Skip to main content
Top
Published in: International Cancer Conference Journal 1/2019

01-01-2019 | Case report

Epithelioid hemangioendothelioma of the parotid gland: a case report

Authors: Yusuke Koide, Eiichi Sasaki, Katsuhiro Masago, Shiro Fujita, Shintaro Beppu, Daisuke Nishikawa, Hidenori Suzuki, Yasuhisa Hasegawa, Yasushi Yatabe, Nobuhiro Hanai

Published in: International Cancer Conference Journal | Issue 1/2019

Login to get access

Abstract

We present the case of a patient with epithelioid hemangioendothelioma of the parotid gland. A 70-year-old female developed swelling and pain in the lower part of the left ear 18 months previously and had visited a local hospital. Fine-needle aspiration cytology revealed no definitive diagnosis, but incisional biopsy under local anesthesia suggested epithelioid hemangioendothelioma. She was then transferred to our hospital, where she underwent total extirpation of the left parotid gland, left cervical lymph node dissection, and postoperative radiation therapy. However, she died from distant metastases 13 months after surgery. No previous study has reported any case of distant metastasis or death due to epithelioid hemangioendothelioma of the parotid gland. To the best of our knowledge, this is the first case report on distant metastasis and death due to the development of parotid gland cancer.
Literature
1.
go back to reference Weiss SW, Enzinger FM (1982) Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma. Cancer 50(5):970–981CrossRefPubMed Weiss SW, Enzinger FM (1982) Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma. Cancer 50(5):970–981CrossRefPubMed
2.
go back to reference Bollinger BK, Laskin WB, Knight CB (1994) Epithelioid hemangioendothelioma with multiple site involvement. Literature review observations. Cancer 73(3):610–615CrossRefPubMed Bollinger BK, Laskin WB, Knight CB (1994) Epithelioid hemangioendothelioma with multiple site involvement. Literature review observations. Cancer 73(3):610–615CrossRefPubMed
3.
go back to reference Fletcher CDM, International Academy of P (2013) WHO classification of tumours of soft tissue and bone. World Health Organization classification of tumours, 4th edn. IARC Press, Lyon Fletcher CDM, International Academy of P (2013) WHO classification of tumours of soft tissue and bone. World Health Organization classification of tumours, 4th edn. IARC Press, Lyon
4.
go back to reference Matsuzawa S, Kanazawa T, Yamaguchi T, Nishino H, Kawada K, Ichimura K (2013) Case of high-risk epithelioid hemangioendothelioma of the neck. Head Neck 35(10):317–320 Matsuzawa S, Kanazawa T, Yamaguchi T, Nishino H, Kawada K, Ichimura K (2013) Case of high-risk epithelioid hemangioendothelioma of the neck. Head Neck 35(10):317–320
6.
go back to reference Franccedil MM, Souza GL, Frank M, Fabris VE, Tagliarini JV, Mazeto G (2011) Malignant epithelioid hemangioendothelioma of the thyroid: a case report. Med Case Stud 2(4):29–31 Franccedil MM, Souza GL, Frank M, Fabris VE, Tagliarini JV, Mazeto G (2011) Malignant epithelioid hemangioendothelioma of the thyroid: a case report. Med Case Stud 2(4):29–31
7.
go back to reference Mentzel T, Beham A, Calonje E, Katenkamp D, Fletcher CD (1997) Epithelioid hemangioendothelioma of skin and soft tissues: clinicopathologic and immunohistochemical study of 30 cases. Am J Surg Pathol 21(4):363–374CrossRefPubMed Mentzel T, Beham A, Calonje E, Katenkamp D, Fletcher CD (1997) Epithelioid hemangioendothelioma of skin and soft tissues: clinicopathologic and immunohistochemical study of 30 cases. Am J Surg Pathol 21(4):363–374CrossRefPubMed
8.
go back to reference Errani C, Zhang L, Sung YS, Hajdu M, Singer S, Maki RG, Healey JH, Antonescu CR (2011) A novel WWTR1–CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different anatomic sites. Genes Chromosom Cancer 50(8):644–653CrossRefPubMed Errani C, Zhang L, Sung YS, Hajdu M, Singer S, Maki RG, Healey JH, Antonescu CR (2011) A novel WWTR1–CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different anatomic sites. Genes Chromosom Cancer 50(8):644–653CrossRefPubMed
9.
go back to reference Pigadas N, Mohamid W, McDermott P (2000) Epithelioid hemangioendothelioma of the parotid salivary gland. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol 89(6):730–738CrossRef Pigadas N, Mohamid W, McDermott P (2000) Epithelioid hemangioendothelioma of the parotid salivary gland. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol 89(6):730–738CrossRef
10.
go back to reference Amin K (2003) Epithelioid hemangioendothelioma of the parotid gland with atypical features. Otolaryngol Head Neck Surg 129(5):596–598CrossRefPubMed Amin K (2003) Epithelioid hemangioendothelioma of the parotid gland with atypical features. Otolaryngol Head Neck Surg 129(5):596–598CrossRefPubMed
11.
go back to reference Falvo L, Marzullo A, Catania A, Sorrenti S, Berni A, Bonifazi AP, De Stefano M, De Antoni E (2004) Epithelioid haemangioendothelioma of the parotid salivary gland: a case report. Chir Ital 56(3):457–462PubMed Falvo L, Marzullo A, Catania A, Sorrenti S, Berni A, Bonifazi AP, De Stefano M, De Antoni E (2004) Epithelioid haemangioendothelioma of the parotid salivary gland: a case report. Chir Ital 56(3):457–462PubMed
12.
go back to reference Deyrup AT, Tighiouart M, Montag AG, Weiss SW (2008) Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases. Am J Surg Pathol 32(6):924–927CrossRefPubMed Deyrup AT, Tighiouart M, Montag AG, Weiss SW (2008) Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases. Am J Surg Pathol 32(6):924–927CrossRefPubMed
13.
go back to reference Sardaro A, Bardoscia L, Petruzzelli MF, Portaluri M (2014) Epithelioid hemangioendothelioma: an overview and update on a rare vascular tumor. Oncol Rev 8(2):259CrossRefPubMedPubMedCentral Sardaro A, Bardoscia L, Petruzzelli MF, Portaluri M (2014) Epithelioid hemangioendothelioma: an overview and update on a rare vascular tumor. Oncol Rev 8(2):259CrossRefPubMedPubMedCentral
Metadata
Title
Epithelioid hemangioendothelioma of the parotid gland: a case report
Authors
Yusuke Koide
Eiichi Sasaki
Katsuhiro Masago
Shiro Fujita
Shintaro Beppu
Daisuke Nishikawa
Hidenori Suzuki
Yasuhisa Hasegawa
Yasushi Yatabe
Nobuhiro Hanai
Publication date
01-01-2019
Publisher
Springer Japan
Published in
International Cancer Conference Journal / Issue 1/2019
Electronic ISSN: 2192-3183
DOI
https://doi.org/10.1007/s13691-018-0351-0

Other articles of this Issue 1/2019

International Cancer Conference Journal 1/2019 Go to the issue
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine