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Published in: Updates in Surgery 3/2013

01-09-2013 | Review Article

Management of uterine leiomyomas in pregnancy: review of literature

Authors: Salvatore Giovanni Vitale, Alessandro Tropea, Diego Rossetti, Marco Carnelli, Antonio Cianci

Published in: Updates in Surgery | Issue 3/2013

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Abstract

The incidence of uterine myomas in pregnancy is estimated from 0.1 to 3.9 %. Although a lot of women with uterine fibroids bring the pregnancy without adverse events, data provided in the literature suggest that uterine fibromyomas are associated with several complications. The most important clinic question concerns the impact of myoma on pregnancy and, in some cases, the possibility of a surgical treatment that guarantees a good security for the pregnancy course and the conservation of reproductive capacity. Electronic search of Pubmed between 1993 and 2011, using specific keywords. Management of leiomyomas in pregnancy is conservative and limited, when it is necessary, to medical therapy. The main conditions that induce inevitably the surgical procedure are the torsion of pedunculated fibroid or rare cases of necrosis and resultant inflammatory peritoneal reaction. Laparoscopy technique has several advantages in comparison to previous techniques such as best postoperative course with reduction of pain, fast recovery, less hospitalization and, absence of large and unaesthetic scars. The importance of maternal and fetal welfare thus requires a careful evaluation of several factors that, varying from case to case, lead the authors to choose the most appropriate management.
Literature
1.
go back to reference Wallach EE, Vlahos NF (2004) Uterine myomas: an overview of development, clinical features, and management. Obstet Gynecol 104(2):393–406PubMedCrossRef Wallach EE, Vlahos NF (2004) Uterine myomas: an overview of development, clinical features, and management. Obstet Gynecol 104(2):393–406PubMedCrossRef
2.
go back to reference Sunkara SK, Khairy M, El-Toukhy T, Khalaf Y, Coomarasamy A (2010) The effect of intramural fibroids without uterine cavity involvement on the outcome of IVF treatment: a systematic review and meta-analysis. Hum Reprod 25(2):418–429PubMedCrossRef Sunkara SK, Khairy M, El-Toukhy T, Khalaf Y, Coomarasamy A (2010) The effect of intramural fibroids without uterine cavity involvement on the outcome of IVF treatment: a systematic review and meta-analysis. Hum Reprod 25(2):418–429PubMedCrossRef
3.
go back to reference Lee HJ, Norwitz ER, Shaw J (2010) Contemporary Management of Fibroids in Pregnancy. Rev Obstet Gynecol 3(1):20–27PubMed Lee HJ, Norwitz ER, Shaw J (2010) Contemporary Management of Fibroids in Pregnancy. Rev Obstet Gynecol 3(1):20–27PubMed
4.
go back to reference Parker WH (2007) Etiology, symptomatology, and diagnosis of uterine myomas. Fertil Steril 87(4):725–736PubMedCrossRef Parker WH (2007) Etiology, symptomatology, and diagnosis of uterine myomas. Fertil Steril 87(4):725–736PubMedCrossRef
5.
go back to reference Day Baird D, Dunson DB, Hill MC, Cousins D, Schectman JM (2003) High cumulative incidence of uterine leiomyoma in black and white woman: ultrasound evidence. Am J Obstet Gynecol 188(1):100–107CrossRef Day Baird D, Dunson DB, Hill MC, Cousins D, Schectman JM (2003) High cumulative incidence of uterine leiomyoma in black and white woman: ultrasound evidence. Am J Obstet Gynecol 188(1):100–107CrossRef
