Characteristic callosal involvement in Susac’s syndrome

Excerpt

After experiencing paresthesia in the right hand and increasing headache, instability and black spots in the left visual field since 2 weeks, a 30-year-old female presented with an episode of irresponsiveness with prolonged confusion. There was some spontaneous improvement of the cognitive impairment but short-term memory difficulties remained. We found a decreased vision of the right eye (best corrected ETDRS visual acuity 20/32 compared 20/40 on the left), an instable gait, and a right-sided hyperreflexia. Subsequently, she developed auditory loss and tinnitus. She became increasingly apathetic and somnolent, culminating in another episode of loss of consciousness, now with myoclonic jerking of the right half of the face. …