Published in:
01-12-2015 | Editorial
The association between methylenetetrahydrofolate reductase gene C677T polymorphisms and breast cancer risk in Chinese population
Authors:
Yadong Wang, Haiyan Yang, Huiyan Gao, Haiyu Wang
Published in:
Tumor Biology
|
Issue 12/2015
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Abstract
With great interest, we read the recent article entitled “Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk in Chinese population: a meta-analysis of 22 case-control studies” published online in Tumor Biology, 2014, 35: 1695–1701. This article suggests that methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism was significantly associated with breast cancer risk in Chinese population. The result is encouraging. Nevertheless, three key issues in this meta-analysis are worth noticing.