6.
go back to reference Baloniak B, Slomko Z, Malewski Z, Drews K (2002) The incidence of uterine leiomyomas in pregnancy and their influence upon its course. Ginekol Pl 73(4):260–265 Baloniak B, Slomko Z, Malewski Z, Drews K (2002) The incidence of uterine leiomyomas in pregnancy and their influence upon its course. Ginekol Pl 73(4):260–265
7.
go back to reference De Vivo A, Mancuso A, Giacobbe A, Savasta LM, De Dominici R, Dugo N, Vaiarelli A (2011) Uterine myomas during pregnancy: a longitudinal sonographic study. Ultrasound Obstet Gynecol 37(3):361–365PubMedCrossRef De Vivo A, Mancuso A, Giacobbe A, Savasta LM, De Dominici R, Dugo N, Vaiarelli A (2011) Uterine myomas during pregnancy: a longitudinal sonographic study. Ultrasound Obstet Gynecol 37(3):361–365PubMedCrossRef
8.
go back to reference Benson CB, Chow JS, Chang-Lee W, Hill JA 3rd, Doubilet PM (2001) Outcame of pregnancies in women with uterine leiomyomas identified by sonography in the first trimester. J Clin Ultrasound 29(5):261–264PubMedCrossRef Benson CB, Chow JS, Chang-Lee W, Hill JA 3rd, Doubilet PM (2001) Outcame of pregnancies in women with uterine leiomyomas identified by sonography in the first trimester. J Clin Ultrasound 29(5):261–264PubMedCrossRef
9.
go back to reference Lolis DE, Kalantaridou SN, Makrydimas G, Sotiriadis A, Navrozoglou I, Zikopoulos K, Paraskevaidis EA (2003) Successful myomectomy during pregnancy. Hum Reprod 18(8):1699–1702PubMedCrossRef Lolis DE, Kalantaridou SN, Makrydimas G, Sotiriadis A, Navrozoglou I, Zikopoulos K, Paraskevaidis EA (2003) Successful myomectomy during pregnancy. Hum Reprod 18(8):1699–1702PubMedCrossRef
10.
go back to reference Coronado GD, Marshall LM, Schwartz AM (2000) Complications in pregnancy, labor and delivery with uterine leiomyomas: a population based-study. Obstet Gynecol 95(5):764–769PubMedCrossRef Coronado GD, Marshall LM, Schwartz AM (2000) Complications in pregnancy, labor and delivery with uterine leiomyomas: a population based-study. Obstet Gynecol 95(5):764–769PubMedCrossRef
11.
go back to reference Chuang J, Tsai HW, Hwang JL (2001) Fetal compression syndrome caused by myoma in pregnancy: a case report. Acta Obstet Gynecol Scand 80(5):472–473PubMedCrossRef Chuang J, Tsai HW, Hwang JL (2001) Fetal compression syndrome caused by myoma in pregnancy: a case report. Acta Obstet Gynecol Scand 80(5):472–473PubMedCrossRef
12.
go back to reference Lee HJ, Norwitz ER, Shaw J (2010) Contemporary Management of Fibroids in Pregnancy. Rev Obstet Gynecol 3(1):20–27PubMed Lee HJ, Norwitz ER, Shaw J (2010) Contemporary Management of Fibroids in Pregnancy. Rev Obstet Gynecol 3(1):20–27PubMed
13.
go back to reference Phelan JP (1995) Myomas and Pregnancy. Obstet Gynecol Clin North Am 22(4):801–805PubMed Phelan JP (1995) Myomas and Pregnancy. Obstet Gynecol Clin North Am 22(4):801–805PubMed
14.
go back to reference Exacoustòs C, Rosati P (1993) Ultrasound diagnosis of uterine myomas and complications in pregnancy. Obstet Gynecol 82(1):97–101PubMed Exacoustòs C, Rosati P (1993) Ultrasound diagnosis of uterine myomas and complications in pregnancy. Obstet Gynecol 82(1):97–101PubMed
15.
