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Published in: Current Oral Health Reports 2/2024

Open Access 16-02-2024 | Caries

A Review on Enhancing the Life of Teeth by Toothpaste Containing Bioactive Glass Particles

Authors: P. Syam Prasad, Mahammod Babar Pasha, R. Narasimha Rao, P. Venkateswara Rao, Narayanan Madaboosi, Mutlu Özcan

Published in: Current Oral Health Reports | Issue 2/2024

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Abstract

Purpose of Review

Dental caries or tooth decay is one of the communal problems in the world which can affect not only the oral health but also the general health conditions. The main objective of this systematic review is to explore the efficacy of bioactive glass-based toothpastes against cariogenic bacteria.

Recent Findings

Bioactive glass particulates containing toothpaste show better remineralization potential on demineralized enamel and dentin when compared with toothpaste containing various bioactive constituents such as fluoride and potassium chloride. These constituents in conventional toothpaste can rapidly streak off due to acidic impact in the oral environment as the bioactive glass provides minerals for demineralized enamel and dentin by forming a strong hydroxyapatite (HAp) layer on its surface. Further, the therapeutic ions present in the bioglass can resist plaque formation by raising the pH of the surrounding environment or saliva and create amicable media for healthier teeth.

Summary

Toothpaste containing bioactive glass particles undoubtedly displayed the remineralizing potentiality of the dental hard tissues. Dynamics of the mineralization through different bioactive glass materials needs further investigations. In order to prevent dental cavities and improve oral health, it is important to identify and study different effective bioglass particles in toothpaste.
Literature
2.
go back to reference Baik A, Alamoudi N, El-Housseiny A, Altuwirqi A. Fluoride varnishes for preventing occlusal dental caries: areview. Dent J. 2021;9(6):1–15.CrossRef Baik A, Alamoudi N, El-Housseiny A, Altuwirqi A. Fluoride varnishes for preventing occlusal dental caries: areview. Dent J. 2021;9(6):1–15.CrossRef
4.
go back to reference Caufield PW, Schön CN, Saraithong P, Li Y, Argimón S. Oral lactobacilli and dental caries: a model for niche adaptation in humans. J Dent Res. 2015;94(X):110S-118S.CrossRefPubMedPubMedCentral Caufield PW, Schön CN, Saraithong P, Li Y, Argimón S. Oral lactobacilli and dental caries: a model for niche adaptation in humans. J Dent Res. 2015;94(X):110S-118S.CrossRefPubMedPubMedCentral
5.
go back to reference Kammoun R, Zmantar T, Labidi A, Abbes I, Mansour L, Ghoul-Mazgar S. Dental caries and hypoplastic amelogenesis imperfecta: clinical, structural, biochemical and molecular approaches. Microb Pathog [Internet]. 2019;135(June):103615.CrossRefPubMed Kammoun R, Zmantar T, Labidi A, Abbes I, Mansour L, Ghoul-Mazgar S. Dental caries and hypoplastic amelogenesis imperfecta: clinical, structural, biochemical and molecular approaches. Microb Pathog [Internet]. 2019;135(June):103615.CrossRefPubMed
6.
go back to reference Jain I, Jain P, Bisht D, Sharma A, Srivastava B, Gupta N. Use of traditional Indian plants in the inhibition of caries-causing bacteria - Streptococcus mutans. Braz Dent J. 2015;26(2):110–5.CrossRefPubMed Jain I, Jain P, Bisht D, Sharma A, Srivastava B, Gupta N. Use of traditional Indian plants in the inhibition of caries-causing bacteria - Streptococcus mutans. Braz Dent J. 2015;26(2):110–5.CrossRefPubMed
8.
go back to reference Marto CM, Baptista Paula A, Nunes T, Pimenta M, Abrantes AM, Pires AS, et al. Evaluation of the efficacy of dentin hypersensitivity treatments—a systematic review and follow-up analysis. J Oral Rehabil. 2019;46(10):952–90.CrossRefPubMed Marto CM, Baptista Paula A, Nunes T, Pimenta M, Abrantes AM, Pires AS, et al. Evaluation of the efficacy of dentin hypersensitivity treatments—a systematic review and follow-up analysis. J Oral Rehabil. 2019;46(10):952–90.CrossRefPubMed
