.PubMed
40.
Goffinet DR, Castellino RA, Kim H et al. Staging laparotomies in unselected patients with non-Hodgkin’s lymphoma. Cancer 1973; 32: 672–81.PubMed
41.
Mueller PR, Ferrucci JT Jr, Harbin WP et al. Appearance of lymphomatous involvement of the mesentery by ultrasonography and body computer tomography: the ‘sandwich sign’. Radiology 1980; 134: 467–73.PubMed
42.
Kawashima A, Fishman EK, Kuhlman JE et al. CT of malignant melanoma: Patterns of small bowel and mesenteric involvement. J Comput Assist Tomogr 1991; 15(4): 570–4.PubMed
43.
Caskey CI, Scatarige JC, Fishman EK. Distribution of metastases in breast carcinoma. CT evaluation of the abdomen. Clin Imaging 1991; 15: 166–71.PubMed
44.
Oddson TA, Rice RRP, Seiler HF et al. The spectrum of small bowel melanoma. Gastrointest Radiol 1978; 3: 419–23.PubMed
45.
Pectasides D, Kayianni H, Facou A et al. Correlation of abdominal computed tomography scanning and second look operation findings in ovarian cancer patients. Am J Clin Oncol 1991; 14: 457–62.PubMed
46.
De-Rosa V, Mangoni-di-Stefano ML, Brunetti A et al. Computed tomography and second-look surgery in ovarian cancer patients. Correlation, actual role and limitations of CT scan. Eur J Gynaecol Oncol 1995; 16: 123–9.PubMed
47.
Brady PG, Peebles M, Goldschmid S. Role of laparoscopy in the evaluation of patients with suspected hepatic or peritoneal malignancy. Gastrointest Endosc 1991; 37: 27–30.PubMed
Metadata
Title
Detection of peritoneal metastases
Author
Dr Jeremiah C. Healy
Publication date
01-12-2001
Publisher
BioMed Central
Published in
Cancer Imaging / Issue 2/2001
Electronic ISSN: 1470-7330
DOI
https://doi.org/10.1102/1470-7330.2001.002
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