go back to reference Leach K, Khatain L, Tocce K (2011) First trimester myomectomy as an alternative to termination of pregnancy in a woman with a symptomatic uterine leiomyoma: a case report. J Med Case Rep 5(1):571PubMedCrossRef Leach K, Khatain L, Tocce K (2011) First trimester myomectomy as an alternative to termination of pregnancy in a woman with a symptomatic uterine leiomyoma: a case report. J Med Case Rep 5(1):571PubMedCrossRef
16.
go back to reference Cagnacci A, Pirillo D, Malmusi S, Arangino S, Alessandrini C, Volpe A (2003) Early outcome of myomectomy by laparotomy, minilaparotomy and laparoscopically assisted minilaparotomy. A randomized prospective study. Hum Reprod 18(12):2590–2594CrossRef Cagnacci A, Pirillo D, Malmusi S, Arangino S, Alessandrini C, Volpe A (2003) Early outcome of myomectomy by laparotomy, minilaparotomy and laparoscopically assisted minilaparotomy. A randomized prospective study. Hum Reprod 18(12):2590–2594CrossRef
17.
go back to reference Takeuchi H, Kuwatsuru R (2003) The indications, surgical techniques, and limitations of laparoscopic myomectomy. JSLS 7(2):89–95PubMed Takeuchi H, Kuwatsuru R (2003) The indications, surgical techniques, and limitations of laparoscopic myomectomy. JSLS 7(2):89–95PubMed
18.
go back to reference Sizzi O, Rossetti A, Malzoni M, Minelli L, La Grotta F, Soranna L, Panunzi S, Spagnolo R, Imperato F, Landi S, Fiaccamento A, Stola E (2007) Italian multicenter study on complications of laparoscopic myomectomy. J Minim Invasive Gynecol 14(4):453–462PubMedCrossRef Sizzi O, Rossetti A, Malzoni M, Minelli L, La Grotta F, Soranna L, Panunzi S, Spagnolo R, Imperato F, Landi S, Fiaccamento A, Stola E (2007) Italian multicenter study on complications of laparoscopic myomectomy. J Minim Invasive Gynecol 14(4):453–462PubMedCrossRef
19.
go back to reference Grande N, Catalano GF, Ferrari S, Marana R (2005) Spontaneous uterine rupture at 27 weeks of pregnancy after laparoscopic myomectomy. J Minim Invasive Gynecol 12(4):301PubMedCrossRef Grande N, Catalano GF, Ferrari S, Marana R (2005) Spontaneous uterine rupture at 27 weeks of pregnancy after laparoscopic myomectomy. J Minim Invasive Gynecol 12(4):301PubMedCrossRef
20.
go back to reference Malzoni M, Tinelli R, Cosentino F, Iuzzolino D, Surico D, Reich H (2010) Laparoscopy versus minilaparotomy in women with symptomatic uterine myomas: short-term and fertility results. Fertil Steril 93(7):2368–2373PubMedCrossRef Malzoni M, Tinelli R, Cosentino F, Iuzzolino D, Surico D, Reich H (2010) Laparoscopy versus minilaparotomy in women with symptomatic uterine myomas: short-term and fertility results. Fertil Steril 93(7):2368–2373PubMedCrossRef
21.
go back to reference Yellamareddygari S, Chakrabarti M, Ravuri S, Ahluwalia A (2010) Leaving fibroids at cesarean section, is it safe? Gynecol Surg 7(2):173–175CrossRef Yellamareddygari S, Chakrabarti M, Ravuri S, Ahluwalia A (2010) Leaving fibroids at cesarean section, is it safe? Gynecol Surg 7(2):173–175CrossRef
Metadata
Title
Management of uterine leiomyomas in pregnancy: review of literature
Authors
Salvatore Giovanni Vitale
Alessandro Tropea
Diego Rossetti
Marco Carnelli
Antonio Cianci
Publication date
01-09-2013
Publisher
Springer Milan
Published in
Updates in Surgery / Issue 3/2013
Print ISSN: 2038-131X
Electronic ISSN: 2038-3312
DOI
https://doi.org/10.1007/s13304-013-0198-z

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