9.
go back to reference Aminoshariae A, Kulild JC. Current concepts of dentinal hypersensitivity. J Endod [Internet]. 2021;47(11):1696–702.CrossRefPubMed Aminoshariae A, Kulild JC. Current concepts of dentinal hypersensitivity. J Endod [Internet]. 2021;47(11):1696–702.CrossRefPubMed
10.
go back to reference Favaro Zeola L, Soares PV, Cunha-Cruz J. Prevalence of dentin hypersensitivity: systematic review and meta-analysis. J Dent [Internet]. 2018;2019(81):1–6. Favaro Zeola L, Soares PV, Cunha-Cruz J. Prevalence of dentin hypersensitivity: systematic review and meta-analysis. J Dent [Internet]. 2018;2019(81):1–6.
11.
go back to reference •• Arshad S, Zaidi SJA, Farooqui WA. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial. BMC Oral Health [Internet]. 2021;21(1):1–12. A clinical investigation providing insights into the most effective treatment approach for both short-term and long-term management of DH using over-the-counter dentifrices. •• Arshad S, Zaidi SJA, Farooqui WA. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial. BMC Oral Health [Internet]. 2021;21(1):1–12. A clinical investigation providing insights into the most effective treatment approach for both short-term and long-term management of DH using over-the-counter dentifrices.
13.
go back to reference Rezazadeh F, Dehghanian P, Jafarpour D. Laser effects on the prevention and treatment of dentinal hypersensitivity: a systematic review. J Lasers Med Sci [Internet]. 2019;10(1):1–11.PubMed Rezazadeh F, Dehghanian P, Jafarpour D. Laser effects on the prevention and treatment of dentinal hypersensitivity: a systematic review. J Lasers Med Sci [Internet]. 2019;10(1):1–11.PubMed
16.
go back to reference •• Behzadi S, Mohammadi Y, Rezaei-Soufi L, Farmany A. Occlusion effects of bioactive glass and hydroxyapatite on dentinal tubules: a systematic review. Clin Oral Investig [Internet]. 2022;26(10):6061–78. A thorough systematic review evaluating the capacity of bioactive glass and hydroxyapatite to seal exposed dentin tubules.CrossRefPubMed •• Behzadi S, Mohammadi Y, Rezaei-Soufi L, Farmany A. Occlusion effects of bioactive glass and hydroxyapatite on dentinal tubules: a systematic review. Clin Oral Investig [Internet]. 2022;26(10):6061–78. A thorough systematic review evaluating the capacity of bioactive glass and hydroxyapatite to seal exposed dentin tubules.CrossRefPubMed
17.
go back to reference Kiesow A, Menzel M, Lippert F, Tanzer JM, Milgrom P. Dentin tubule occlusion by a 38% silver diamine fluoride gel: an in vitro investigation. BDJ Open. 2022;8(1):1–5.CrossRefPubMedPubMedCentral Kiesow A, Menzel M, Lippert F, Tanzer JM, Milgrom P. Dentin tubule occlusion by a 38% silver diamine fluoride gel: an in vitro investigation. BDJ Open. 2022;8(1):1–5.CrossRefPubMedPubMedCentral
18.
go back to reference Skallevold HE, Rokaya D, Khurshid Z, Zafar MS. Bioactive glass applications in dentistry. Int J Mol Sci. 2019;20(23):1–24.CrossRef Skallevold HE, Rokaya D, Khurshid Z, Zafar MS. Bioactive glass applications in dentistry. Int J Mol Sci. 2019;20(23):1–24.CrossRef
19.
go back to reference Abbasi Z, Bahroloolum ME, Shariat MH, Bagheri R. Bioactive glasses in dentistry : a review. J Glas Dent A Rev. 2015;2(1):1–9. Abbasi Z, Bahroloolum ME, Shariat MH, Bagheri R. Bioactive glasses in dentistry : a review. J Glas Dent A Rev. 2015;2(1):1–9.
21.
go back to reference • Simila HO, Boccaccini AR. Sol-gel bioactive glass containing biomaterials for restorative dentistry: a review. Dent Mater [Internet]. 2022;38(5):725–47. This review illustrates that sol-gel synthesis offers limitless possibilities for conceptualizing, synthesizing, and processing innovative bioactive dental biomaterial formulations.CrossRefPubMed • Simila HO, Boccaccini AR. Sol-gel bioactive glass containing biomaterials for restorative dentistry: a review. Dent Mater [Internet]. 2022;38(5):725–47. This review illustrates that sol-gel synthesis offers limitless possibilities for conceptualizing, synthesizing, and processing innovative bioactive dental biomaterial formulations.CrossRefPubMed
