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Published in: American Journal of Clinical Dermatology 4/2014

01-08-2014 | Therapy in Practice

A Practical Approach to Cutaneous Sarcoidosis

Authors: Karolyn A. Wanat, Misha Rosenbach

Published in: American Journal of Clinical Dermatology | Issue 4/2014

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Abstract

Sarcoidosis is a chronic inflammatory disorder that has the potential to affect multiple organs, including the skin. Its cutaneous manifestations are varied and can provide clues to underlying systemic manifestations. Unfortunately, they also can be disfiguring. Therapy is usually directed at the organ system most severely affected, which often may help cutaneous disease. However, cutaneous disease may be recalcitrant to treatment directed at extracutaneous disease, or it may be severe enough to require targeted therapy. This article focuses on the dermatologist’s role in recognizing and diagnosing cutaneous sarcoidosis, evaluating patients for systemic disease involvement, and treating the skin manifestations of sarcoidosis.
Literature
1.
go back to reference III Italian Conference on Sarcoidosis and Other Granulomatous Disorders. Padua, April 12–13, 1991. Proceedings and abstracts. Sarcoidosis. 1991;8(2):161–202. III Italian Conference on Sarcoidosis and Other Granulomatous Disorders. Padua, April 12–13, 1991. Proceedings and abstracts. Sarcoidosis. 1991;8(2):161–202.
2.
go back to reference Proceedings of the 1991 XIIth World Congress on Sarcoidosis. Kyoto, Japan, September 8–13, 1991. Sarcoidosis. 1992;9 Suppl 1:1–683. Proceedings of the 1991 XIIth World Congress on Sarcoidosis. Kyoto, Japan, September 8–13, 1991. Sarcoidosis. 1992;9 Suppl 1:1–683.
3.
go back to reference Statement on sarcoidosis. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. Am J Respir Crit Care Med. 1999;160(2):736–55. Statement on sarcoidosis. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. Am J Respir Crit Care Med. 1999;160(2):736–55.
4.
go back to reference Rybicki BA, Iannuzzi MC. Epidemiology of sarcoidosis: recent advances and future prospects. Semin Respir Crit Care Med. 2007;28(1):22–35.PubMed Rybicki BA, Iannuzzi MC. Epidemiology of sarcoidosis: recent advances and future prospects. Semin Respir Crit Care Med. 2007;28(1):22–35.PubMed
5.
go back to reference Rybicki BA, Maliarik MJ, Major M, Popovich J Jr, Iannuzzi MC. Epidemiology, demographics, and genetics of sarcoidosis. Semin Respir Infect. 1998;13(3):166–73.PubMed Rybicki BA, Maliarik MJ, Major M, Popovich J Jr, Iannuzzi MC. Epidemiology, demographics, and genetics of sarcoidosis. Semin Respir Infect. 1998;13(3):166–73.PubMed
6.
go back to reference Rybicki BA, Major M, Popovich J Jr, Maliarik MJ, Iannuzzi MC. Racial differences in sarcoidosis incidence: a 5-year study in a health maintenance organization. Am J Epidemiol. 1997;145(3):234–41.PubMed Rybicki BA, Major M, Popovich J Jr, Maliarik MJ, Iannuzzi MC. Racial differences in sarcoidosis incidence: a 5-year study in a health maintenance organization. Am J Epidemiol. 1997;145(3):234–41.PubMed
7.
go back to reference Morimoto T, Azuma A, Abe S, Usuki J, Kudoh S, Sugisaki K, et al. Epidemiology of sarcoidosis in Japan. Eur Respiratory J. 2008;31(2):372–9. Morimoto T, Azuma A, Abe S, Usuki J, Kudoh S, Sugisaki K, et al. Epidemiology of sarcoidosis in Japan. Eur Respiratory J. 2008;31(2):372–9.
8.
go back to reference Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part I. Cutaneous disease. J Am Acad Dermatol. 2012;66(5):699 e1–18; quiz 717–8. Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part I. Cutaneous disease. J Am Acad Dermatol. 2012;66(5):699 e1–18; quiz 717–8.
9.
go back to reference Noor A, Knox KS. Immunopathogenesis of sarcoidosis. Clin Dermatol. 2007;25(3):250–8. Noor A, Knox KS. Immunopathogenesis of sarcoidosis. Clin Dermatol. 2007;25(3):250–8.
10.
go back to reference Iannuzzi MC, Fontana JR. Sarcoidosis: clinical presentation, immunopathogenesis, and therapeutics. JAMA. 2011;305(4):391–9.PubMed Iannuzzi MC, Fontana JR. Sarcoidosis: clinical presentation, immunopathogenesis, and therapeutics. JAMA. 2011;305(4):391–9.PubMed
11.
go back to reference Iannuzzi MC, Rybicki BA, Teirstein AS. Sarcoidosis. New Engl J Med. 2007;357(21):2153–65.PubMed Iannuzzi MC, Rybicki BA, Teirstein AS. Sarcoidosis. New Engl J Med. 2007;357(21):2153–65.PubMed
12.
go back to reference Chen ES, Moller DR. Sarcoidosis—scientific progress and clinical challenges. Nat Rev Rheumatol. 2011;7(8):457–67.PubMed Chen ES, Moller DR. Sarcoidosis—scientific progress and clinical challenges. Nat Rev Rheumatol. 2011;7(8):457–67.PubMed
13.
go back to reference Rossman MD, Thompson B, Frederick M, Iannuzzi MC, Rybicki BA, Pander JP, et al. HLA and environmental interactions in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2008;25(2):125–32.PubMed Rossman MD, Thompson B, Frederick M, Iannuzzi MC, Rybicki BA, Pander JP, et al. HLA and environmental interactions in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2008;25(2):125–32.PubMed
14.
go back to reference Iannuzzi MC, Iyengar SK, Gray-McGuire C, Elston RC, Baughman RP, Donohue JF, et al. Genome-wide search for sarcoidosis susceptibility genes in African Americans. Genes Immun. 2005;6(6):509–18.PubMed Iannuzzi MC, Iyengar SK, Gray-McGuire C, Elston RC, Baughman RP, Donohue JF, et al. Genome-wide search for sarcoidosis susceptibility genes in African Americans. Genes Immun. 2005;6(6):509–18.PubMed
15.
go back to reference Hofmann S, Fischer A, Nothnagel M, Jacobs G, Schmid B, Wittig M, et al. Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis. Eur Respir J. 2013;41(4):888–900.PubMed Hofmann S, Fischer A, Nothnagel M, Jacobs G, Schmid B, Wittig M, et al. Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis. Eur Respir J. 2013;41(4):888–900.PubMed
16.
go back to reference Spagnolo P, Schwartz DA. Genetic predisposition to sarcoidosis: another brick in the wall. Eur Respir J. 2013;41(4):778–80.PubMed Spagnolo P, Schwartz DA. Genetic predisposition to sarcoidosis: another brick in the wall. Eur Respir J. 2013;41(4):778–80.PubMed
17.
go back to reference Franke A, Fischer A, Nothnagel M, Becker C, Grabe N, Till A, et al. Genome-wide association analysis in sarcoidosis and Crohn’s disease unravels a common susceptibility locus on 10p12.2. Gastroenterology. 2008;135(4):1207–15.PubMed Franke A, Fischer A, Nothnagel M, Becker C, Grabe N, Till A, et al. Genome-wide association analysis in sarcoidosis and Crohn’s disease unravels a common susceptibility locus on 10p12.2. Gastroenterology. 2008;135(4):1207–15.PubMed
18.
go back to reference Newman KL, Newman LS. Occupational causes of sarcoidosis. Curr Opin Allergy Clin Immunol. 2012;12(2):145–50.PubMed Newman KL, Newman LS. Occupational causes of sarcoidosis. Curr Opin Allergy Clin Immunol. 2012;12(2):145–50.PubMed
19.
go back to reference Reich JM. Sarcoidosis and World Trade Center disaster. J Occup Environ Med. 2012;54(1):2; author reply -3. Reich JM. Sarcoidosis and World Trade Center disaster. J Occup Environ Med. 2012;54(1):2; author reply -3.
20.
go back to reference Gupta D, Agarwal R, Aggarwal AN, Jindal SK. Molecular evidence for the role of mycobacteria in sarcoidosis: a meta-analysis. Eur Respir J. 2007;30(3):508–16.PubMed Gupta D, Agarwal R, Aggarwal AN, Jindal SK. Molecular evidence for the role of mycobacteria in sarcoidosis: a meta-analysis. Eur Respir J. 2007;30(3):508–16.PubMed
21.
go back to reference Rutherford RM, Gilmartin JJ. Mycobacteria in pathogenesis of sarcoidosis. Chest. 2004;125(1):354.PubMed Rutherford RM, Gilmartin JJ. Mycobacteria in pathogenesis of sarcoidosis. Chest. 2004;125(1):354.PubMed
22.
go back to reference Brownell I, Ramirez-Valle F, Sanchez M, Prystowsky S. Evidence for mycobacteria in sarcoidosis. Am J Respir Cell Mol Biol. 2011;45(5):899–905.PubMedCentralPubMed Brownell I, Ramirez-Valle F, Sanchez M, Prystowsky S. Evidence for mycobacteria in sarcoidosis. Am J Respir Cell Mol Biol. 2011;45(5):899–905.PubMedCentralPubMed
23.
go back to reference Oswald-Richter KA, Beachboard DC, Seeley EH, Abraham S, Shepherd BE, Jenkins CA, et al. Dual analysis for mycobacteria and propionibacteria in sarcoidosis BAL. J Clin Immunol. 2012;32(5):1129–40.PubMedCentralPubMed Oswald-Richter KA, Beachboard DC, Seeley EH, Abraham S, Shepherd BE, Jenkins CA, et al. Dual analysis for mycobacteria and propionibacteria in sarcoidosis BAL. J Clin Immunol. 2012;32(5):1129–40.PubMedCentralPubMed
24.
go back to reference Furusawa H, Suzuki Y, Miyazaki Y, Inase N, Eishi Y. Th1 and Th17 immune responses to viable Propionibacterium acnes in patients with sarcoidosis. Respir Investig. 2012;50(3):104–9.PubMed Furusawa H, Suzuki Y, Miyazaki Y, Inase N, Eishi Y. Th1 and Th17 immune responses to viable Propionibacterium acnes in patients with sarcoidosis. Respir Investig. 2012;50(3):104–9.PubMed
25.
go back to reference Chen ES, Song Z, Willett MH, Heine S, Yung RC, Liu MC, et al. Serum amyloid A regulates granulomatous inflammation in sarcoidosis through Toll-like receptor-2. Am J Respir Crit Care Med. 2010;181(4):360–73.PubMedCentralPubMed Chen ES, Song Z, Willett MH, Heine S, Yung RC, Liu MC, et al. Serum amyloid A regulates granulomatous inflammation in sarcoidosis through Toll-like receptor-2. Am J Respir Crit Care Med. 2010;181(4):360–73.PubMedCentralPubMed
26.
go back to reference Parisinos CA. Sarcoidosis is a Th1/Th17 multisystem disorder: wider implications. Thorax. 2011;66(11):1011–2; author reply 1012. Parisinos CA. Sarcoidosis is a Th1/Th17 multisystem disorder: wider implications. Thorax. 2011;66(11):1011–2; author reply 1012.
