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01-06-2017 | Review Article

Updates in primary hyperparathyroidism

Author: Guido Gasparri

Published in: Updates in Surgery | Issue 2/2017

Abstract

This is a review of the latest papers on PHPT with the purpose of assessing the most recent evidence in the management of PHPT and to give updated recommendations for its evaluation, diagnosis, and treatment. I used my personal experience to collect papers that reinforce my ideas for the diagnosis and treatment of PHPT. Perhaps, in the near future, we will have more information about genetics, localization studies, surgical techniques, medical treatments, and statements that we have presented today will be obsolete.

Shindo M, Lee JA, Lubitz CC, McCoy KL, Orloff LA, Tufano RP, Pasieka JL (2016) The changing landscape of primary, secondary, and tertiary hyperparathyroidism: highlights from the american college of surgeons panel, “what’s new for the surgeon caring for patients with hyperparathyroidism. J Am Coll Surg 222:1241–1250CrossRef

Wilhelm SM, Wang TS, Ruan DT, Lee JA, Asa SL, Duh QY, Doherty GM, Herrera MF, Pasieka JL, Perrier ND, Silverberg SJ, Solórzano CC, Sturgeon C, Tublin ME, Udelsman R, Carty SE (2016) The American association of endocrine surgeons guidelines for definitive management of primary hyperparathyroidism. JAMA Surg 151:959–968CrossRefPubMed

Liu JY, Saunders ND, Chen A, Weber CJ, Sharma J (2016) Neuropsychological changes in primary hyperparathyroidism after parathyroidectomy. Am Surg 82:839–845PubMed

Pasieka JL, Parsons L, Jones J (2009) The long-term benefit of parathyroidectomy in primary hyperparathyroidism: a 10-year prospective surgical outcome study. Surgery 146:1006–1013CrossRefPubMed

Pasieka JL, Parsons LL (1998) Prospective surgical outcome study of relief of symptoms following surgery in patients with primary hyperparathyroidism. World J Surg 22:513–518CrossRefPubMed

Sheldon DG, Lee FT, Neil NJ, Ryan JA Jr (2002) Surgical treatment of hyperparathyroidism improves health-related quality of life. Arch Surg 137:1022–1026CrossRefPubMed

Ambrogini E, Cetani F, Cianferotti L, Vignali E, Banti C, Viccica G, Oppo A, Miccoli P, Berti P, Bilezikian JP, Pinchera A, Marcocci C (2007) Surgery or surveillance formild asymptomatic primary hyperparathyroidism: a prospective, randomized clinical trial. J Clin Endocrinol Metab 92:3114–3121CrossRefPubMed

Zanocco K, Angelos P, Sturgeon C (2006) Cost-effectiveness analysis of parathyroidectomy for asymptomatic primary hyperparathyroidism. Surgery 140:874–881CrossRefPubMed

Khan AA, Hanley DA, Rizzoli R, Bollerslev J, Young JE, Rejnmark L, Thakker R, D’Amour P, Paul T, Van Uum S, Shrayyef MZ, Goltzman D, Kaiser S, Cusano NE, Bouillon R, Mosekilde L, Kung AW, Rao SD, Bhadada SK, Clarke BL, Liu J, Duh Q, Lewiecki EM, Bandeira F, Eastell R, Marcocci C, Silverberg SJ, Udelsman R, Davison KS, Potts JT Jr, Brandi ML, Bilezikian JP (2017) Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus. Osteoporos Int 28:1–19CrossRefPubMed

10.

Kluijfhout W, Pasternak JD, Drake F, Beninato T, Gosnell JE, Shen WT, Duh QY, Allen IE, Vriens MR, de Keizer B, Pampaloni MH, Suh I (2016) Use of PET tracers for parathyroid localization: a systematic review and meta-analysis. Langenbecks Arch Surg 401:925–935CrossRefPubMedPubMedCentral

11.

Fortuny JV, Karenovics W, Triponez F, Sadowski SM (2016) Intra-operative indocyanine green angiography of the parathyroid gland. World J Surg 40:2378–2381CrossRef

12.

Fortuny JV, Belfontali V, Sadowski SM, Karenovics W, Guigard S, Triponez F (2016) Parathyroid gland angiography with indocyanine green fluorescence to predict parathyroid function after thyroid surgery. BJS 103:537–543CrossRef

13.

