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European Archives of Paediatric Dentistry

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Open Access 01-12-2017 | Original Scientific Article

Effects of nicomethanol hydrofluoride on dental enamel and synthetic apatites: a role for anti-caries protection

Author: N. Sharkov

Published in: European Archives of Paediatric Dentistry | Issue 6/2017

Abstract

Aim

To analyse the anti-caries properties of nicomethanol hydrofluoride (NH) and the benefit of its combination with siliglycol, a coating agent.

Methods

Fluoride (F) uptake by dental enamel and synthetic apatite treated with NH was measured in vitro and compared to treatment with mineral fluorides. The addition of siliglycol was also tested. The effect of NH (as a mouthwash) on salivary pH was also investigated in healthy human subjects and compared to the effect of a placebo and of nicomethanol alone.

Results

In vitro experiments showed a greater and faster F uptake on dental enamel or synthetic apatite treated with NH compared to sodium fluoride. F uptake was improved further by the addition of siliglycol. In healthy human subjects, pH reduction was strongly inhibited 5 min after two mouthrinses with NH. This effect was less pronounced but still statistically significant at 15 and 30 min (p < 0.05).

Conclusions

NH was able to promote the fixation of F ions and strengthen the dental structure. Its combination with siliglycol further improved F uptake by the tooth and the control/inhibition of dental biofilm development.

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Title: Effects of nicomethanol hydrofluoride on dental enamel and synthetic apatites: a role for anti-caries protection
Author: N. Sharkov
Publication date: 01-12-2017
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Paediatric Dentistry / Issue 6/2017
Print ISSN: 1818-6300
Electronic ISSN: 1996-9805
DOI: https://doi.org/10.1007/s40368-017-0314-8

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Effects of nicomethanol hydrofluoride on dental enamel and synthetic apatites: a role for anti-caries protection

Abstract

Aim

Methods

Results

Conclusions

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Abstract

Aim

Methods

Results

Conclusions

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