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Tumor Biology
Published in: Tumor Biology 11/2014

01-11-2014 | Review

Molecular function and regulation of long non-coding RNAs: paradigms with potential roles in cancer

Authors: Mohammadreza Hajjari, Atefeh Khoshnevisan, Young Kee Shin

Published in: Tumor Biology | Issue 11/2014

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Abstract

Different long non-coding RNAs (lncRNAs) are transcribed within the genome. Although initially argued to be spurious transcriptional noise, these RNAs play important roles in biological pathways, as shown by different studies. Also, there are some reports about the role of lncRNAs in different cancers. They can contribute to the development and progression of cancer by the functioning as oncogene or/and tumor suppressor molecules. In this review, we point to some important lncRNAs as examples which seem to be involved in cancer initiation/progression.
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Metadata
Title
Molecular function and regulation of long non-coding RNAs: paradigms with potential roles in cancer
Authors
Mohammadreza Hajjari
Atefeh Khoshnevisan
Young Kee Shin
Publication date
01-11-2014
Publisher
Springer Netherlands
Published in
Tumor Biology / Issue 11/2014
Print ISSN: 1010-4283
Electronic ISSN: 1423-0380
DOI
https://doi.org/10.1007/s13277-014-2636-z

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