Top

Published in:

09-06-2022 | Dengue Virus | Case Report

Dengue fever presenting as acute cerebellar ataxia: Case report and literature review

Authors: Arthur Cesário de Holanda, Eduardo Maranhão, Luísa Van Der Linden Ferreira Silva, Marcos Eugenio Ramalho Bezerra, Eduardo Sousa de Melo

Published in: Journal of NeuroVirology | Issue 3/2022

Abstract

Dengue fever has been associated with several neurological complications, cerebellar involvement being among the rarest of them. Here, we describe the case of a 70-year-old female who presented a cerebellar syndrome during the first day of an arboviral infection, posteriorly confirmed as dengue fever. Among the seven other cases in which the relationship between dengue virus and ataxia was reported, only in one cerebellar presentation occurred as early. Onset, course, and prognosis, as well as the adequate investigation and management of these patients, are discussed. While the disease pattern is not better characterized by future studies, differential diagnosis and close follow-up are essential tools for guaranteeing good outcomes.

Desai J, Mitchell WG (2012) Acute cerebellar ataxia, acute cerebellitis, and opsoclonus-myoclonus syndrome. J Child Neurol 27(11):1482–1488CrossRef

Gulati S, Maheshwari A (2007) Atypical manifestations of dengue. Trop Med Int Health TM IH 12(9):1087–1095CrossRef

Hegde V, Aziz Z, Kumar S, Bhat M, Prasad C, Gupta AK, Netravathi M, Saini J (2015) Dengue encephalitis with predominant cerebellar involvement: report of eight cases with MR and CT imaging features. Eur Radiol 25(3):719–725CrossRef

Karunarathne S, Udayakumara Y, Fernando H (2012) Epstein-Barr virus co-infection in a patient with dengue fever presenting with post-infectious cerebellitis: a case report. J Med Case Reports 6:43CrossRef

Khoo CS (2018) Dengue cerebellitis: a case report and literature review. Am J Case Rep 19:864–867CrossRef

Li G-H, Ning Z-J, Liu Y-M, Li X-H (2017) Neurological manifestations of dengue infection. Front Cell Infect Microbiol 7:449. https://doi.org/10.3389/fcimb.2017.00449CrossRefPubMedPubMedCentral

Patel ML, Shyam R, Pushkar DK, Sachan R (2017) Dengue encephalitis with cerebellar involvement: a rare case report. Ann Trop Med Public Health 10(3):734

Weeratunga PN, Caldera HPMC, Gooneratne IK, Gamage R, Perera WSP, Ranasinghe GV, Niraj M (2014) Spontaneously resolving cerebellar syndrome as a sequelae of dengue viral infection: a case series from Sri Lanka. Pract Neurol 14(3):176–178CrossRef

WHO (2021) Dengue and severe dengue. https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue. Accessed 28 Jun 2020

Withana M, Rodrigo C, Chang T, Karunanayake P, Rajapakse S (2014) Dengue fever presenting with acute cerebellitis: a case report. BMC Res Notes 7:125CrossRef

Title: Dengue fever presenting as acute cerebellar ataxia: Case report and literature review
Authors: Arthur Cesário de Holanda
Eduardo Maranhão
Luísa Van Der Linden Ferreira Silva
Marcos Eugenio Ramalho Bezerra
Eduardo Sousa de Melo
Publication date: 09-06-2022
Publisher: Springer International Publishing
Keyword: Dengue Virus
Published in: Journal of NeuroVirology / Issue 3/2022
Print ISSN: 1355-0284
Electronic ISSN: 1538-2443
DOI: https://doi.org/10.1007/s13365-022-01082-3

At a glance: The STEP trials

Springer Medicine

Dengue fever presenting as acute cerebellar ataxia: Case report and literature review

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 3/2022

A fulminant case of Epstein-Barr Virus encephalitis with multiorgan dysfunction

T-lymphocyte activation markers in patients with HIV-1-associated neurocognitive disorder

Cognitive dysfunction following COVID-19 infection

Infection of human microglial cell line CHME-3 to study neuropathogenesis of chikungunya virus

HIV-1 subtype C Tat exon-1 amino acid residue 24K is a signature for neurocognitive impairment

Limited evidence for a moderating effect of HIV status on brain age in heavy episodic drinkers