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Pediatric Drugs
Published in: Pediatric Drugs 2/2016

01-04-2016 | Therapy in Practice

Optimizing the Use of Antibacterial Agents in the Neonatal Period

Author: Joseph B. Cantey

Published in: Pediatric Drugs | Issue 2/2016

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Abstract

Antibiotics are invaluable in the management of neonatal infections. However, overuse or misuse of antibiotics in neonates has been associated with adverse outcomes, including increased risk for future infection, necrotizing enterocolitis, and mortality. Strategies to optimize the use of antibiotics in the neonatal intensive care unit include practicing effective infection prevention, improving the diagnostic evaluation and empiric therapy for suspected infections, timely adjustment of therapy as additional information becomes available, and treating proven infections with an effective, narrow-spectrum agent for the minimum effective duration. Antibiotic stewardship programs provide support for these strategies but require the participation and input of neonatologists as stakeholders to be most effective.
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Metadata
Title
Optimizing the Use of Antibacterial Agents in the Neonatal Period
Author
Joseph B. Cantey
Publication date
01-04-2016
Publisher
Springer International Publishing
Published in
Pediatric Drugs / Issue 2/2016
Print ISSN: 1174-5878
Electronic ISSN: 1179-2019
DOI
https://doi.org/10.1007/s40272-015-0161-1

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