27.
go back to reference Zissel G, Prasse A, Muller-Quernheim J. Sarcoidosis—immunopathogenetic concepts. Semin Respir Crit Care Med. 2007;28(1):3–14.PubMed Zissel G, Prasse A, Muller-Quernheim J. Sarcoidosis—immunopathogenetic concepts. Semin Respir Crit Care Med. 2007;28(1):3–14.PubMed
28.
go back to reference Zissel G, Prasse A, Muller-Quernheim J. Immunologic response of sarcoidosis. Semin Respir Crit Care Med. 2010;31(4):390–403.PubMed Zissel G, Prasse A, Muller-Quernheim J. Immunologic response of sarcoidosis. Semin Respir Crit Care Med. 2010;31(4):390–403.PubMed
29.
go back to reference Facco M, Cabrelle A, Teramo A, Olivieri V, Gnoato M, Teolato S, et al. Sarcoidosis is a Th1/Th17 multisystem disorder. Thorax. 2011;66(2):144–50.PubMed Facco M, Cabrelle A, Teramo A, Olivieri V, Gnoato M, Teolato S, et al. Sarcoidosis is a Th1/Th17 multisystem disorder. Thorax. 2011;66(2):144–50.PubMed
30.
go back to reference Huang H, Lu Z, Jiang C, Liu J, Wang Y, Xu Z. Imbalance between Th17 and regulatory T-Cells in sarcoidosis. Int J Mol Sci. 2013;14(11):21463–73.PubMedCentralPubMed Huang H, Lu Z, Jiang C, Liu J, Wang Y, Xu Z. Imbalance between Th17 and regulatory T-Cells in sarcoidosis. Int J Mol Sci. 2013;14(11):21463–73.PubMedCentralPubMed
31.
go back to reference Ten Berge B, Paats MS, Bergen IM, van den Blink B, Hoogsteden HC, Lambrecht BN, et al. Increased IL-17A expression in granulomas and in circulating memory T cells in sarcoidosis. Rheumatology. 2012;51(1):37–46.PubMed Ten Berge B, Paats MS, Bergen IM, van den Blink B, Hoogsteden HC, Lambrecht BN, et al. Increased IL-17A expression in granulomas and in circulating memory T cells in sarcoidosis. Rheumatology. 2012;51(1):37–46.PubMed
32.
go back to reference Urbankowski T, Hoser G, Domagala-Kulawik J. Th1/Th2/Th17 related cytokines in the bronchoalveolar lavage fluid of patients with sarcoidosis: association with smoking. Pol Arch Med Wewn. 2012;122(7–8):320–5.PubMed Urbankowski T, Hoser G, Domagala-Kulawik J. Th1/Th2/Th17 related cytokines in the bronchoalveolar lavage fluid of patients with sarcoidosis: association with smoking. Pol Arch Med Wewn. 2012;122(7–8):320–5.PubMed
33.
go back to reference Kim HS, Choi D, Lim LL, Allada G, Smith JR, Austin CR, et al. Association of interleukin 23 receptor gene with sarcoidosis. Dis Markers. 2011;31(1):17–24.PubMedCentralPubMed Kim HS, Choi D, Lim LL, Allada G, Smith JR, Austin CR, et al. Association of interleukin 23 receptor gene with sarcoidosis. Dis Markers. 2011;31(1):17–24.PubMedCentralPubMed
34.
go back to reference Schurmann M, Kwiatkowski R, Albrecht M, Fischer A, Hampe J, Muller-Quernheim J, et al. Study of Toll-like receptor gene loci in sarcoidosis. Clin Exp Immunol. 2008;152(3):423–31.PubMedCentralPubMed Schurmann M, Kwiatkowski R, Albrecht M, Fischer A, Hampe J, Muller-Quernheim J, et al. Study of Toll-like receptor gene loci in sarcoidosis. Clin Exp Immunol. 2008;152(3):423–31.PubMedCentralPubMed
35.
go back to reference Veltkamp M, Van Moorsel CH, Rijkers GT, Ruven HJ, Van Den Bosch JM, Grutters JC. Toll-like receptor (TLR)-9 genetics and function in sarcoidosis. Clin Exp Immunol. 2010;162(1):68–74.PubMedCentralPubMed Veltkamp M, Van Moorsel CH, Rijkers GT, Ruven HJ, Van Den Bosch JM, Grutters JC. Toll-like receptor (TLR)-9 genetics and function in sarcoidosis. Clin Exp Immunol. 2010;162(1):68–74.PubMedCentralPubMed
36.
go back to reference Richmond BW, Drake WP. Vitamin D innate immunity, and sarcoidosis granulomatous inflammation: insights from mycobacterial research. Curr Opin Pulm Med. 2010;16(5):461–4.PubMed Richmond BW, Drake WP. Vitamin D innate immunity, and sarcoidosis granulomatous inflammation: insights from mycobacterial research. Curr Opin Pulm Med. 2010;16(5):461–4.PubMed
37.
go back to reference Gazouli M, Koundourakis A, Ikonomopoulos J, Gialafos EJ, Rapti A, Gorgoulis VG, et al. CARD15/NOD2, CD14, and Toll-like receptor 4 gene polymorphisms in Greek patients with sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2006;23(1):23–9.PubMed Gazouli M, Koundourakis A, Ikonomopoulos J, Gialafos EJ, Rapti A, Gorgoulis VG, et al. CARD15/NOD2, CD14, and Toll-like receptor 4 gene polymorphisms in Greek patients with sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2006;23(1):23–9.PubMed
38.
go back to reference Marinis JM, Homer CR, McDonald C, Abbott DW. A novel motif in the Crohn’s disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses. J Biol Chem. 2011;286(3):1938–50.PubMedCentralPubMed Marinis JM, Homer CR, McDonald C, Abbott DW. A novel motif in the Crohn’s disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses. J Biol Chem. 2011;286(3):1938–50.PubMedCentralPubMed
39.
go back to reference Culver DA, Newman LS, Kavuru MS. Gene-environment interactions in sarcoidosis: challenge and opportunity. Clin Dermatol. 2007;25(3):267–75. Culver DA, Newman LS, Kavuru MS. Gene-environment interactions in sarcoidosis: challenge and opportunity. Clin Dermatol. 2007;25(3):267–75.
40.
go back to reference Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part II. Extracutaneous disease. J Am Acad Dermatol. 2012;66(5):719 e1–10; quiz 729–30. Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part II. Extracutaneous disease. J Am Acad Dermatol. 2012;66(5):719 e1–10; quiz 729–30.
41.
go back to reference Baughman RP, Teirstein AS, Judson MA, Rossman MD, Yeager H Jr, Bresnitz EA, et al. Clinical characteristics of patients in a case control study of sarcoidosis. Am J Respir Crit Care Med. 2001;164(10 Pt 1):1885–9.PubMed Baughman RP, Teirstein AS, Judson MA, Rossman MD, Yeager H Jr, Bresnitz EA, et al. Clinical characteristics of patients in a case control study of sarcoidosis. Am J Respir Crit Care Med. 2001;164(10 Pt 1):1885–9.PubMed
42.
go back to reference Nozaki K, Judson MA. Neurosarcoidosis: clinical manifestations, diagnosis and treatment. Presse Med. 2012;41(6 Pt 2):e331–48.PubMed Nozaki K, Judson MA. Neurosarcoidosis: clinical manifestations, diagnosis and treatment. Presse Med. 2012;41(6 Pt 2):e331–48.PubMed
43.
go back to reference Berliner AR, Haas M, Choi MJ. Sarcoidosis: the nephrologist’s perspective. Am J Kidney Dis. 2006;48(5):856–70.PubMed Berliner AR, Haas M, Choi MJ. Sarcoidosis: the nephrologist’s perspective. Am J Kidney Dis. 2006;48(5):856–70.PubMed
44.
go back to reference Mantini N, Williams B Jr, Stewart J, Rubinsztain L, Kacharava A. Cardiac sarcoid: a clinician’s review on how to approach the patient with cardiac sarcoid. Clin Cardiol. 2012;35(7):410–5.PubMed Mantini N, Williams B Jr, Stewart J, Rubinsztain L, Kacharava A. Cardiac sarcoid: a clinician’s review on how to approach the patient with cardiac sarcoid. Clin Cardiol. 2012;35(7):410–5.PubMed
45.
go back to reference Kim JS, Judson MA, Donnino R, Gold M, Cooper LT Jr, Prystowsky EN, et al. Cardiac sarcoidosis. Am Heart J. 2009;157(1):9–21.PubMed Kim JS, Judson MA, Donnino R, Gold M, Cooper LT Jr, Prystowsky EN, et al. Cardiac sarcoidosis. Am Heart J. 2009;157(1):9–21.PubMed
46.
go back to reference English JC 3rd, Patel PJ, Greer KE. Sarcoidosis. J Am Acad Dermatol. 2001;44(5):725–43; quiz 744–6. English JC 3rd, Patel PJ, Greer KE. Sarcoidosis. J Am Acad Dermatol. 2001;44(5):725–43; quiz 744–6.
