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01-03-2018 | Original Article

Meningoencephaloradiculitis following infection with tick borne encephalitis virus: case report and review of the literature

Authors: Stephanie Du Four, Rembert Mertens, Wietse Wiels, Jacques De Keyser, Veronique Bissay, Anja Flamez

Published in: Acta Neurologica Belgica | Issue 1/2018

Abstract

Tick borne encephalitis (TBE) is an infectious zoonotic disease caused by an RNA virus that is endemic to Central and Eastern Europe, Russia, and large parts of Asia. The tick borne encephalitis virus (TBEV) is transmitted through the saliva of infected ticks and infected goat milk. In the vast majority of cases, an infection with TBEV has a subclinical course. However, in some cases, it leads to neurological symptoms due to meningitis, meningoencephalitis, meningoencephalomyelitis, or meningoencephaloradiculitis. Here, we present the first case of meningoencephaloradiculitis in Belgium.

Bogovic P, Lotric-furlan S, Strle F (2010) What tick-borne encephalitis may look like: clinical signs and symptoms. Travel Med Infect Dis 8:246–250CrossRefPubMed

Bogovic P, Strle F (2015) Tick-borne encephalitis: a review of epidemiology, clinical characteristics, and management. World J Clin Cases 3:430–442CrossRefPubMedPubMedCentral

Marsala SZ, Pistacchi M, Gioulis M, Mel R, Marchini C, Francavilla E (2014) Neurological complications of tick borne encephalitis: the experience of 89 patients studied and literature review. Neurol Sci 35:15–21CrossRef

Kaiser R (2012) Tick-borne encephalitis: clinical findings and prognosis in adults. Wien Med Wochschr 162:239–243CrossRef

Kaiser R (1995) Tick-borne encephalitis in southern Germany. Lancet 345:463CrossRefPubMed

Kaiser R (1999) The clinical and epidemiological pro le of tick-borne encephalitis in southern Germany 1994–98. Brain 122:2067–2078CrossRefPubMed

Marjelund S, Jaaskelainen A, Tikkakoski T, Tuisku S, Vapalahti O (2006) Gadolinium enhancement of cauda equina: a new MR imaging finding in the radiculitic form of tick-borne encephalitis. Am J Neuroradiol 27:995–997PubMed

Ponfick M, Hacker S, Gdynia H, Linden R, Gränz M, Nowak D (2012) Meningoencephaloradiculomyelitis after tick-borne encephalitis virus infection: a case series. Eur J Neurol 19:776–782CrossRefPubMed

Kaiser R, Vollmer H, Schmidtke K, Rauer S, Berger W (1997) Gores D [Follow-up and prognosis of early summer meningoencephalitis]. Nervenarzt 68:324–330CrossRefPubMed

10.

Aendekerk RPP, Schrivers ANA, Koehler PJ (1996) Tick-borne encephalitis complicated by a polio-like syndrome following a holiday in central Europe. Clin Neurol Neurosurg 98:262–264CrossRefPubMed

11.

Marsala SZ, Francavilla E, Gioulis M, Candeago RM, Mondardini V, Gentile M, Ferracci F, Guzzo F, Granata C, Marchini C (2012) Isolated polio-like syndrome after tick-borne encephalitis presenting with acute hyperckemia. Neurol Sci 33:669–672CrossRef

12.

Ponfick M, Hacker S, Gdynia HJ, Linden R, Gränz M, Nowak DA (2012) Meningoencephaloradiculomyelitis after tick-borne encephalitis virus infection: a case series. Eur J Neurol 19:776–782CrossRefPubMed

13.

Saksida A, Duh D, Lotric-furlan S, Strle F, Petrovec M, Avsic-Zupanc T (2005) The importance of tick-borne encephalitis virus RNA detection for early differential diagnosis of tick-borne encephalitis. J Clin Virol 33:331–335CrossRefPubMed

14.

Holzmann H (2003) Diagnosis of tick-borne encephalitis. Vaccine 21:36–40CrossRef

15.

Stiasny K, Aberle JH, Chmelik V, Karrer U, Holzmann H, Heinz FX (2012) Quantitative determination of IgM antibodies reduces the pitfalls in the serodiagnosis of tick-borne encephalitis. J Clin Virol 54:115–120CrossRefPubMed

16.

Palus M, Bily T, Elsterova J, Langhansova H, Salat J, Vancova M, Ruzek D (2014) Infection and injury of human astrocytes by tick-borne encephalitis virus. J Gen Virol 95:2411–2426CrossRefPubMed

17.

Růžek D, Dobler G, Mantke OD (2010) Tick-borne encephalitis: pathogenesis and clinical implications. Travel Med Infect Dis 8:223–232CrossRefPubMed

18.

Haglund M, Günther G (2003) Tick-borne encephalitis-pathogenesis, clinical course and long-term follow-up. Vaccine 21:S1/11–S1/18

19.

Alkadhi H, Kollias SS (2000) MRI in tick-borne encephalitis. Neuroradiology 42:753–755CrossRefPubMed

20.

21.

Bender A, Walther EU, Pfister H (2005) Severe tick borne encephalitis with simultaneous brain stem, bithalamic, and spinal cord involvement documented by MRI. J Neurol Neurosurg Psychiatry 76:135–137CrossRefPubMedPubMedCentral

22.

Pichler A, Sellner J, Harutyunyan G, Sonnleitner A, Klobassa DS, Archelos-garcia J, Rock H, Gattringer T, Fazekas F (2017) Magnetic resonance imaging and clinical findings in adults with tick-borne encephalitis. J Neurol Sci 375:266–269CrossRefPubMed

Title: Meningoencephaloradiculitis following infection with tick borne encephalitis virus: case report and review of the literature
Authors: Stephanie Du Four
Rembert Mertens
Wietse Wiels
Jacques De Keyser
Veronique Bissay
Anja Flamez
Publication date: 01-03-2018
Publisher: Springer International Publishing
Published in: Acta Neurologica Belgica / Issue 1/2018
Print ISSN: 0300-9009
Electronic ISSN: 2240-2993
DOI: https://doi.org/10.1007/s13760-017-0873-9

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Meningoencephaloradiculitis following infection with tick borne encephalitis virus: case report and review of the literature

Abstract

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