22.
go back to reference Singh S, Patil A, Mali S, Jaiswal H. Bioglass: a new era in modern dentistry. Eur J Gen Dent. 2022;11(1):001–6.CrossRef Singh S, Patil A, Mali S, Jaiswal H. Bioglass: a new era in modern dentistry. Eur J Gen Dent. 2022;11(1):001–6.CrossRef
23.
go back to reference •• Petrović D, Galić D, Seifert D, Lešić N, Smolić M. Evaluation of bioactive glass treatment for dentin hypersensitivity: a systematic review. Biomedicines. 2023;11(7):1992. A review revealing that at-home or in-office dental applications of CSPS and FCPS at specific concentrations are effective in addressing dentin hypersensitivity in adult individuals.CrossRefPubMedPubMedCentral •• Petrović D, Galić D, Seifert D, Lešić N, Smolić M. Evaluation of bioactive glass treatment for dentin hypersensitivity: a systematic review. Biomedicines. 2023;11(7):1992. A review revealing that at-home or in-office dental applications of CSPS and FCPS at specific concentrations are effective in addressing dentin hypersensitivity in adult individuals.CrossRefPubMedPubMedCentral
24.
go back to reference Loh ZW, Mohd Zaid MH, Awang Kechik MM, Fen YW, Amin KM, Cheong WM. New formulation calcium-based 45S5 bioactive glass: in vitro assessment in PBS solution for potential dental applications. J Mater Res Technol [Internet]. 2023;24:3815–25.CrossRef Loh ZW, Mohd Zaid MH, Awang Kechik MM, Fen YW, Amin KM, Cheong WM. New formulation calcium-based 45S5 bioactive glass: in vitro assessment in PBS solution for potential dental applications. J Mater Res Technol [Internet]. 2023;24:3815–25.CrossRef
25.
go back to reference Hammami I, Gavinho SR, Pádua AS, Lança MdC, Borges JP, Silva JC, et al. Extensive investigation on the effect of niobium insertion on the physical and biological properties of 45s5 bioactive glass for dental implant. Int J Mol Sci. 2023;24(6):5244. https://doi.org/10.3390/ijms24065244. Hammami I, Gavinho SR, Pádua AS, Lança MdC, Borges JP, Silva JC, et al. Extensive investigation on the effect of niobium insertion on the physical and biological properties of 45s5 bioactive glass for dental implant. Int J Mol Sci. 2023;24(6):5244. https://​doi.​org/​10.​3390/​ijms24065244.
26.
go back to reference de Freitas SAA, de Oliveira NMA, de Geus JL, de Souza SFC, de Pereira AFV, Bauer J. Bioactive toothpastes in dentin hypersensitivity treatment: a systematic review. Saudi Dent J. 2021;33(7):395–403.CrossRefPubMedPubMedCentral de Freitas SAA, de Oliveira NMA, de Geus JL, de Souza SFC, de Pereira AFV, Bauer J. Bioactive toothpastes in dentin hypersensitivity treatment: a systematic review. Saudi Dent J. 2021;33(7):395–403.CrossRefPubMedPubMedCentral
29.
go back to reference • Ali S, Farooq I, Al-Thobity AM, Al-Khalifa KS, Alhooshani K, Sauro S. An in-vitro evaluation of fluoride content and enamel remineralization potential of two toothpastes containing different bioactive glasses. Biomed Mater Eng. 2020;30(5–6):487–96. The experimental studies indicated that BiominF® toothpaste exhibited higher fluoride content and a greater capacity to encourage remineralization of demineralized human enamel when compared to Novamin®.PubMed • Ali S, Farooq I, Al-Thobity AM, Al-Khalifa KS, Alhooshani K, Sauro S. An in-vitro evaluation of fluoride content and enamel remineralization potential of two toothpastes containing different bioactive glasses. Biomed Mater Eng. 2020;30(5–6):487–96. The experimental studies indicated that BiominF® toothpaste exhibited higher fluoride content and a greater capacity to encourage remineralization of demineralized human enamel when compared to Novamin®.PubMed
30.
