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Published in: Insights into Imaging 2/2011

Open Access 01-04-2011 | Review

The future of hybrid imaging—part 1: hybrid imaging technologies and SPECT/CT

Authors: Thomas Beyer, Lutz S. Freudenberg, David W. Townsend, Johannes Czernin

Published in: Insights into Imaging | Issue 2/2011

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Abstract

Since the 1990s, hybrid imaging by means of software and hardware image fusion alike allows the intrinsic combination of functional and anatomical image information. This review summarises in three parts the state-of-the-art of dual-technique imaging, with a focus on clinical applications. We will attempt to highlight selected areas of potential improvement of combined imaging technologies and new applications. In this first part, we briefly review the origins of hybrid imaging and comment on the status and future development of single photon emission tomography (SPECT)/computed tomography (CT). In short, we could predict that, within 10 years, we may see all existing dual-technique imaging systems, including SPECT/CT, in clinical routine use worldwide. SPECT/CT, in particular, may evolve into a whole-body imaging technique with supplementary use in dosimetry applications.
Literature
2.
go back to reference Wagner HN (2005) A personal history of nuclear medicine. Springer, London Wagner HN (2005) A personal history of nuclear medicine. Springer, London
4.
go back to reference Jaszczak R (2006) The early years of single photon emission computed tomography (SPECT): an anthology of selected reminiscences. Phys Med Biol 51:R99–R115PubMedCrossRef Jaszczak R (2006) The early years of single photon emission computed tomography (SPECT): an anthology of selected reminiscences. Phys Med Biol 51:R99–R115PubMedCrossRef
5.
go back to reference Wahl RL et al (1993) “Anatometabolic” tumor imaging: fusion of FDG PET with CT or MRI to localize foci of increased activity. J Nucl Med 34:1190–1197PubMed Wahl RL et al (1993) “Anatometabolic” tumor imaging: fusion of FDG PET with CT or MRI to localize foci of increased activity. J Nucl Med 34:1190–1197PubMed
6.
7.
8.
go back to reference Hutton BF, Braun M (2003) Software for image registration: algorithms, accuracy, efficacy. Semin Nucl Med XXXIII(3):180-192 Hutton BF, Braun M (2003) Software for image registration: algorithms, accuracy, efficacy. Semin Nucl Med XXXIII(3):180-192
9.
go back to reference Slomka P, Baum R (2009) Multimodality image registration with software: state-of-the-art. Eur J Nucl Med Mol Imaging 36(Suppl 1):S44–S55PubMedCrossRef Slomka P, Baum R (2009) Multimodality image registration with software: state-of-the-art. Eur J Nucl Med Mol Imaging 36(Suppl 1):S44–S55PubMedCrossRef
10.
go back to reference Blankespoor SC et al (1996) Attenuation correction of SPECT using X-ray CT on an emission-transmission CT system: myocardial perfusion assessment. IEEE Trans Nucl Sci 43:2263–2274CrossRef Blankespoor SC et al (1996) Attenuation correction of SPECT using X-ray CT on an emission-transmission CT system: myocardial perfusion assessment. IEEE Trans Nucl Sci 43:2263–2274CrossRef
11.
go back to reference LaCroix KJ et al (1994) Investigation of the use of X-ray CT images for attenuation correction in SPECT. IEEE Trans Nucl Sci 41:2793–2799CrossRef LaCroix KJ et al (1994) Investigation of the use of X-ray CT images for attenuation correction in SPECT. IEEE Trans Nucl Sci 41:2793–2799CrossRef
12.
go back to reference Tang HR et al (2001) Neuroblastoma imaging using a combined CT scanner-scintillation camera and 131I-MIBG. J Nucl Med 42(2):237–247PubMed Tang HR et al (2001) Neuroblastoma imaging using a combined CT scanner-scintillation camera and 131I-MIBG. J Nucl Med 42(2):237–247PubMed
13.
go back to reference Bocher M et al (2000) Gamma camera-mounted anatomical X-ray tomography: technology, system characteristics and first images. Eur J Nucl Med 27(6):619–627PubMedCrossRef Bocher M et al (2000) Gamma camera-mounted anatomical X-ray tomography: technology, system characteristics and first images. Eur J Nucl Med 27(6):619–627PubMedCrossRef
14.
go back to reference Patton JA, Delbeke D, Sandler MP (2000) Image fusion using an integrated, dual-head coincidence camera with X-ray tube-based attenuation maps. J Nucl Med 41(8):1364–1368PubMed Patton JA, Delbeke D, Sandler MP (2000) Image fusion using an integrated, dual-head coincidence camera with X-ray tube-based attenuation maps. J Nucl Med 41(8):1364–1368PubMed
15.
go back to reference Bailey D (2003) Is PET the future of nuclear medicine? Eur J Nucl Med Mol Imaging 30(7):1045–1046CrossRef Bailey D (2003) Is PET the future of nuclear medicine? Eur J Nucl Med Mol Imaging 30(7):1045–1046CrossRef
17.
go back to reference Gaemperli O et al (2007) Cardiac image fusion from stand-alone SPECT and CT: clinical experience. J Nucl Med 48(5):696–703PubMedCrossRef Gaemperli O et al (2007) Cardiac image fusion from stand-alone SPECT and CT: clinical experience. J Nucl Med 48(5):696–703PubMedCrossRef
18.
go back to reference Even-Sapir E (2005) Imaging of malignant bone involvement by morphologic, scintigraphic, and hybrid modalities. J Nucl Med 46:1356–1367PubMed Even-Sapir E (2005) Imaging of malignant bone involvement by morphologic, scintigraphic, and hybrid modalities. J Nucl Med 46:1356–1367PubMed