47.
go back to reference Newman LS, Rose CS, Maier LA. Sarcoidosis. New Engl J Med. 1997;336(17):1224–34.PubMed Newman LS, Rose CS, Maier LA. Sarcoidosis. New Engl J Med. 1997;336(17):1224–34.PubMed
49.
go back to reference Marchell RM, Judson MA. Cutaneous sarcoidosis. Semin Respir Crit Care Med. 2010;31(4):442–51.PubMed Marchell RM, Judson MA. Cutaneous sarcoidosis. Semin Respir Crit Care Med. 2010;31(4):442–51.PubMed
50.
go back to reference Marchell RM, Judson MA. Chronic cutaneous lesions of sarcoidosis. Clin Dermatol. 2007;25(3):295–302. Marchell RM, Judson MA. Chronic cutaneous lesions of sarcoidosis. Clin Dermatol. 2007;25(3):295–302.
51.
go back to reference Mana J, Marcoval J. Skin manifestations of sarcoidosis. Presse Med. 2012;41(6 Pt 2):e355–74.PubMed Mana J, Marcoval J. Skin manifestations of sarcoidosis. Presse Med. 2012;41(6 Pt 2):e355–74.PubMed
52.
go back to reference Marcoval J, Mana J, Rubio M. Specific cutaneous lesions in patients with systemic sarcoidosis: relationship to severity and chronicity of disease. Clin Exp Dermatol. 2011;36(7):739–44.PubMed Marcoval J, Mana J, Rubio M. Specific cutaneous lesions in patients with systemic sarcoidosis: relationship to severity and chronicity of disease. Clin Exp Dermatol. 2011;36(7):739–44.PubMed
53.
go back to reference Higgins EM, Salisbury JR, Du Vivier AW. Subcutaneous sarcoidosis. Clin Exp Dermatol. 1993;18(1):65–6.PubMed Higgins EM, Salisbury JR, Du Vivier AW. Subcutaneous sarcoidosis. Clin Exp Dermatol. 1993;18(1):65–6.PubMed
54.
go back to reference Ahmed I, Harshad SR. Subcutaneous sarcoidosis: is it a specific subset of cutaneous sarcoidosis frequently associated with systemic disease? J Am Acad Dermatol. 2006;54(1):55–60.PubMed Ahmed I, Harshad SR. Subcutaneous sarcoidosis: is it a specific subset of cutaneous sarcoidosis frequently associated with systemic disease? J Am Acad Dermatol. 2006;54(1):55–60.PubMed
55.
go back to reference El Sayed F, Dhaybi R, Ammoury A. Subcutaneous nodular sarcoidosis and systemic involvement successfully treated with doxycycline. Leban Med J. 2006;54(1):42–4. El Sayed F, Dhaybi R, Ammoury A. Subcutaneous nodular sarcoidosis and systemic involvement successfully treated with doxycycline. Leban Med J. 2006;54(1):42–4.
56.
go back to reference Marcoval J, Moreno A, Mana J, Peyri J. Subcutaneous sarcoidosis. Dermatol Clin. 2008;26(4):553–6, ix. Marcoval J, Moreno A, Mana J, Peyri J. Subcutaneous sarcoidosis. Dermatol Clin. 2008;26(4):553–6, ix.
57.
go back to reference Dalle Vedove C, Colato C, Girolomoni G. Subcutaneous sarcoidosis: report of two cases and review of the literature. Clin Rheumatol. 2011;30(8):1123–8. Dalle Vedove C, Colato C, Girolomoni G. Subcutaneous sarcoidosis: report of two cases and review of the literature. Clin Rheumatol. 2011;30(8):1123–8.
58.
go back to reference Meyer-Gonzalez T, Suarez-Perez JA, Lopez-Navarro N, Hidalgo A, Herrera-Ceballos E. Subcutaneous sarcoidosis: a predictor of systemic disease? Eur J Intern Med. 2011;22(6):e162–3.PubMed Meyer-Gonzalez T, Suarez-Perez JA, Lopez-Navarro N, Hidalgo A, Herrera-Ceballos E. Subcutaneous sarcoidosis: a predictor of systemic disease? Eur J Intern Med. 2011;22(6):e162–3.PubMed
59.
go back to reference Yanardag H, Pamuk ON, Pamuk GE. Lupus pernio in sarcoidosis: clinical features and treatment outcomes of 14 patients. J Clin Rheumatol. 2003;9(2):72–6.PubMed Yanardag H, Pamuk ON, Pamuk GE. Lupus pernio in sarcoidosis: clinical features and treatment outcomes of 14 patients. J Clin Rheumatol. 2003;9(2):72–6.PubMed
60.
go back to reference Spiteri MA, Matthey F, Gordon T, Carstairs LS, James DG. Lupus pernio: a clinico-radiological study of thirty-five cases. Br J Dermatol. 1985;112(3):315–22.PubMed Spiteri MA, Matthey F, Gordon T, Carstairs LS, James DG. Lupus pernio: a clinico-radiological study of thirty-five cases. Br J Dermatol. 1985;112(3):315–22.PubMed
61.
go back to reference Elgart ML. Cutaneous sarcoidosis: definitions and types of lesions. Clin Dermatol. 1986;4(4):35–45. Elgart ML. Cutaneous sarcoidosis: definitions and types of lesions. Clin Dermatol. 1986;4(4):35–45.
62.
go back to reference Elgart ML. Cutaneous lesions of sarcoidosis. Prim Care. 1978;5(2):249–62.PubMed Elgart ML. Cutaneous lesions of sarcoidosis. Prim Care. 1978;5(2):249–62.PubMed
63.
go back to reference Efthimiou P, Kukar M. Lupus pernio: sarcoid-specific cutaneous manifestation associated with chronic sarcoid arthropathy. J Clin Rheumatol. 2011;17(6):343.PubMed Efthimiou P, Kukar M. Lupus pernio: sarcoid-specific cutaneous manifestation associated with chronic sarcoid arthropathy. J Clin Rheumatol. 2011;17(6):343.PubMed
64.
go back to reference Neville E, Mills RG, Jash DK, Mackinnon DM, Carstairs LS, James DG. Sarcoidosis of the upper respiratory tract and its association with lupus pernio. Thorax. 1976;31(6):660–4.PubMedCentralPubMed Neville E, Mills RG, Jash DK, Mackinnon DM, Carstairs LS, James DG. Sarcoidosis of the upper respiratory tract and its association with lupus pernio. Thorax. 1976;31(6):660–4.PubMedCentralPubMed
66.
go back to reference Baughman RP, Judson MA, Teirstein A, Lower EE, Lo K, Schlenker-Herceg R, et al. Chronic facial sarcoidosis including lupus pernio: clinical description and proposed scoring systems. Am J Clin Dermatol. 2008;9(3):155–61.PubMed Baughman RP, Judson MA, Teirstein A, Lower EE, Lo K, Schlenker-Herceg R, et al. Chronic facial sarcoidosis including lupus pernio: clinical description and proposed scoring systems. Am J Clin Dermatol. 2008;9(3):155–61.PubMed
67.
go back to reference Grema H, Greve B, Raulin C. Scar sarcoidosis—treatment with the Q-switched ruby laser. Lasers Surg Med. 2002;30(5):398–400.PubMed Grema H, Greve B, Raulin C. Scar sarcoidosis—treatment with the Q-switched ruby laser. Lasers Surg Med. 2002;30(5):398–400.PubMed
68.
go back to reference Holzmann RD, Astner S, Forschner T, Sterry G. Scar sarcoidosis in a child: case report of successful treatment with the pulsed dye laser. Dermatol Surg. 2008;34(3):393–6.PubMed Holzmann RD, Astner S, Forschner T, Sterry G. Scar sarcoidosis in a child: case report of successful treatment with the pulsed dye laser. Dermatol Surg. 2008;34(3):393–6.PubMed
69.
go back to reference House NS, Welsh JP, English JC 3rd. Sarcoidosis-induced alopecia. Dermatol Online J. 2012;18(8):4.PubMed House NS, Welsh JP, English JC 3rd. Sarcoidosis-induced alopecia. Dermatol Online J. 2012;18(8):4.PubMed
70.
go back to reference Douri T, Chawaf AZ, Alrefaee BA. Cicatricial alopecia due to sarcoidosis. Dermatol Online J. 2003;9(1):16.PubMed Douri T, Chawaf AZ, Alrefaee BA. Cicatricial alopecia due to sarcoidosis. Dermatol Online J. 2003;9(1):16.PubMed
71.
go back to reference Cho HR, Shah A, Hadi S. Systemic sarcoidosis presenting with alopecia of the scalp. Int J Dermatol. 2004;43(7):520–2.PubMed Cho HR, Shah A, Hadi S. Systemic sarcoidosis presenting with alopecia of the scalp. Int J Dermatol. 2004;43(7):520–2.PubMed
72.
go back to reference Sakemi H, Oiwa H. Psoriasiform plaques of sarcoidosis. Internal Med. 2009;48(5):391. Sakemi H, Oiwa H. Psoriasiform plaques of sarcoidosis. Internal Med. 2009;48(5):391.
73.
go back to reference Mittal RR, Singh SP, Gill SS. Psoriasiform sarcoidosis associated with depigmentation. Indian J Dermatol Venereol Leprol. 1996;62(2):103–5. Mittal RR, Singh SP, Gill SS. Psoriasiform sarcoidosis associated with depigmentation. Indian J Dermatol Venereol Leprol. 1996;62(2):103–5.
74.
go back to reference Mitsuishi T, Nogita T, Kawashima M. Psoriasiform sarcoidosis with ulceration. Int J Dermatol. 1992;31(5):339–40.PubMed Mitsuishi T, Nogita T, Kawashima M. Psoriasiform sarcoidosis with ulceration. Int J Dermatol. 1992;31(5):339–40.PubMed
75.
76.
go back to reference Ichiki Y, Kitajima Y. Ulcerative sarcoidosis: case report and review of the Japanese literature. Acta Dermato-Venereol. 2008;88(5):526–8. Ichiki Y, Kitajima Y. Ulcerative sarcoidosis: case report and review of the Japanese literature. Acta Dermato-Venereol. 2008;88(5):526–8.
77.
go back to reference Hunt RD, Gonzalez ME, Robinson M, Meehan SA, Franks AG Jr. Ulcerative sarcoidosis. Dermatol Online J. 2012;18(12):29.PubMed Hunt RD, Gonzalez ME, Robinson M, Meehan SA, Franks AG Jr. Ulcerative sarcoidosis. Dermatol Online J. 2012;18(12):29.PubMed
78.
go back to reference Zhang H, Ma HJ, Liu W, Yuan XY. Sarcoidosis characterized as acquired ichthyosiform erythroderma. Eur J Dermatol. 2009;19(5):516–7. Zhang H, Ma HJ, Liu W, Yuan XY. Sarcoidosis characterized as acquired ichthyosiform erythroderma. Eur J Dermatol. 2009;19(5):516–7.
79.
go back to reference Vasaghi A, Kalafi A. Unusual manifestation of cutaneous sarcoidosis: a case report of morpheaform sarcoidosis. Acta Med Iran. 2012;50(9):648–51.PubMed Vasaghi A, Kalafi A. Unusual manifestation of cutaneous sarcoidosis: a case report of morpheaform sarcoidosis. Acta Med Iran. 2012;50(9):648–51.PubMed
80.
go back to reference Kelley BP, George DE, LeLeux TM, Hsu S. Ichthyosiform sarcoidosis: a case report and review of the literature. Dermatol Online J. 2010;16(8):5.PubMed Kelley BP, George DE, LeLeux TM, Hsu S. Ichthyosiform sarcoidosis: a case report and review of the literature. Dermatol Online J. 2010;16(8):5.PubMed
81.
go back to reference Gangopadhyay AK. Ichthyosiform sarcoidosis. Indian J Dermatol Venereol Leprol. 2001;67(2):91–2. Gangopadhyay AK. Ichthyosiform sarcoidosis. Indian J Dermatol Venereol Leprol. 2001;67(2):91–2.
82.
go back to reference Rampin L, Musto A, Marzola MC, Tadayyon S, Ferretti A, Chondrogiannis S, et al. Diagnosis of unknown sarcoidosis associated to erythema nodosum with 18F-FDG PET/CT. Revista Espanola de Medicina Nuclear e Imagen Mol. 2013;32(3):190–2. Rampin L, Musto A, Marzola MC, Tadayyon S, Ferretti A, Chondrogiannis S, et al. Diagnosis of unknown sarcoidosis associated to erythema nodosum with 18F-FDG PET/CT. Revista Espanola de Medicina Nuclear e Imagen Mol. 2013;32(3):190–2.
83.
go back to reference Ohta H, Tazawa R, Nakamura A, Kimura Y, Maemondo M, Kikuchi T, et al. Acute-onset sarcoidosis with erythema nodosum and polyarthralgia (Lofgren’s syndrome) in Japan: a case report and a review of the literature. Intern Med. 2006;45(9):659–62.PubMed Ohta H, Tazawa R, Nakamura A, Kimura Y, Maemondo M, Kikuchi T, et al. Acute-onset sarcoidosis with erythema nodosum and polyarthralgia (Lofgren’s syndrome) in Japan: a case report and a review of the literature. Intern Med. 2006;45(9):659–62.PubMed
84.
go back to reference O’Connor TM, Cagney D, Jahangir A, Brady A, Fitzgibbon J, Lee G, et al. Characteristics of patients presenting with erythema nodosum and sarcoidosis. Ir Med J. 2009;102(6):181–4.PubMed O’Connor TM, Cagney D, Jahangir A, Brady A, Fitzgibbon J, Lee G, et al. Characteristics of patients presenting with erythema nodosum and sarcoidosis. Ir Med J. 2009;102(6):181–4.PubMed
85.
go back to reference Donmez S, Kisacik B, Pamuk ON, Pehlivan Y, Aydogdu E, Yurekli OA, et al. Are clinical features in Lofgren’s syndrome-related erythema nodosum different from idiopathic erythema nodosum? Sarcoidosis Vasc Diffuse Lung Dis. 2012;29(2):128–31.PubMed Donmez S, Kisacik B, Pamuk ON, Pehlivan Y, Aydogdu E, Yurekli OA, et al. Are clinical features in Lofgren’s syndrome-related erythema nodosum different from idiopathic erythema nodosum? Sarcoidosis Vasc Diffuse Lung Dis. 2012;29(2):128–31.PubMed
86.
go back to reference Hillerdal G, Nou E, Osterman K, Schmekel B. Sarcoidosis: epidemiology and prognosis. A 15-year European study. Am Rev Respir Dis. 1984;130(1):29–32.PubMed Hillerdal G, Nou E, Osterman K, Schmekel B. Sarcoidosis: epidemiology and prognosis. A 15-year European study. Am Rev Respir Dis. 1984;130(1):29–32.PubMed
87.
go back to reference Pietinalho A, Ohmichi M, Hiraga Y, Lofroos AB, Selroos O. The mode of presentation of sarcoidosis in Finland and Hokkaido, Japan. A comparative analysis of 571 Finnish and 686 Japanese patients. Sarcoidosis Vasc Diffuse Lung Dis. 1996;13(2):159–66. Pietinalho A, Ohmichi M, Hiraga Y, Lofroos AB, Selroos O. The mode of presentation of sarcoidosis in Finland and Hokkaido, Japan. A comparative analysis of 571 Finnish and 686 Japanese patients. Sarcoidosis Vasc Diffuse Lung Dis. 1996;13(2):159–66.
88.
go back to reference Judson MA. The diagnosis of sarcoidosis. Clin Chest Med. 2008;29(3):415–27, viii. Judson MA. The diagnosis of sarcoidosis. Clin Chest Med. 2008;29(3):415–27, viii.
89.
go back to reference Ivemark BI. Observations on the histopathology of sarcoidosis. Acta Med Scand Suppl. 1956;312:438–42.PubMed Ivemark BI. Observations on the histopathology of sarcoidosis. Acta Med Scand Suppl. 1956;312:438–42.PubMed
90.
go back to reference Takahashi M. Histopathology of sarcoidosis and its immunological bases. Acta Pathol Jpn. 1970;20(2):171–82.PubMed Takahashi M. Histopathology of sarcoidosis and its immunological bases. Acta Pathol Jpn. 1970;20(2):171–82.PubMed
91.
go back to reference Marcoval J, Mana J, Moreno A, Gallego I, Fortuno Y, Peyri J. Foreign bodies in granulomatous cutaneous lesions of patients with systemic sarcoidosis. Arch Dermatol. 2001;137(4):427–30.PubMed Marcoval J, Mana J, Moreno A, Gallego I, Fortuno Y, Peyri J. Foreign bodies in granulomatous cutaneous lesions of patients with systemic sarcoidosis. Arch Dermatol. 2001;137(4):427–30.PubMed
92.
go back to reference Costabel U, Guzman J, Baughman RP. Systemic evaluation of a potential cutaneous sarcoidosis patient. Clin Dermatol. 2007;25(3):303–11. Costabel U, Guzman J, Baughman RP. Systemic evaluation of a potential cutaneous sarcoidosis patient. Clin Dermatol. 2007;25(3):303–11.
93.
go back to reference Costabel U, Hunninghake GW. ATS/ERS/WASOG statement on sarcoidosis. Sarcoidosis Statement Committee. American Thoracic Society. European Respiratory Society. World Association for Sarcoidosis and Other Granulomatous Disorders. Eur Respir J. 1999;14(4):735–7.PubMed Costabel U, Hunninghake GW. ATS/ERS/WASOG statement on sarcoidosis. Sarcoidosis Statement Committee. American Thoracic Society. European Respiratory Society. World Association for Sarcoidosis and Other Granulomatous Disorders. Eur Respir J. 1999;14(4):735–7.PubMed
94.
go back to reference Bodaghi B, Touitou V, Fardeau C, Chapelon C, LeHoang P. Ocular sarcoidosis. Presse Med. 2012;41(6 Pt 2):e349–54.PubMed Bodaghi B, Touitou V, Fardeau C, Chapelon C, LeHoang P. Ocular sarcoidosis. Presse Med. 2012;41(6 Pt 2):e349–54.PubMed
96.
go back to reference Dubrey SW, Falk RH. Diagnosis and management of cardiac sarcoidosis. Prog Cardiovasc Dis. 2010;52(4):336–46. Dubrey SW, Falk RH. Diagnosis and management of cardiac sarcoidosis. Prog Cardiovasc Dis. 2010;52(4):336–46.
