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Published in: Current Dermatology Reports 1/2018

01-03-2018 | Psoriasis (Jaishin Wu, Section Editor)

Review Update on Topical Therapy for Psoriasis

Authors: Vermén M. Verallo-Rowell, Stephanie S. Katalbas, Mara Therese P. Evangelista, Johannes F. Dayrit

Published in: Current Dermatology Reports | Issue 1/2018

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Abstract

Purpose of Review

Studies show frequent usage but low adherence rates and poor satisfaction from topical therapy for psoriasis. These were attributed to low efficacy, inconvenience of application, and poor cosmetic quality for different body parts.

Recent Findings

Multicenter surveys on patients suggest a two-way holistic approach, where patients convey what bothers them most and doctors explain how products address specific concerns. New rapid response targeted topical agents, in cosmetically acceptable preparations, applied less often, are undergoing efficacy and safety studies, ideally on large populations up to 1 year or more. Until available, this review addresses gaps in knowledge on how to maximize effects of emollients, used alone, with physiologic lipids, or as base for active topical therapy.

Summary

Updates—on how psoriasis skin becomes itchy, red, dry, thick, and scaly from inflammation and barrier defects—explain clinical responses to the physical, chemical, and functional properties of psoriasis topical therapies.
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Metadata
Title
Review Update on Topical Therapy for Psoriasis
Authors
Vermén M. Verallo-Rowell
Stephanie S. Katalbas
Mara Therese P. Evangelista
Johannes F. Dayrit
Publication date
01-03-2018
Publisher
Springer US
Published in
Current Dermatology Reports / Issue 1/2018
Electronic ISSN: 2162-4933
DOI
https://doi.org/10.1007/s13671-018-0209-x

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