19.
go back to reference Chowdhury F, Scarsbrook A (2008) The role of hybrid SPECT-CT in oncology: current and emerging clinical applications. Clin Radiol 63(3):241–251PubMedCrossRef Chowdhury F, Scarsbrook A (2008) The role of hybrid SPECT-CT in oncology: current and emerging clinical applications. Clin Radiol 63(3):241–251PubMedCrossRef
20.
go back to reference Utsunomiya D et al (2006) Added value of SPECT/CT fusion in assessing suspected bone metastasis: comparison with scintigraphy alone and nonfused scintigraphy and CT. Radiology 238(1):264–271PubMedCrossRef Utsunomiya D et al (2006) Added value of SPECT/CT fusion in assessing suspected bone metastasis: comparison with scintigraphy alone and nonfused scintigraphy and CT. Radiology 238(1):264–271PubMedCrossRef
21.
go back to reference Bockisch A et al (2009) Hybrid imaging by SPECT/CT and PET/CT: proven outcomes in cancer imaging. Semin Nucl Med 39(4):276–289PubMedCrossRef Bockisch A et al (2009) Hybrid imaging by SPECT/CT and PET/CT: proven outcomes in cancer imaging. Semin Nucl Med 39(4):276–289PubMedCrossRef
22.
go back to reference Klocke F et al (2003) ACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging—executive summary: a report of the american college of cardiology/american heart association task force on practice guidelines (ACC/AHA/ASNC committee to revise the 1995 guidelines for the clinical use of cardiac radionuclide imaging. J Am Coll Radiol 42:1318–1333CrossRef Klocke F et al (2003) ACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging—executive summary: a report of the american college of cardiology/american heart association task force on practice guidelines (ACC/AHA/ASNC committee to revise the 1995 guidelines for the clinical use of cardiac radionuclide imaging. J Am Coll Radiol 42:1318–1333CrossRef
23.
go back to reference Kaufmann P (2007) 82-Rubidium-the dawn of cardiac PET in Europe? Eur J Nucl Med Mol Imaging 34(12):1963–1964PubMedCrossRef Kaufmann P (2007) 82-Rubidium-the dawn of cardiac PET in Europe? Eur J Nucl Med Mol Imaging 34(12):1963–1964PubMedCrossRef
24.
go back to reference Dondi M et al (2004) Myocardial SPECT: what do we gain from attenuation correction (and when)? Q J Nucl Med 48:181–187 Dondi M et al (2004) Myocardial SPECT: what do we gain from attenuation correction (and when)? Q J Nucl Med 48:181–187
25.
go back to reference Masood Y, Liu Y, Depuey G (2005) Clinical validation of SPECT attenuation correction using x-ray computed tomography-derived attenuation maps: multicenter clinical trial with angiographic correlation. J Nucl Cardiol 12:676–686PubMedCrossRef Masood Y, Liu Y, Depuey G (2005) Clinical validation of SPECT attenuation correction using x-ray computed tomography-derived attenuation maps: multicenter clinical trial with angiographic correlation. J Nucl Cardiol 12:676–686PubMedCrossRef
26.
go back to reference Mariani G et al (2010) A review on the clinical uses of SPECT/CT. Eur J Nucl Med Mol Imaging 37(10):1959–1985PubMedCrossRef Mariani G et al (2010) A review on the clinical uses of SPECT/CT. Eur J Nucl Med Mol Imaging 37(10):1959–1985PubMedCrossRef
27.
go back to reference Gambhir S et al (2009) A novel high-sensitivity rapid-acquisition single-photon cardiac imaging camera. J Nucl Med 50(4):635–643PubMedCrossRef Gambhir S et al (2009) A novel high-sensitivity rapid-acquisition single-photon cardiac imaging camera. J Nucl Med 50(4):635–643PubMedCrossRef
28.
go back to reference Buechel R et al (2010) Real-time breath-hold triggering of myocardial perfusion imaging with a novel cadmium-zinc-telluride detector gamma camera. Eur J Nucl Med Mol Imaging 37(10):1903–1908PubMedCrossRef Buechel R et al (2010) Real-time breath-hold triggering of myocardial perfusion imaging with a novel cadmium-zinc-telluride detector gamma camera. Eur J Nucl Med Mol Imaging 37(10):1903–1908PubMedCrossRef
29.
go back to reference Gaemperli O et al (2007) Validation of a new cardiac image fusion software for three-dimensional integration of myocardial perfusion SPECT and stand-alone 64-slice CT angiography. Eur J Nucl Med Mol Imaging 34(7):1097–1106PubMedCrossRef Gaemperli O et al (2007) Validation of a new cardiac image fusion software for three-dimensional integration of myocardial perfusion SPECT and stand-alone 64-slice CT angiography. Eur J Nucl Med Mol Imaging 34(7):1097–1106PubMedCrossRef
30.
go back to reference Sowards-Emmerd D et al (2010) Image quality advances in flat panel cone-beam CT. In: 2010 Annual Meeting of the Society of Nuclear Medicine. SNM, Salt Lake City Sowards-Emmerd D et al (2010) Image quality advances in flat panel cone-beam CT. In: 2010 Annual Meeting of the Society of Nuclear Medicine. SNM, Salt Lake City
Metadata
Title
The future of hybrid imaging—part 1: hybrid imaging technologies and SPECT/CT
Authors
Thomas Beyer
Lutz S. Freudenberg
David W. Townsend
Johannes Czernin
Publication date
01-04-2011
Publisher
Springer Berlin Heidelberg
Published in
Insights into Imaging / Issue 2/2011
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1007/s13244-010-0063-2

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