97.
go back to reference Chapelon-Abric C. Cardiac sarcoidosis. Curr Opin Pulm Med. 2013;19(5):493–502.PubMed Chapelon-Abric C. Cardiac sarcoidosis. Curr Opin Pulm Med. 2013;19(5):493–502.PubMed
98.
go back to reference Martusewicz-Boros MM, Piotrowska-Kownacka D, Domagala J, Kowalewski M, Wiatr E. Cardiac sarcoidosis mimicking ischaemic infarct. Kardiol Pol. 2014;72(1):86.PubMed Martusewicz-Boros MM, Piotrowska-Kownacka D, Domagala J, Kowalewski M, Wiatr E. Cardiac sarcoidosis mimicking ischaemic infarct. Kardiol Pol. 2014;72(1):86.PubMed
99.
go back to reference Nakamura S, Hashimoto Y, Nishi K, Takeda K, Mizumoto T, Demitsu T, et al. High rate of cardiac sarcoidosis presenting with cutaneous plaque type sarcoidosis in 18F-fluorodeoxyglucose positron emission tomography-computed tomography: a case series. J Med Case Rep. 2014;8(1):17.PubMedCentralPubMed Nakamura S, Hashimoto Y, Nishi K, Takeda K, Mizumoto T, Demitsu T, et al. High rate of cardiac sarcoidosis presenting with cutaneous plaque type sarcoidosis in 18F-fluorodeoxyglucose positron emission tomography-computed tomography: a case series. J Med Case Rep. 2014;8(1):17.PubMedCentralPubMed
100.
go back to reference Rosenbach M. Practice gaps. The dermatologist’s role in sarcoidosis. JAMA Dermatol. 2013;149(6):760–1. Rosenbach M. Practice gaps. The dermatologist’s role in sarcoidosis. JAMA Dermatol. 2013;149(6):760–1.
101.
go back to reference Anolik RB, Schaffer A, Kim EJ, Rosenbach M. Thyroid dysfunction and cutaneous sarcoidosis. J Am Acad Dermatol. 2012;66(1):167–8.PubMed Anolik RB, Schaffer A, Kim EJ, Rosenbach M. Thyroid dysfunction and cutaneous sarcoidosis. J Am Acad Dermatol. 2012;66(1):167–8.PubMed
102.
go back to reference Sage RJ, Rao DS, Burke RR, Lim HW. Preventing vitamin D toxicity in patients with sarcoidosis. J Am Acad Dermatol. 2011;64(4):795–6.PubMed Sage RJ, Rao DS, Burke RR, Lim HW. Preventing vitamin D toxicity in patients with sarcoidosis. J Am Acad Dermatol. 2011;64(4):795–6.PubMed
103.
go back to reference Gupta D, Kumar S, Aggarwal AN, Verma I, Agarwal R. Interferon gamma release assay (QuantiFERON-TB Gold In Tube) in patients of sarcoidosis from a population with high prevalence of tuberculosis infection. Sarcoidosis Vasc Diffuse Lung Dis. 2011;28(2):95–101.PubMed Gupta D, Kumar S, Aggarwal AN, Verma I, Agarwal R. Interferon gamma release assay (QuantiFERON-TB Gold In Tube) in patients of sarcoidosis from a population with high prevalence of tuberculosis infection. Sarcoidosis Vasc Diffuse Lung Dis. 2011;28(2):95–101.PubMed
104.
go back to reference Studdy PR, Bird R. Serum angiotensin converting enzyme in sarcoidosis—its value in present clinical practice. Ann Clin Biochem. 1989;26(Pt 1):13–8.PubMed Studdy PR, Bird R. Serum angiotensin converting enzyme in sarcoidosis—its value in present clinical practice. Ann Clin Biochem. 1989;26(Pt 1):13–8.PubMed
105.
go back to reference Cox CE, Donohue JF, Brown CD, Kataria YP, Judson MA. The Sarcoidosis Health Questionnaire: a new measure of health-related quality of life. Am J Respir Crit Care Med. 2003;168(3):323–9.PubMed Cox CE, Donohue JF, Brown CD, Kataria YP, Judson MA. The Sarcoidosis Health Questionnaire: a new measure of health-related quality of life. Am J Respir Crit Care Med. 2003;168(3):323–9.PubMed
106.
go back to reference Victorson DE, Choi S, Judson MA, Cella D. Development and testing of item response theory-based item banks and short forms for eye, skin and lung problems in sarcoidosis. Qual Life Res. 2014;23(4):1301–13. doi:10.1007/s11136-013-0567-6 (Epub 2013 Nov 9). Victorson DE, Choi S, Judson MA, Cella D. Development and testing of item response theory-based item banks and short forms for eye, skin and lung problems in sarcoidosis. Qual Life Res. 2014;23(4):1301–13. doi:10.​1007/​s11136-013-0567-6 (Epub 2013 Nov 9).
107.
go back to reference Rosenbach M, Yeung H, Chu EY, Kim EJ, Payne AS, Takeshita J, et al. Reliability and convergent validity of the cutaneous sarcoidosis activity and morphology instrument for assessing cutaneous sarcoidosis. JAMA Dermatol. 2013;149(5):550–6.PubMed Rosenbach M, Yeung H, Chu EY, Kim EJ, Payne AS, Takeshita J, et al. Reliability and convergent validity of the cutaneous sarcoidosis activity and morphology instrument for assessing cutaneous sarcoidosis. JAMA Dermatol. 2013;149(5):550–6.PubMed
108.
go back to reference Khatri KA, Chotzen VA, Burrall BA. Lupus pernio: successful treatment with a potent topical corticosteroid. Arch Dermatol. 1995;131(5):617–8.PubMed Khatri KA, Chotzen VA, Burrall BA. Lupus pernio: successful treatment with a potent topical corticosteroid. Arch Dermatol. 1995;131(5):617–8.PubMed
109.
go back to reference Wise RD. Clinical resolution of facial cutaneous sarcoidosis with systemic colchicine and a topical corticosteroid ointment. Compr Ther. 2008 Summer;34(2):105–10. Wise RD. Clinical resolution of facial cutaneous sarcoidosis with systemic colchicine and a topical corticosteroid ointment. Compr Ther. 2008 Summer;34(2):105–10.
110.
go back to reference Volden G. Successful treatment of chronic skin diseases with clobetasol propionate and a hydrocolloid occlusive dressing. Acta Dermato-Venereol. 1992;72(1):69–71. Volden G. Successful treatment of chronic skin diseases with clobetasol propionate and a hydrocolloid occlusive dressing. Acta Dermato-Venereol. 1992;72(1):69–71.
111.
go back to reference Bersani TA, Nichols CW. Intralesional triamcinolone for cutaneous palpebral sarcoidosis. Am J Ophthalmol. 1985;99(5):561–2.PubMed Bersani TA, Nichols CW. Intralesional triamcinolone for cutaneous palpebral sarcoidosis. Am J Ophthalmol. 1985;99(5):561–2.PubMed
112.
go back to reference Callen JP. Intralesional corticosteroids. J Am Acad Dermatol. 1981;4(2):149–51.PubMed Callen JP. Intralesional corticosteroids. J Am Acad Dermatol. 1981;4(2):149–51.PubMed
113.
go back to reference Singh SK, Singh S, Pandey SS. Cutaneous sarcoidosis without systemic involvement: response to intralesional corticosteroid. Indian J Dermatol Venereol Leprol. 1996;62(4):273–4. Singh SK, Singh S, Pandey SS. Cutaneous sarcoidosis without systemic involvement: response to intralesional corticosteroid. Indian J Dermatol Venereol Leprol. 1996;62(4):273–4.
114.
go back to reference Green CM. Topical tacrolimus for the treatment of cutaneous sarcoidosis. Clin Exp Dermatol. 2007;32(4):457–8.PubMed Green CM. Topical tacrolimus for the treatment of cutaneous sarcoidosis. Clin Exp Dermatol. 2007;32(4):457–8.PubMed
115.
go back to reference Gutzmer R, Volker B, Kapp A, Werfel T. [Successful topical treatment of cutaneous sarcoidosis with tacrolimus]. Hautarzt. 2003;54(12):1193–7. Gutzmer R, Volker B, Kapp A, Werfel T. [Successful topical treatment of cutaneous sarcoidosis with tacrolimus]. Hautarzt. 2003;54(12):1193–7.
116.
go back to reference Katoh N, Mihara H, Yasuno H. Cutaneous sarcoidosis successfully treated with topical tacrolimus. Br J Dermatol. 2002;147(1):154–6.PubMed Katoh N, Mihara H, Yasuno H. Cutaneous sarcoidosis successfully treated with topical tacrolimus. Br J Dermatol. 2002;147(1):154–6.PubMed
117.
go back to reference Vano-Galvan S, Fernandez-Guarino M, Carmona LP, Harto A, Carrillo R, Jaen P. Lichenoid type of cutaneous sarcoidosis: great response to topical tacrolimus. Eur J Dermatol. 2008;18(1):89–90. Vano-Galvan S, Fernandez-Guarino M, Carmona LP, Harto A, Carrillo R, Jaen P. Lichenoid type of cutaneous sarcoidosis: great response to topical tacrolimus. Eur J Dermatol. 2008;18(1):89–90.
