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Neurotherapeutics
Published in: Neurotherapeutics 4/2015

01-10-2015 | Review

Cannabidiol as a Potential Treatment for Anxiety Disorders

Authors: Esther M. Blessing, Maria M. Steenkamp, Jorge Manzanares, Charles R. Marmar

Published in: Neurotherapeutics | Issue 4/2015

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Abstract

Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum drug that in recent years has drawn increasing interest as a treatment for a range of neuropsychiatric disorders. The purpose of the current review is to determine CBD’s potential as a treatment for anxiety-related disorders, by assessing evidence from preclinical, human experimental, clinical, and epidemiological studies. We found that existing preclinical evidence strongly supports CBD as a treatment for generalized anxiety disorder, panic disorder, social anxiety disorder, obsessive–compulsive disorder, and post-traumatic stress disorder when administered acutely; however, few studies have investigated chronic CBD dosing. Likewise, evidence from human studies supports an anxiolytic role of CBD, but is currently limited to acute dosing, also with few studies in clinical populations. Overall, current evidence indicates CBD has considerable potential as a treatment for multiple anxiety disorders, with need for further study of chronic and therapeutic effects in relevant clinical populations.
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Metadata
Title
Cannabidiol as a Potential Treatment for Anxiety Disorders
Authors
Esther M. Blessing
Maria M. Steenkamp
Jorge Manzanares
Charles R. Marmar
Publication date
01-10-2015
Publisher
Springer US
Published in
Neurotherapeutics / Issue 4/2015
Print ISSN: 1933-7213
Electronic ISSN: 1878-7479
DOI
https://doi.org/10.1007/s13311-015-0387-1

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Cannabinoids in the Treatment of Neurological Disorders

Review

Clinical Use of Cannabinoids for Symptom Control in Multiple Sclerosis