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Current Oral Health Reports
Published in: Current Oral Health Reports 4/2020

01-12-2020 | Dental Restorative Materials (M Özcan & P Cesar, Section Editor)

Nile Tilapia Fish Skin, Scales, and Spine as Naturally Derived Biomaterials for Tissue Regeneration

Authors: Maria Elisa Quezado Lima-Verde, S. Prakash Parthiban, Antonio Ernando Carlos Ferreira Junior, Paulo Goberlânio de Barros Silva, Edmar Maciel Lima Junior, Manoel Odorico de Moraes, Vicente de Paulo Aragão Sabóia, Luiz E. Bertassoni, Ana Paula Negreiros Nunes Alves

Published in: Current Oral Health Reports | Issue 4/2020

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Abstract

Purpose of Review

This study aims to review the literature on the use of Nile tilapia-derived extracellular matrix (ECM) proteins as naturally derived scaffold material for tissue regeneration.

Recent Findings

Nile tilapia has emerged as a particularly relevant specie for the development of fish-derived biomaterials. The skin, scale, and spine of various fish species have been extensively demonstrated as a potential source of native ECM proteins for use in regenerative medicine.

Summary

When compared to synthetic polymers, collagen-based biomaterials introduce some disadvantages due to their lower biomechanical stiffness and rapid biodegradation. However, collagen-based biomaterials continue to be one of the most highly investigated natural materials for bone regeneration. Studies have pointed to tilapia as a satisfactory source of collagen for its quality and cost benefit, with good responses in vitro and in vivo, especially studies involving the skin as the main source of production. For both soft and hard tissue regenerations, Nile tilapia skin is being considered as a good source of collagen. Other sources (scales and spine) are less addressed in comparison to skin, which in turn, brings more consistent perspective in relation to clinical use.
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Metadata
Title
Nile Tilapia Fish Skin, Scales, and Spine as Naturally Derived Biomaterials for Tissue Regeneration
Authors
Maria Elisa Quezado Lima-Verde
S. Prakash Parthiban
Antonio Ernando Carlos Ferreira Junior
Paulo Goberlânio de Barros Silva
Edmar Maciel Lima Junior
Manoel Odorico de Moraes
Vicente de Paulo Aragão Sabóia
Luiz E. Bertassoni
Ana Paula Negreiros Nunes Alves
Publication date
01-12-2020
Publisher
Springer International Publishing
Published in
Current Oral Health Reports / Issue 4/2020
Electronic ISSN: 2196-3002
DOI
https://doi.org/10.1007/s40496-020-00286-y

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