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Published in: The Journal of Obstetrics and Gynecology of India 4/2020

01-08-2020 | Coronavirus | Original Article (Editor’s Pick)

Impact of the Coronavirus Infection in Pregnancy: A Preliminary Study of 141 Patients

Authors: Arun Harishchandra Nayak, Deepali Swapnil Kapote, Michelle Fonseca, Niranjan Chavan, Rahul Mayekar, Meenal Sarmalkar, Amarjeet Bawa

Published in: The Journal of Obstetrics and Gynecology of India | Issue 4/2020

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Abstract

Background

The novel coronavirus disease (COVID-19) is the most challenging health crisis that we are facing today. Against the backdrop of this pandemic, it becomes imperative to study the effects of this infection on pregnancy and its outcome. Hence, the present study was undertaken to evaluate the effects of COVID-19 infection on the maternal morbidity and mortality, the course of labour as well as the neonatal outcome.

Materials and Methods

A total of 977 pregnant women were included in the study, from 1st April to 15th May 2020 at a tertiary care hospital. There were 141 women who tested COVID positive and remaining 836 patients were included in the COVID negative group. Findings were compared in both the groups.

Results

The incidence of COVID positive pregnant women was found to be 14.43%. More patients delivered by LSCS in the COVID positive and the COVID negative group (50%) as compared to COVID negative group (47%), (p > 0.05). Low APGAR score (0-3) was observed in 2(1.52%) neonates of COVID positive mothers and in 15 (1.91%) neonates of COVID negative mothers. Overall most of the babies were healthy. Out of all babies tested, 3 were detected positive initially which were retested on day 5 and were found to be negative.

Conclusion

There is no significant effect of COVID infection on maternal and foetal outcome in pregnancy and there is no evidence of vertical transmission of the COVID-19 infection but long-term follow-up of these babies is recommended.
Literature
2.
go back to reference Kerala Defeats Coronavirus; India’s Three COVID-19 Patients Successfully Recover. The Weather Channel. Archived from the original on 18 February 2020. Kerala Defeats Coronavirus; India’s Three COVID-19 Patients Successfully Recover. The Weather Channel. Archived from the original on 18 February 2020.
5.
go back to reference Lauer SA, Grantz KH, Bi Q, Jones FK, Zheng Q, Meredith HR et al. The Incubation Period of Coronavirus Disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Ann Intern Med. 2020;172(9):577–582.CrossRef Lauer SA, Grantz KH, Bi Q, Jones FK, Zheng Q, Meredith HR et al. The Incubation Period of Coronavirus Disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Ann Intern Med. 2020;172(9):577–582.CrossRef
6.
go back to reference Wang W, Tang J, Wei F. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China. J Med Virol. 2020;92(4):441–7.CrossRef Wang W, Tang J, Wei F. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China. J Med Virol. 2020;92(4):441–7.CrossRef
7.
go back to reference Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID19) in China. Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41(2):145–51. Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID19) in China. Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41(2):145–51.
9.
go back to reference Corman VM, Landt O, Kaiser M, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020;25(3):2000045.CrossRef Corman VM, Landt O, Kaiser M, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020;25(3):2000045.CrossRef
10.
go back to reference Chen H, Guo J, Wang C, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395(10226):809–15.CrossRef Chen H, Guo J, Wang C, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395(10226):809–15.CrossRef
11.
go back to reference Schwartz DA, Graham AL. Potential Maternal and Infant Outcomes from (Wuhan) coronavirus 2019-nCoV infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses. 2020;12:1–16.CrossRef Schwartz DA, Graham AL. Potential Maternal and Infant Outcomes from (Wuhan) coronavirus 2019-nCoV infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses. 2020;12:1–16.CrossRef
12.
go back to reference Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J et al. Clinical characteristics of 138 hospitalised patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061–1069.CrossRef Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J et al. Clinical characteristics of 138 hospitalised patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061–1069.CrossRef
13.
go back to reference Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA. 2020;323:1061–9.CrossRef Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA. 2020;323:1061–9.CrossRef
14.
go back to reference Yu N, Li W, Kang Q, et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect Dis. 2020;20(5):559–64.CrossRef Yu N, Li W, Kang Q, et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect Dis. 2020;20(5):559–64.CrossRef
16.
go back to reference Liu H, Liu F, Li J, et al. Clinical and CT imaging features of the COVID-19 pneumonia: focus on pregnant women and children. J Infect. 2020;80:e7–13.CrossRef Liu H, Liu F, Li J, et al. Clinical and CT imaging features of the COVID-19 pneumonia: focus on pregnant women and children. J Infect. 2020;80:e7–13.CrossRef
18.
go back to reference Kennedy CE, Yeh PT, Pandey S et al. Elective cesarean section for women living with HIV: a systematic review of risks and benefits. Aids. 2017;31:1579–91.CrossRef Kennedy CE, Yeh PT, Pandey S et al. Elective cesarean section for women living with HIV: a systematic review of risks and benefits. Aids. 2017;31:1579–91.CrossRef
20.
go back to reference Zhu H, Wang L, Fang C et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020;9:51–60.CrossRef Zhu H, Wang L, Fang C et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020;9:51–60.CrossRef
Metadata
Title
Impact of the Coronavirus Infection in Pregnancy: A Preliminary Study of 141 Patients
Authors
Arun Harishchandra Nayak
Deepali Swapnil Kapote
Michelle Fonseca
Niranjan Chavan
Rahul Mayekar
Meenal Sarmalkar
Amarjeet Bawa
Publication date
01-08-2020
Publisher
Springer India
Published in
The Journal of Obstetrics and Gynecology of India / Issue 4/2020
Print ISSN: 0971-9202
Electronic ISSN: 0975-6434
DOI
https://doi.org/10.1007/s13224-020-01335-3

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