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Current Dermatology Reports
Published in: Current Dermatology Reports 1/2012

01-03-2012 | Epidemiology (J Gelfand, Section Editor)

Comorbidity in Atopic Dermatitis

Author: Eric L. Simpson

Published in: Current Dermatology Reports | Issue 1/2012

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Abstract

The negative impact of atopic dermatitis (AD) often extends beyond the skin. Children with AD experience increased rates of infectious, mental health, and allergic diseases compared to their non-atopic peers. The mechanisms underlying these associations remain elusive. New insights from genetic and epidermal research pinpoint the skin barrier as a primary initiator of AD. Epicutaneous sensitization represents an intriguing new model that links a disrupted skin barrier to the later development of IgE-mediated diseases in patients with AD. Recent epidemiologic studies have identified new comorbidities linked to AD as well, including several mental health disorders and obesity. This article reviews the recent literature regarding both classic and newly described AD comorbidities.
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Metadata
Title
Comorbidity in Atopic Dermatitis
Author
Eric L. Simpson
Publication date
01-03-2012
Publisher
Current Science Inc.
Published in
Current Dermatology Reports / Issue 1/2012
Electronic ISSN: 2162-4933
DOI
https://doi.org/10.1007/s13671-011-0003-5

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