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01-02-2020 | Vasculitis | Case Report

Disseminated cutaneous herpes zoster and multiple cerebral infarcts in an adult with diabetes mellitus

Authors: Chun-Fu Lin, Chien-Tai Hong, Wei-Hwa Lee, Dean Wu, Chaur-Jong Hu, Chen-Chih Chung

Published in: Journal of NeuroVirology | Issue 1/2020

Abstract

Ischemic stroke is a rare complication of varicella-zoster virus (VZV) infection. We present the case of a patient with a medical history of type 2 diabetes mellitus (DM) who experienced disseminated cutaneous VZV infection followed by multiple cerebral infarcts associated with VZV vasculopathy. Brain magnetic resonance imaging revealed multiple hyperintense lesions over the bilateral deep white matter and basal ganglia. A skin biopsy revealed small-vessel leukocytoclastic vasculitis with neutrophilic, lymphocytic, and eosinophilic infiltration. This case report describes the rare finding of cutaneous leukocytoclastic vasculitis in VZV infection and highlights that VZV infection is an uncommon but critical etiology of cryptogenic stroke in patients with DM.

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Title: Disseminated cutaneous herpes zoster and multiple cerebral infarcts in an adult with diabetes mellitus
Authors: Chun-Fu Lin
Chien-Tai Hong
Wei-Hwa Lee
Dean Wu
Chaur-Jong Hu
Chen-Chih Chung
Publication date: 01-02-2020
Publisher: Springer International Publishing
Keywords: Vasculitis
Vasculitis
Shingles
Leukocytoclastic Vasculitis
Magnetic Resonance Imaging
Magnetic Resonance Imaging
Stroke
Human Alphaherpesvirus 3
Leukocytoclastic Vasculitis
Diabetes
Published in: Journal of NeuroVirology / Issue 1/2020
Print ISSN: 1355-0284
Electronic ISSN: 1538-2443
DOI: https://doi.org/10.1007/s13365-019-00790-7

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Disseminated cutaneous herpes zoster and multiple cerebral infarcts in an adult with diabetes mellitus

Abstract

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Abstract

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