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Insights into Imaging
Published in: Insights into Imaging 4/2018

Open Access 01-08-2018 | Pictorial Review

Abdominal manifestations of IgG4-related disease: a pictorial review

Authors: Christopher Siew Wai Tang, Nishanth Sivarasan, Nyree Griffin

Published in: Insights into Imaging | Issue 4/2018

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Abstract

In the last decade, autoimmune pancreatitis has become recognised as part of a wider spectrum of IgG4-related disease, typically associated with elevated serum IgG4 levels and demonstrating a response to corticosteroid therapy. Radiologically, there is imaging overlap with other benign and neoplastic conditions. This pictorial review discusses the intra-abdominal manifestations of this disease on cross-sectional imaging before and after steroid treatment and the main radiological features which help to distinguish it from other key differentials.

Teaching Points

• Autoimmune pancreatitis is part of a spectrum of IgG4-related disease.
• Diagnosis is based on raised serum IgG4, clinical, radiological and histopathological findings.
• Cross-sectional imaging can demonstrate the typical findings of abdominal IgG4-related disease.
• Cross-sectional imaging can be used to monitor response to corticosteroid treatment.
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Metadata
Title
Abdominal manifestations of IgG4-related disease: a pictorial review
Authors
Christopher Siew Wai Tang
Nishanth Sivarasan
Nyree Griffin
Publication date
01-08-2018
Publisher
Springer Berlin Heidelberg
Published in
Insights into Imaging / Issue 4/2018
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1007/s13244-018-0618-1

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