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Current Dermatology Reports

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01-09-2017 | Epidemiology (R Dellavalle, Section Editor)

Environmental Risk Factors for Development of Atopic Dermatitis: a Systematic Review

Authors: Nazanin Kuseh Kalani Yazd, Cory A. Dunnick

Published in: Current Dermatology Reports | Issue 3/2017

Abstract

Purpose of Review

The purpose of this study was to systematically review studies conducted between April 2015 and April 2017 on the environmental risks for the development of AD. We sought to identify (1) environmental risks associated with AD, (2) the proportion of studies for each environmental risk, and (3) environmental risks that need further investigation.

Recent Findings

Recent studies have found genetic predisposition and environmental triggers are involved in the pathogenesis of AD. Genome-wide linkage and candidate gene association studies have led to the linkage of at least 11 different chromosomes and 46 genes. However, the discordance in expression of atopy among monozygotic twins suggests an environmental role.

Summary

Our systematic review found significant risk of development of AD in genetically susceptible children with environmental risk factors of maternal atopy, environmental pollutants, food allergy, and early antibiotic exposure. We suggest future research should aim to better identify environmental pollutants that may increase the development of AD in neonates and children.

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Title: Environmental Risk Factors for Development of Atopic Dermatitis: a Systematic Review
Authors: Nazanin Kuseh Kalani Yazd
Cory A. Dunnick
Publication date: 01-09-2017
Publisher: Springer US
Published in: Current Dermatology Reports / Issue 3/2017
Electronic ISSN: 2162-4933
DOI: https://doi.org/10.1007/s13671-017-0189-2

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Environmental Risk Factors for Development of Atopic Dermatitis: a Systematic Review

Abstract

Purpose of Review

Recent Findings

Summary

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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