Published in:
01-08-2020 | Deep Brain Stimulation | Letter to the Editor
A case of refractory hypernatremia in the setting of parkinsonism–hyperpyrexia syndrome
Authors:
Ho-Sung Ryu, Seok-Yeol Yang
Published in:
Acta Neurologica Belgica
|
Issue 4/2020
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Excerpt
Parkinsonism–hyperpyrexia syndrome (PHS) is a rare, but life-threatening condition in patients with Parkinson’s disease (PD). The clinical features of PHS include muscle rigidity, hyperthermia, altered mental status, and autonomic instability. Laboratory findings in these patients may indicate an increased creatine kinase, leukocytosis, deranged liver function tests, and metabolic acidosis [
1]. Primarily, rapid recognition of PHS is critical to appropriately treat these patients. Herein, we report a patient with PD dementia who developed hypernatremia in the setting of PHS. This was successfully resolved by administering levodopa therapy. …