Published in:
01-12-2015 | Sleep Epidemiology (J Nieto, Section Editor)
The Association Between Sleep Duration and Leptin, Ghrelin, and Adiponectin Among Children and Adolescents
Authors:
Erika W. Hagen, Samuel J. Starke, Paul E. Peppard
Published in:
Current Sleep Medicine Reports
|
Issue 4/2015
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Abstract
Several studies suggest that habitually shorter-sleep duration is associated with higher risk for overweight and obesity among children. Multiple plausible mechanisms may link chronic short sleep to weight gain among humans, including pathologic alterations in energy-regulating and appetite-influencing hormones. In this manuscript, we review the literature that examines associations between three such hormones—leptin, ghrelin, and adiponectin—and sleep duration, in studies of children and adolescents. The results of this review suggest that there is not currently sufficient evidence to definitively implicate each of these hormones in the sleep duration-obesity pathway in children. However, there are several studies with significant findings, such that a role for sleep curtailment-induced hormonal changes is plausible. Further work is required to elucidate the specific role these hormones play in metabolic dysregulation associated with chronic short sleep.