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International Cancer Conference Journal
Published in: International Cancer Conference Journal 4/2017

01-10-2017 | Case report

Complete resection of a huge pancreatic undifferentiated carcinoma with osteoclast-like giant cells

Authors: Tomohiro Yazawa, Akira Watanabe, Kenichiro Araki, Atsuki Segawa, Keitaro Hirai, Norio Kubo, Takamichi Igarashi, Mariko Tsukagoshi, Norihiro Ishii, Kouki Hoshino, Hiroyuki Kuwano, Ken Shirabe

Published in: International Cancer Conference Journal | Issue 4/2017

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Abstract

Pancreatic undifferentiated carcinoma with osteoclast-like giant cells (PUC-OGC) is a rare neoplasm. We report a case of rapidly advancing PUC-OGC. A 54-year-old man had elevated tumor marker levels. Abdominal computed tomography showed a cystic mass in the body and tail of the pancreas, which infiltrated adjacent organs. The tumor exhibited rapid growth (doubling time: 39 days) but no metastases. We diagnosed PUC-OGC clinically and excised the pancreatic body and tail along with the spleen, left kidney, adrenal gland, and transverse colon. Pathological diagnosis showed histology consistent with PUC-OGC and a negative margin without nodal involvement despite the tumor being 28 cm in maximum diameter and having invaded the left kidney. The patient survived a year with a recurrence of liver metastasis after the initial surgery due to the partial hepatectomy and chemotherapy. Complete resection might be a good strategy to cure PUC-OGC in this case.
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Metadata
Title
Complete resection of a huge pancreatic undifferentiated carcinoma with osteoclast-like giant cells
Authors
Tomohiro Yazawa
Akira Watanabe
Kenichiro Araki
Atsuki Segawa
Keitaro Hirai
Norio Kubo
Takamichi Igarashi
Mariko Tsukagoshi
Norihiro Ishii
Kouki Hoshino
Hiroyuki Kuwano
Ken Shirabe
Publication date
01-10-2017
Publisher
Springer Japan
Published in
International Cancer Conference Journal / Issue 4/2017
Electronic ISSN: 2192-3183
DOI
https://doi.org/10.1007/s13691-017-0305-y

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