118.
go back to reference Hasegawa T, Suga Y, Mizuno Y, Haruna K, Ikeda S. Photodynamic therapy using intense pulsed light for cutaneous sarcoidosis. J Dermatol. 2012;39(6):564–5.PubMed Hasegawa T, Suga Y, Mizuno Y, Haruna K, Ikeda S. Photodynamic therapy using intense pulsed light for cutaneous sarcoidosis. J Dermatol. 2012;39(6):564–5.PubMed
119.
go back to reference Penrose C, Mercer SE, Shim-Chang H. Photodynamic therapy for the treatment of cutaneous sarcoidosis. J Am Acad Dermatol. 2011;65(1):e12–4.PubMed Penrose C, Mercer SE, Shim-Chang H. Photodynamic therapy for the treatment of cutaneous sarcoidosis. J Am Acad Dermatol. 2011;65(1):e12–4.PubMed
120.
go back to reference Karrer S, Abels C, Wimmershoff MB, Landthaler M, Szeimies RM. Successful treatment of cutaneous sarcoidosis using topical photodynamic therapy. Arch Dermatol. 2002;138(5):581–4.PubMed Karrer S, Abels C, Wimmershoff MB, Landthaler M, Szeimies RM. Successful treatment of cutaneous sarcoidosis using topical photodynamic therapy. Arch Dermatol. 2002;138(5):581–4.PubMed
121.
go back to reference Wilsmann-Theis D, Bieber T, Novak N. Photodynamic therapy as an alternative treatment for cutaneous sarcoidosis. Dermatology. 2008;217(4):343–6.PubMed Wilsmann-Theis D, Bieber T, Novak N. Photodynamic therapy as an alternative treatment for cutaneous sarcoidosis. Dermatology. 2008;217(4):343–6.PubMed
122.
go back to reference Kondo C, Watanabe D, Nakaseko H, Morishita M, Tsuboi T, Tamada Y, et al. Photodynamic therapy for recurrent sarcoid flexor tenosynovitis of the finger. J Am Acad Dermatol. 2006;55(5 Suppl):S99–101.PubMed Kondo C, Watanabe D, Nakaseko H, Morishita M, Tsuboi T, Tamada Y, et al. Photodynamic therapy for recurrent sarcoid flexor tenosynovitis of the finger. J Am Acad Dermatol. 2006;55(5 Suppl):S99–101.PubMed
123.
go back to reference Green JJ, Lawrence N, Heymann WR. Generalized ulcerative sarcoidosis induced by therapy with the flashlamp-pumped pulsed dye laser. Arch Dermatol. 2001;137(4):507–8.PubMed Green JJ, Lawrence N, Heymann WR. Generalized ulcerative sarcoidosis induced by therapy with the flashlamp-pumped pulsed dye laser. Arch Dermatol. 2001;137(4):507–8.PubMed
124.
go back to reference Roos S, Raulin C, Ockenfels HM, Karsai S. Successful treatment of cutaneous sarcoidosis lesions with the flashlamp pumped pulsed dye laser: a case report. Dermatol Surg. 2009;35(7):1139–40.PubMed Roos S, Raulin C, Ockenfels HM, Karsai S. Successful treatment of cutaneous sarcoidosis lesions with the flashlamp pumped pulsed dye laser: a case report. Dermatol Surg. 2009;35(7):1139–40.PubMed
125.
go back to reference Frederiksen LG, Jorgensen K. Sarcoidosis of the nose treated with laser surgery. Rhinology. 1996;34(4):245–6.PubMed Frederiksen LG, Jorgensen K. Sarcoidosis of the nose treated with laser surgery. Rhinology. 1996;34(4):245–6.PubMed
126.
go back to reference Hocar O, Faye O, Wolkenstein P, Goldzal S, Revuz J, Cosnes A. Cutaneous sarcoidosis: efficacy of KTP laser. Ann Dermatol Venereol. 2007;134(2):174–5.PubMed Hocar O, Faye O, Wolkenstein P, Goldzal S, Revuz J, Cosnes A. Cutaneous sarcoidosis: efficacy of KTP laser. Ann Dermatol Venereol. 2007;134(2):174–5.PubMed
127.
go back to reference James JC, Simpson CB. Treatment of laryngeal sarcoidosis with CO2 laser and mitomycin-C. Otolaryngol Head Neck Surg. 2004;130(2):262–4.PubMed James JC, Simpson CB. Treatment of laryngeal sarcoidosis with CO2 laser and mitomycin-C. Otolaryngol Head Neck Surg. 2004;130(2):262–4.PubMed
128.
go back to reference Ruff T, Bellens EE. Sarcoidosis of the larynx treated with CO2 laser. J Otolaryngol. 1985;14(4):245–7.PubMed Ruff T, Bellens EE. Sarcoidosis of the larynx treated with CO2 laser. J Otolaryngol. 1985;14(4):245–7.PubMed
129.
go back to reference Gleeson CM, Morar N, Staveley I, Bunker CB. Treatment of cutaneous sarcoid with topical gel psoralen and ultraviolet A. Br J Dermatol. 2011;164(4):892–4.PubMed Gleeson CM, Morar N, Staveley I, Bunker CB. Treatment of cutaneous sarcoid with topical gel psoralen and ultraviolet A. Br J Dermatol. 2011;164(4):892–4.PubMed
130.
go back to reference Graefe T, Konrad H, Barta U, Wollina U, Elsner P. Successful ultraviolet al treatment of cutaneous sarcoidosis. Br J Dermatol. 2001;145(2):354–5.PubMed Graefe T, Konrad H, Barta U, Wollina U, Elsner P. Successful ultraviolet al treatment of cutaneous sarcoidosis. Br J Dermatol. 2001;145(2):354–5.PubMed
131.
go back to reference Mahnke N, Medve-Koenigs K, Berneburg M, Ruzicka T, Neumann NJ. Cutaneous sarcoidosis treated with medium-dose UVA1. J Am Acad Dermatol. 2004;50(6):978–9.PubMed Mahnke N, Medve-Koenigs K, Berneburg M, Ruzicka T, Neumann NJ. Cutaneous sarcoidosis treated with medium-dose UVA1. J Am Acad Dermatol. 2004;50(6):978–9.PubMed
132.
go back to reference Jones E, Callen JP. Hydroxychloroquine is effective therapy for control of cutaneous sarcoidal granulomas. J Am Acad Dermatol. 1990;23(3 Pt 1):487–9.PubMed Jones E, Callen JP. Hydroxychloroquine is effective therapy for control of cutaneous sarcoidal granulomas. J Am Acad Dermatol. 1990;23(3 Pt 1):487–9.PubMed
133.
go back to reference Marchetti M, Baker MG, Noland MM. Treatment of subcutaneous sarcoidosis with hydroxychloroquine: report of 2 cases. Dermatol Online J. 2014;20(1):21250.PubMed Marchetti M, Baker MG, Noland MM. Treatment of subcutaneous sarcoidosis with hydroxychloroquine: report of 2 cases. Dermatol Online J. 2014;20(1):21250.PubMed
134.
go back to reference Meyersburg D, Schon MP, Bertsch HP, Seitz CS. Uncommon cutaneous ulcerative and systemic sarcoidosis. Successful treatment with hydroxychloroquine and compression therapy. Hautarzt. 2011;62(9):691–5.PubMed Meyersburg D, Schon MP, Bertsch HP, Seitz CS. Uncommon cutaneous ulcerative and systemic sarcoidosis. Successful treatment with hydroxychloroquine and compression therapy. Hautarzt. 2011;62(9):691–5.PubMed
135.
go back to reference Modi S, Rosen T. Micropapular cutaneous sarcoidosis: case series successfully managed with hydroxychloroquine sulfate. Cutis Cutan Med Pract. 2008;81(4):351–4. Modi S, Rosen T. Micropapular cutaneous sarcoidosis: case series successfully managed with hydroxychloroquine sulfate. Cutis Cutan Med Pract. 2008;81(4):351–4.
136.
go back to reference Siltzbach LE, Teirstein AS. Chloroquine therapy in 43 patients with intrathoracic and cutaneous sarcoidosis. Acta Med Scand Suppl. 1964;425:302–8.PubMed Siltzbach LE, Teirstein AS. Chloroquine therapy in 43 patients with intrathoracic and cutaneous sarcoidosis. Acta Med Scand Suppl. 1964;425:302–8.PubMed
137.
go back to reference Zic JA, Horowitz DH, Arzubiaga C, King LE Jr. Treatment of cutaneous sarcoidosis with chloroquine. Review of the literature. Arch Dermatol. 1991;127(7):1034–40.PubMed Zic JA, Horowitz DH, Arzubiaga C, King LE Jr. Treatment of cutaneous sarcoidosis with chloroquine. Review of the literature. Arch Dermatol. 1991;127(7):1034–40.PubMed
138.
go back to reference Badgwell C, Rosen T. Cutaneous sarcoidosis therapy updated. J Am Acad Dermatol. 2007;56(1):69–83.PubMed Badgwell C, Rosen T. Cutaneous sarcoidosis therapy updated. J Am Acad Dermatol. 2007;56(1):69–83.PubMed
139.
go back to reference Bachelez H, Senet P, Cadranel J, Kaoukhov A, Dubertret L. The use of tetracyclines for the treatment of sarcoidosis. Arch Dermatol. 2001;137(1):69–73.PubMed Bachelez H, Senet P, Cadranel J, Kaoukhov A, Dubertret L. The use of tetracyclines for the treatment of sarcoidosis. Arch Dermatol. 2001;137(1):69–73.PubMed
140.
go back to reference Miyazaki E, Ando M, Fukami T, Nureki S, Eishi Y, Kumamoto T. Minocycline for the treatment of sarcoidosis: is the mechanism of action immunomodulating or antimicrobial effect? Clin Rheumatol. 2008;27(9):1195–7.PubMed Miyazaki E, Ando M, Fukami T, Nureki S, Eishi Y, Kumamoto T. Minocycline for the treatment of sarcoidosis: is the mechanism of action immunomodulating or antimicrobial effect? Clin Rheumatol. 2008;27(9):1195–7.PubMed
141.
go back to reference Schmitt CE, Fabi SG, Kukreja T, Feinberg JS. Hypopigmented cutaneous sarcoidosis responsive to minocycline. J Drugs Dermatol. 2012;11(3):385–9.PubMed Schmitt CE, Fabi SG, Kukreja T, Feinberg JS. Hypopigmented cutaneous sarcoidosis responsive to minocycline. J Drugs Dermatol. 2012;11(3):385–9.PubMed
142.
go back to reference Steen T, English JC. Oral minocycline in treatment of cutaneous sarcoidosis. JAMA Dermatol. 2013;149(6):758–60.PubMed Steen T, English JC. Oral minocycline in treatment of cutaneous sarcoidosis. JAMA Dermatol. 2013;149(6):758–60.PubMed
143.
go back to reference Kircik LH. Doxycycline and minocycline for the management of acne: a review of efficacy and safety with emphasis on clinical implications. J Drugs Dermatol. 2010;9(11):1407–11.PubMed Kircik LH. Doxycycline and minocycline for the management of acne: a review of efficacy and safety with emphasis on clinical implications. J Drugs Dermatol. 2010;9(11):1407–11.PubMed
144.
go back to reference Park MK, Fontana JR, Babaali H, Gilbert-McClain LI, Stylianou M, Joo J, et al. Steroid-sparing effects of pentoxifylline in pulmonary sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2009;26(2):121–31. Park MK, Fontana JR, Babaali H, Gilbert-McClain LI, Stylianou M, Joo J, et al. Steroid-sparing effects of pentoxifylline in pulmonary sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2009;26(2):121–31.
145.
go back to reference Zabel P, Entzian P, Dalhoff K, Schlaak M. Pentoxifylline in treatment of sarcoidosis. Am J Respir Crit Care Med. 1997;155(5):1665–9.PubMed Zabel P, Entzian P, Dalhoff K, Schlaak M. Pentoxifylline in treatment of sarcoidosis. Am J Respir Crit Care Med. 1997;155(5):1665–9.PubMed
146.
go back to reference Baughman RP, Judson MA, Ingledue R, Craft NL, Lower EE. Efficacy and safety of apremilast in chronic cutaneous sarcoidosis. Arch Dermatol. 2012;148(2):262–4.PubMed Baughman RP, Judson MA, Ingledue R, Craft NL, Lower EE. Efficacy and safety of apremilast in chronic cutaneous sarcoidosis. Arch Dermatol. 2012;148(2):262–4.PubMed
147.
go back to reference Veien NK. Cutaneous sarcoidosis: prognosis and treatment. Clin Dermatol. 1986;4(4):75–87. Veien NK. Cutaneous sarcoidosis: prognosis and treatment. Clin Dermatol. 1986;4(4):75–87.
148.
go back to reference Baughman RP, Lower EE. Evidence-based therapy for cutaneous sarcoidosis. Clin Dermatol. 2007;25(3):334–40. Baughman RP, Lower EE. Evidence-based therapy for cutaneous sarcoidosis. Clin Dermatol. 2007;25(3):334–40.
149.
go back to reference Baughman RP, Nunes H. Therapy for sarcoidosis: evidence-based recommendations. Expert Rev Clin Immunol. 2012;8(1):95–103.PubMed Baughman RP, Nunes H. Therapy for sarcoidosis: evidence-based recommendations. Expert Rev Clin Immunol. 2012;8(1):95–103.PubMed
150.
go back to reference Doherty CB, Rosen T. Evidence-based therapy for cutaneous sarcoidosis. Drugs. 2008;68(10):1361–83.PubMed Doherty CB, Rosen T. Evidence-based therapy for cutaneous sarcoidosis. Drugs. 2008;68(10):1361–83.PubMed
151.
go back to reference Mosam A, Morar N. Recalcitrant cutaneous sarcoidosis: an evidence-based sequential approach. J Dermatol Treat. 2004;15(6):353–9. Mosam A, Morar N. Recalcitrant cutaneous sarcoidosis: an evidence-based sequential approach. J Dermatol Treat. 2004;15(6):353–9.
152.
go back to reference Veien NK, Brodthagen H. Cutaneous sarcoidosis treated with methotrexate. Br J Dermatol. 1977;97(2):213–6.PubMed Veien NK, Brodthagen H. Cutaneous sarcoidosis treated with methotrexate. Br J Dermatol. 1977;97(2):213–6.PubMed
153.
go back to reference Kouba DJ, Mimouni D, Rencic A, Nousari HC. Mycophenolate mofetil may serve as a steroid-sparing agent for sarcoidosis. Br J Dermatol. 2003;148(1):147–8.PubMed Kouba DJ, Mimouni D, Rencic A, Nousari HC. Mycophenolate mofetil may serve as a steroid-sparing agent for sarcoidosis. Br J Dermatol. 2003;148(1):147–8.PubMed
154.
go back to reference Muller-Quernheim J, Kienast K, Held M, Pfeifer S, Costabel U. Treatment of chronic sarcoidosis with an azathioprine/prednisolone regimen. Eur Respir J. 1999;14(5):1117–22.PubMed Muller-Quernheim J, Kienast K, Held M, Pfeifer S, Costabel U. Treatment of chronic sarcoidosis with an azathioprine/prednisolone regimen. Eur Respir J. 1999;14(5):1117–22.PubMed
155.
go back to reference Vorselaars AD, Wuyts WA, Vorselaars VM, Zanen P, Deneer VH, Veltkamp M, et al. Methotrexate vs azathioprine in second-line therapy of sarcoidosis. Chest. 2013;144(3):805–12.PubMed Vorselaars AD, Wuyts WA, Vorselaars VM, Zanen P, Deneer VH, Veltkamp M, et al. Methotrexate vs azathioprine in second-line therapy of sarcoidosis. Chest. 2013;144(3):805–12.PubMed
156.
go back to reference Carlesimo M, Giustini S, Rossi A, Bonaccorsi P, Calvieri S. Treatment of cutaneous and pulmonary sarcoidosis with thalidomide. J Am Acad Dermatol. 1995;32(5 Pt 2):866–9.PubMed Carlesimo M, Giustini S, Rossi A, Bonaccorsi P, Calvieri S. Treatment of cutaneous and pulmonary sarcoidosis with thalidomide. J Am Acad Dermatol. 1995;32(5 Pt 2):866–9.PubMed
157.
go back to reference Hoch O, Muller S, Buttner G, Mensing H. [Thalidomide in the treatment of cutaneous and systemic sarcoidosis]. Hautarzt. 2001;52(10 Pt 2):962–5. Hoch O, Muller S, Buttner G, Mensing H. [Thalidomide in the treatment of cutaneous and systemic sarcoidosis]. Hautarzt. 2001;52(10 Pt 2):962–5.
158.
go back to reference Lee JB, Koblenzer PS. Disfiguring cutaneous manifestation of sarcoidosis treated with thalidomide: a case report. J Am Acad Dermatol. 1998;39(5 Pt 2):835–8.PubMed Lee JB, Koblenzer PS. Disfiguring cutaneous manifestation of sarcoidosis treated with thalidomide: a case report. J Am Acad Dermatol. 1998;39(5 Pt 2):835–8.PubMed
159.
go back to reference Nguyen YT, Dupuy A, Cordoliani F, Vignon-Pennamen MD, Lebbe C, Morel P, et al. Treatment of cutaneous sarcoidosis with thalidomide. J Am Acad Dermatol. 2004;50(2):235–41.PubMed Nguyen YT, Dupuy A, Cordoliani F, Vignon-Pennamen MD, Lebbe C, Morel P, et al. Treatment of cutaneous sarcoidosis with thalidomide. J Am Acad Dermatol. 2004;50(2):235–41.PubMed
160.
go back to reference Rousseau L, Beylot-Barry M, Doutre MS, Beylot C. Cutaneous sarcoidosis successfully treated with low doses of thalidomide. Arch Dermatol. 1998;134(8):1045–6.PubMed Rousseau L, Beylot-Barry M, Doutre MS, Beylot C. Cutaneous sarcoidosis successfully treated with low doses of thalidomide. Arch Dermatol. 1998;134(8):1045–6.PubMed
161.
go back to reference Baughman RP, Lower EE. Newer therapies for cutaneous sarcoidosis: the role of thalidomide and other agents. Am J Clin Dermatol. 2004;5(6):385–94.PubMed Baughman RP, Lower EE. Newer therapies for cutaneous sarcoidosis: the role of thalidomide and other agents. Am J Clin Dermatol. 2004;5(6):385–94.PubMed
162.
go back to reference Fazzi P, Manni E, Cristofani R, Cei G, Piazza S, Calabrese R, et al. Thalidomide for improving cutaneous and pulmonary sarcoidosis in patients resistant or with contraindications to corticosteroids. Biomed Pharmacother. 2012;66(4):300–7.PubMed Fazzi P, Manni E, Cristofani R, Cei G, Piazza S, Calabrese R, et al. Thalidomide for improving cutaneous and pulmonary sarcoidosis in patients resistant or with contraindications to corticosteroids. Biomed Pharmacother. 2012;66(4):300–7.PubMed
163.
go back to reference Oliver SJ, Kikuchi T, Krueger JG, Kaplan G. Thalidomide induces granuloma differentiation in sarcoid skin lesions associated with disease improvement. Clin Immunol. 2002;102(3):225–36.PubMed Oliver SJ, Kikuchi T, Krueger JG, Kaplan G. Thalidomide induces granuloma differentiation in sarcoid skin lesions associated with disease improvement. Clin Immunol. 2002;102(3):225–36.PubMed
164.
go back to reference Dalm VA, van Hagen PM. Efficacy of lenalidomide in refractory lupus pernio. JAMA Dermatol. 2013;149(4):493–4.PubMed Dalm VA, van Hagen PM. Efficacy of lenalidomide in refractory lupus pernio. JAMA Dermatol. 2013;149(4):493–4.PubMed
165.
go back to reference Burns AM, Green PJ, Pasternak S. Etanercept-induced cutaneous and pulmonary sarcoid-like granulomas resolving with adalimumab. J Cutan Pathol. 2012;39(2):289–93.PubMed Burns AM, Green PJ, Pasternak S. Etanercept-induced cutaneous and pulmonary sarcoid-like granulomas resolving with adalimumab. J Cutan Pathol. 2012;39(2):289–93.PubMed
166.
go back to reference Field S, Regan AO, Sheahan K, Collins P. Recalcitrant cutaneous sarcoidosis responding to adalimumab but not to etanercept. Clin Exp Dermatol. 2010;35(7):795–6.PubMed Field S, Regan AO, Sheahan K, Collins P. Recalcitrant cutaneous sarcoidosis responding to adalimumab but not to etanercept. Clin Exp Dermatol. 2010;35(7):795–6.PubMed
167.