Gasparri G, Palestini N, Freddi M, Sisto G, Camandona M (2015) Parathyroid exploration for primary hyperparathyroidism. In: Gasparri G et al (eds) Springer, Italia, pp 117–32

14.

De Gregorio L, Lubitz CC, Hodin RA, Gaz RD, Parangi S, Phitayakorn R, Stephen AE (2016) The truth about double adenomas: incidence, localization, and intraoperative parathyroid hormone. J Am Coll Surg 222:1044–1052CrossRefPubMed

15.

Mengozzi G (2016) Clinical use of the parathyroid hormone assay. In: Gasparri G et al (eds). Springer, Italia, pp 29–40

16.

Kiernan CM, Schlegel C, Isom C, Kavalukas S, Peters MF, Solórzano CC (2016) Ambulatory bilateral neck exploration forprimary hyperparathyroidism: is it safe? Am J Surg 212:722–727CrossRefPubMed

17.

Siperstein A, Berber E, Barbosa GF, Tsinberg M, Greene AB, Mitchell J, Milas M (2008) Predicting the success of limited exploration for primary hyperparathyroidism using ultrasound, sestamibi, and intraoperative parathyroid hormone: analysis of 1158 cases. Ann Surg 248:420–428PubMed

18.

Norman J, Lopez J, Politz D (2012) Abandoning unilateral parathyroidectomy: why we reversed our position after 15,000 parathyroid operations. J Am Coll Surg 214:260–269CrossRefPubMed

19.

Thier M, Nordenström E, Almquist M, Bergenfelz A (2016) Results of a fifteen-year follow-up program in patients operated with unilateral neck exploration for primary hyperparathyroidism. World J Surg 40:582–588CrossRefPubMed

20.

Rio PD, Vicente D, Maestroni U, Totaro A, Pattacini GM, Avital I, Stojadinovic A, Sianesi M (2013) A comparison of minimally invasive video-assisted parathyroidectomy and traditional parathyroidectomy for parathyroid adenoma. J Cancer 4:458–463CrossRefPubMedPubMedCentral

21.

Wong W, Foo FJ, Lau MI, Sarin A, Kiruparan P (2011) Simplified minimally invasive parathyroidectomy: a series of 100 cases and review of the literature. Ann R Coll Surg Engl 93:290–293CrossRefPubMedPubMedCentral

22.

Garas G, Holsinger FC, Grant DG, Athanasiou T, Arora A, Tolley N (2015) Is robotic parathyroidectomy a feasible and safe alternative to targeted open parathyroidectomy for the treatment of primary hyperparathyroidism? Int J Surg 15:55–60CrossRefPubMed

23.

Tolley N, Garas G, Palazzo F, Prichard A, Chaidas K, Cox J, Darzi A, Arora A (2016) Long-term prospective evaluation comparing robotic parathyroidectomy with minimally invasive open parathyroidectomy for primary hyperparathyroidism. Head Neck 38:300–306CrossRef

24.

Kang J, Fan Y, Guo B, Wu B, Zheng Q (2013) Trans-areola single-site endoscopic parathyroidectomy: report of one case. Surg Innov. 20:16–20CrossRef

25.

Brunaud L, Zhen L, Van Den Heede K, Cuny T, Van-Slycke S (2016) Endoscopic and robotic parathyroidectomy in patients with primary hyperparathyroidism. Gland Surg. 5:352–360CrossRefPubMedPubMedCentral

26.

Javid M, Callender G, Quinn C, Carling T, Donovan P, Udelsman R (2017) Primary hyperparathyroidism with normal baseline intraoperative parathyroid hormone: a challenging population. Surgery 161:493–498CrossRefPubMed

27.

Sosa JA (2016) How best to approach surgery for primary hyperparathyroidism—canwe all agree? JAMA Surg 151:969CrossRefPubMed

28.

Nordenström J (2013) The hunt for the parathyroids. Wiley, Chichester

Title: Updates in primary hyperparathyroidism
Author: Guido Gasparri
Publication date: 01-06-2017
Publisher: Springer Milan
Published in: Updates in Surgery / Issue 2/2017
Print ISSN: 2038-131X
Electronic ISSN: 2038-3312
DOI: https://doi.org/10.1007/s13304-017-0477-1

At a glance: The STEP trials

Springer Medicine

Updates in primary hyperparathyroidism

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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