go back to reference Chen X, Wang M, Kenny C, Chen X, Karpukhina N, Hill RG. Novel fluoride- and chloride-containing bioactive glasses for use in air abrasion. J Dent [Internet]. 2022;125(August):104252.CrossRefPubMed Chen X, Wang M, Kenny C, Chen X, Karpukhina N, Hill RG. Novel fluoride- and chloride-containing bioactive glasses for use in air abrasion. J Dent [Internet]. 2022;125(August):104252.CrossRefPubMed
31.
go back to reference Burwell A, Jennings D, Muscle D, Greenspan DC. NovaMin®and dentin hypersensitivity-In vitro evidence of efficacy. J Clin Dent. 2010;21(3):66–71.PubMed Burwell A, Jennings D, Muscle D, Greenspan DC. NovaMin®and dentin hypersensitivity-In vitro evidence of efficacy. J Clin Dent. 2010;21(3):66–71.PubMed
32.
go back to reference •• AS, Al-Harbi N, Al-Hadeethi Y, Abbassy MA, Katturi NK, Xin B, et al. Invitro evaluation of new treatment for dentin hypersensitivity using BioMin F and BioMin C. J Non Cryst Solids [Internet]. 2023;602(June 2022):122072. The experimental study has provided insights into the impact of fluoride- and chloride-containing bioactive glasses in treating dentin hypersensitivity. •• AS, Al-Harbi N, Al-Hadeethi Y, Abbassy MA, Katturi NK, Xin B, et al. Invitro evaluation of new treatment for dentin hypersensitivity using BioMin F and BioMin C. J Non Cryst Solids [Internet]. 2023;602(June 2022):122072. The experimental study has provided insights into the impact of fluoride- and chloride-containing bioactive glasses in treating dentin hypersensitivity.
33.
go back to reference Khijmatgar S, Reddy U, John S, Badavannavar AN, Souza DT. Is there evidence for Novamin application in remineralization?: a systematic review. J Oral Biol Craniofacial Res [Internet]. 2020;10(2):87–92.CrossRef Khijmatgar S, Reddy U, John S, Badavannavar AN, Souza DT. Is there evidence for Novamin application in remineralization?: a systematic review. J Oral Biol Craniofacial Res [Internet]. 2020;10(2):87–92.CrossRef
34.
go back to reference Mohapatra S, Pradeep Kumar R, Meignana Arumugham I, Sri Sakthi D, Jayashri P. Assessment of microhardness of enamel carious like lesions after treatment with nova min, bio min and remin pro containing toothpastes: an in vitro study. Indian J Public Heal Res Dev. 2019;10(10):375–80.CrossRef Mohapatra S, Pradeep Kumar R, Meignana Arumugham I, Sri Sakthi D, Jayashri P. Assessment of microhardness of enamel carious like lesions after treatment with nova min, bio min and remin pro containing toothpastes: an in vitro study. Indian J Public Heal Res Dev. 2019;10(10):375–80.CrossRef
36.
go back to reference •• Mahmoodi B, Goggin P, Fowler C, Cook RB. Quantitative assessment of dentine mineralization and tubule occlusion by NovaMin and stannous fluoride using serial block face scanning electron microscopy. J Biomed Mater Res - Part B Appl Biomater. 2021;109(5):717–22. The enhanced level of tubule occlusion and dentin mineralization achieved with the dentifrice containing NovaMin may offer improved relief and protection against dental hypersensitivity, as assessed quantitatively.CrossRef •• Mahmoodi B, Goggin P, Fowler C, Cook RB. Quantitative assessment of dentine mineralization and tubule occlusion by NovaMin and stannous fluoride using serial block face scanning electron microscopy. J Biomed Mater Res - Part B Appl Biomater. 2021;109(5):717–22. The enhanced level of tubule occlusion and dentin mineralization achieved with the dentifrice containing NovaMin may offer improved relief and protection against dental hypersensitivity, as assessed quantitatively.CrossRef
Metadata
Title
A Review on Enhancing the Life of Teeth by Toothpaste Containing Bioactive Glass Particles
Authors
P. Syam Prasad
Mahammod Babar Pasha
R. Narasimha Rao
P. Venkateswara Rao
Narayanan Madaboosi
Mutlu Özcan
Publication date
16-02-2024
Publisher
Springer International Publishing
Keyword
Caries
Published in
Current Oral Health Reports / Issue 2/2024
Electronic ISSN: 2196-3002
DOI
https://doi.org/10.1007/s40496-024-00366-3

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