go back to reference Heffernan MP, Smith DI. Adalimumab for treatment of cutaneous sarcoidosis. Arch Dermatol. 2006;142(1):17–9.PubMed Heffernan MP, Smith DI. Adalimumab for treatment of cutaneous sarcoidosis. Arch Dermatol. 2006;142(1):17–9.PubMed
168.
go back to reference Pariser RJ, Paul J, Hirano S, Torosky C, Smith M. A double-blind, randomized, placebo-controlled trial of adalimumab in the treatment of cutaneous sarcoidosis. J Am Acad Dermatol. 2013;68(5):765–73.PubMed Pariser RJ, Paul J, Hirano S, Torosky C, Smith M. A double-blind, randomized, placebo-controlled trial of adalimumab in the treatment of cutaneous sarcoidosis. J Am Acad Dermatol. 2013;68(5):765–73.PubMed
169.
go back to reference Philips MA, Lynch J, Azmi FH. Ulcerative cutaneous sarcoidosis responding to adalimumab. J Am Acad Dermatol. 2005;53(5):917.PubMed Philips MA, Lynch J, Azmi FH. Ulcerative cutaneous sarcoidosis responding to adalimumab. J Am Acad Dermatol. 2005;53(5):917.PubMed
170.
go back to reference Fok KC, Ng WW, Henderson CJ, Connor SJ. Cutaneous sarcoidosis in a patient with ulcerative colitis on infliximab. J Crohns Colitis. 2012;6(6):708–12.PubMed Fok KC, Ng WW, Henderson CJ, Connor SJ. Cutaneous sarcoidosis in a patient with ulcerative colitis on infliximab. J Crohns Colitis. 2012;6(6):708–12.PubMed
171.
go back to reference Heffernan MP, Anadkat MJ. Recalcitrant cutaneous sarcoidosis responding to infliximab. Arch Dermatol. 2005;141(7):910–1.PubMed Heffernan MP, Anadkat MJ. Recalcitrant cutaneous sarcoidosis responding to infliximab. Arch Dermatol. 2005;141(7):910–1.PubMed
172.
go back to reference Meyerle JH, Shorr A. The use of infliximab in cutaneous sarcoidosis. J Drugs Dermatol. 2003;2(4):413–4.PubMed Meyerle JH, Shorr A. The use of infliximab in cutaneous sarcoidosis. J Drugs Dermatol. 2003;2(4):413–4.PubMed
173.
go back to reference Rosen T, Doherty C. Successful long-term management of refractory cutaneous and upper airway sarcoidosis with periodic infliximab infusion. Dermatol Online J. 2007;13(3):14.PubMed Rosen T, Doherty C. Successful long-term management of refractory cutaneous and upper airway sarcoidosis with periodic infliximab infusion. Dermatol Online J. 2007;13(3):14.PubMed
174.
go back to reference Sene T, Juillard C, Rybojad M, Cordoliani F, Lebbe C, Morel P, et al. Infliximab as a steroid-sparing agent in refractory cutaneous sarcoidosis: single-center retrospective study of 9 patients. J Am Acad Dermatol. 2012;66(2):328–32.PubMed Sene T, Juillard C, Rybojad M, Cordoliani F, Lebbe C, Morel P, et al. Infliximab as a steroid-sparing agent in refractory cutaneous sarcoidosis: single-center retrospective study of 9 patients. J Am Acad Dermatol. 2012;66(2):328–32.PubMed
175.
go back to reference Tu J, Chan J. Cutaneous sarcoidosis and infliximab: evidence for efficacy in refractory disease. Aust J Dermatol. 2013. doi:10.1111/ajd.12056 (Epub ahead of print). Tu J, Chan J. Cutaneous sarcoidosis and infliximab: evidence for efficacy in refractory disease. Aust J Dermatol. 2013. doi:10.​1111/​ajd.​12056 (Epub ahead of print).
176.
go back to reference Tuchinda P, Bremmer M, Gaspari AA. A case series of refractory cutaneous sarcoidosis successfully treated with infliximab. Dermatol Ther. 2012;2(1):11. Tuchinda P, Bremmer M, Gaspari AA. A case series of refractory cutaneous sarcoidosis successfully treated with infliximab. Dermatol Ther. 2012;2(1):11.
177.
go back to reference Wanat KA, Rosenbach M. Case series demonstrating improvement in chronic cutaneous sarcoidosis following treatment with TNF inhibitors. Arch Dermatol. 2012;148(9):1097–100.PubMed Wanat KA, Rosenbach M. Case series demonstrating improvement in chronic cutaneous sarcoidosis following treatment with TNF inhibitors. Arch Dermatol. 2012;148(9):1097–100.PubMed
178.
go back to reference Utz JP, Limper AH, Kalra S, Specks U, Scott JP, Vuk-Pavlovic Z, et al. Etanercept for the treatment of stage II and III progressive pulmonary sarcoidosis. Chest. 2003;124(1):177–85.PubMed Utz JP, Limper AH, Kalra S, Specks U, Scott JP, Vuk-Pavlovic Z, et al. Etanercept for the treatment of stage II and III progressive pulmonary sarcoidosis. Chest. 2003;124(1):177–85.PubMed
179.
go back to reference Stagaki E, Mountford WK, Lackland DT, Judson MA. The treatment of lupus pernio: results of 116 treatment courses in 54 patients. Chest. 2009;135(2):468–76.PubMed Stagaki E, Mountford WK, Lackland DT, Judson MA. The treatment of lupus pernio: results of 116 treatment courses in 54 patients. Chest. 2009;135(2):468–76.PubMed
180.
go back to reference Thielen AM, Barde C, Saurat JH, Laffitte E. Refractory chronic cutaneous sarcoidosis responsive to dose escalation of TNF-alpha antagonists. Dermatology. 2009;219(1):59–62.PubMed Thielen AM, Barde C, Saurat JH, Laffitte E. Refractory chronic cutaneous sarcoidosis responsive to dose escalation of TNF-alpha antagonists. Dermatology. 2009;219(1):59–62.PubMed
181.
go back to reference Fraser SJ, Hill AT, McKay DA, Reid WA, Mathers ME, MacDougall G, et al. Cutaneous tuberculosis revealed by infliximab therapy for presumed sarcoidosis. Clin Exp Dermatol. 2010;35(4):e141–2.PubMed Fraser SJ, Hill AT, McKay DA, Reid WA, Mathers ME, MacDougall G, et al. Cutaneous tuberculosis revealed by infliximab therapy for presumed sarcoidosis. Clin Exp Dermatol. 2010;35(4):e141–2.PubMed
182.
go back to reference Dhaille F, Viseux V, Caudron A, Dadban A, Tribout C, Boumier P, et al. Cutaneous sarcoidosis occurring during anti-TNF-alpha treatment: report of two cases. Dermatology. 2010;220(3):234–7.PubMed Dhaille F, Viseux V, Caudron A, Dadban A, Tribout C, Boumier P, et al. Cutaneous sarcoidosis occurring during anti-TNF-alpha treatment: report of two cases. Dermatology. 2010;220(3):234–7.PubMed
183.
go back to reference Santos G, Sousa LE, Joao AM. Exacerbation of recalcitrant cutaneous sarcoidosis with adalimumab—a paradoxical effect? A case report. An Bras Dermatol. 2013;88(6 Suppl 1):26–8. Santos G, Sousa LE, Joao AM. Exacerbation of recalcitrant cutaneous sarcoidosis with adalimumab—a paradoxical effect? A case report. An Bras Dermatol. 2013;88(6 Suppl 1):26–8.
184.
go back to reference Georgiou S, Monastirli A, Pasmatzi E, Tsambaos D. Cutaneous sarcoidosis: complete remission after oral isotretinoin therapy. Acta Dermato-Venereol. 1998;78(6):457–9. Georgiou S, Monastirli A, Pasmatzi E, Tsambaos D. Cutaneous sarcoidosis: complete remission after oral isotretinoin therapy. Acta Dermato-Venereol. 1998;78(6):457–9.
185.
go back to reference Pignone AM, Rosso AD, Fiori G, Matucci-Cerinic M, Becucci A, Tempestini A, et al. Melatonin is a safe and effective treatment for chronic pulmonary and extrapulmonary sarcoidosis. J Pineal Res. 2006;41(2):95–100.PubMed Pignone AM, Rosso AD, Fiori G, Matucci-Cerinic M, Becucci A, Tempestini A, et al. Melatonin is a safe and effective treatment for chronic pulmonary and extrapulmonary sarcoidosis. J Pineal Res. 2006;41(2):95–100.PubMed
186.
go back to reference York EL, Kovithavongs T, Man SF, Rebuck AS, Sproule BJ. Cyclosporine and chronic sarcoidosis. Chest. 1990;98(4):1026–9.PubMed York EL, Kovithavongs T, Man SF, Rebuck AS, Sproule BJ. Cyclosporine and chronic sarcoidosis. Chest. 1990;98(4):1026–9.PubMed
187.
go back to reference Sahoo DH, Bandyopadhyay D, Xu M, Pearson K, Parambil JG, Lazar CA, et al. Effectiveness and safety of leflunomide for pulmonary and extrapulmonary sarcoidosis. Eur Respir J. 2011;38(5):1145–50.PubMed Sahoo DH, Bandyopadhyay D, Xu M, Pearson K, Parambil JG, Lazar CA, et al. Effectiveness and safety of leflunomide for pulmonary and extrapulmonary sarcoidosis. Eur Respir J. 2011;38(5):1145–50.PubMed
Metadata
Title
A Practical Approach to Cutaneous Sarcoidosis
Authors
Karolyn A. Wanat
Misha Rosenbach
Publication date
01-08-2014
Publisher
Springer International Publishing
Published in
American Journal of Clinical Dermatology / Issue 4/2014
Print ISSN: 1175-0561
Electronic ISSN: 1179-1888
DOI
https://doi.org/10.1007/s40257-014-0079-3

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