Skip to main content
Top
Published in: The Journal of Obstetrics and Gynecology of India 1/2016

01-10-2016 | Original Article

Large for Gestational Age Births Among South Indian Women: Temporal Trend and Risk Factors from 1996 to 2010

Authors: Lakshmanan Jeyaseelan, Bijesh Yadav, Veerasamy Silambarasan, Reeta Vijayaselvi, Ruby Jose

Published in: The Journal of Obstetrics and Gynecology of India | Special Issue 1/2016

Login to get access

Abstract

Background/Purpose

Mean birth weight is a good health indicator for any population. In the recent past, there have been many reports in the West indicating that there has been an increase in the proportion of large for gestational age (LGA) babies. The objective is to describe the change in the incidence of LGA babies from 1996 to 2010 in South India and the maternal risk factors.

Methods

A rotational sampling scheme was used, i.e., the 12 months of the year were divided into 4 quarters and a month was from each quarter was selected rotationally. All deliveries for that month were considered. Only deliveries that occurred between 28 and 42 weeks of pregnancy were considered. The association between risk variables was studied using multivariable logistic regression.

Results

There were 35,718 deliveries that occurred during these 15-year-study period in the gestational age 28–42 weeks were registered through the outpatient clinics. The incidence of LGA was 9.4 % that has mostly remained at the same level. The incidence of LGA in mothers with gestational diabetes was 6.7, 3 and 17.6 % in overweight, obese and gestational l diabetes mothers. Overweight, obesity in pregnant women and cesarean section were significant risk factors.

Conclusion

Unlike in Western countries, where the incidence of LGA babies has spiraled upward, has remained nearly at the same level over one and a half decades, in South India. The risk factors for giving birth to LGA babies in South India were similar to other studies.
Literature
1.
go back to reference Arbuckle TE, Sherman GJ. An analysis of birth weight by gestational age in Canada. CMAJ 1989;140(2):157–60, 65. Arbuckle TE, Sherman GJ. An analysis of birth weight by gestational age in Canada. CMAJ 1989;140(2):157–60, 65.
4.
go back to reference Oja H, Koiranen M, Rantakallio P. Fitting mixture models to birth weight data: a case study. Biometrics. 1991;47(3):883–97.CrossRefPubMed Oja H, Koiranen M, Rantakallio P. Fitting mixture models to birth weight data: a case study. Biometrics. 1991;47(3):883–97.CrossRefPubMed
5.
go back to reference Blondel B, Bréart G, du Mazaubrun C, et al. The perinatal situation in France. Trends between 1981 and 1995. J Gynecol Obstet Biol Reprod. 1997;26(8):770–80. Blondel B, Bréart G, du Mazaubrun C, et al. The perinatal situation in France. Trends between 1981 and 1995. J Gynecol Obstet Biol Reprod. 1997;26(8):770–80.
6.
go back to reference Kramer MS, Morin I, Yang H, et al. Why are babies getting bigger? Temporal trends in fetal growth and its determinants. J Pediatr. 2002;141(4):538–42.CrossRefPubMed Kramer MS, Morin I, Yang H, et al. Why are babies getting bigger? Temporal trends in fetal growth and its determinants. J Pediatr. 2002;141(4):538–42.CrossRefPubMed
7.
go back to reference Hadfield RM, Lain SJ, Simpson JM, et al. Are babies getting bigger? An analysis of birthweight trends in New South Wales, 1990-2005. Med J Aust. 2009;190(6):312–5.PubMed Hadfield RM, Lain SJ, Simpson JM, et al. Are babies getting bigger? An analysis of birthweight trends in New South Wales, 1990-2005. Med J Aust. 2009;190(6):312–5.PubMed
9.
go back to reference Bryant DR, Leonardi MR, Landwehr JB, et al. Limited usefulness of fetal weight in predicting neonatal brachial plexus injury. Am J Obstet Gynecol. 1998;179(3 Pt 1):686–9.CrossRefPubMed Bryant DR, Leonardi MR, Landwehr JB, et al. Limited usefulness of fetal weight in predicting neonatal brachial plexus injury. Am J Obstet Gynecol. 1998;179(3 Pt 1):686–9.CrossRefPubMed
10.
11.
go back to reference Spellacy WN, Miller S, Winegar A, et al. Macrosomia—maternal characteristics and infant complications. Obstet Gynecol. 1985;66(2):158–61.PubMed Spellacy WN, Miller S, Winegar A, et al. Macrosomia—maternal characteristics and infant complications. Obstet Gynecol. 1985;66(2):158–61.PubMed
12.
go back to reference Das UG, Sysyn GD. Abnormal fetal growth: intrauterine growth retardation, small for gestational age, large for gestational age. Pediatr Clin North Am. 2004;51(3):639–54.CrossRefPubMed Das UG, Sysyn GD. Abnormal fetal growth: intrauterine growth retardation, small for gestational age, large for gestational age. Pediatr Clin North Am. 2004;51(3):639–54.CrossRefPubMed
13.
go back to reference Ørskou J, Kesmodel U, Henriksen TB, et al. An increasing proportion of infants weigh more than 4000 grams at birth. Acta Obstet Gynecol Scand. 2001;80(10):931–6.CrossRefPubMed Ørskou J, Kesmodel U, Henriksen TB, et al. An increasing proportion of infants weigh more than 4000 grams at birth. Acta Obstet Gynecol Scand. 2001;80(10):931–6.CrossRefPubMed
14.
go back to reference Lawoyin TO. A prospective study on some factors which influence the delivery of large babies. J Trop Med Hyg. 1993;96(6):352–6.PubMed Lawoyin TO. A prospective study on some factors which influence the delivery of large babies. J Trop Med Hyg. 1993;96(6):352–6.PubMed
15.
go back to reference Zetterström J, López A, Anzén B, et al. Anal sphincter tears at vaginal delivery: risk factors and clinical outcome of primary repair. Obstet Gynecol. 1999;94(1):21–8.PubMed Zetterström J, López A, Anzén B, et al. Anal sphincter tears at vaginal delivery: risk factors and clinical outcome of primary repair. Obstet Gynecol. 1999;94(1):21–8.PubMed
16.
go back to reference Kumar VS, Jeyaseelan L, Sebastian T, et al. New birth weight reference standards customised to birth order and sex of babies from South India. BMC Pregnancy Childbirth. 2013;13:38.CrossRefPubMedPubMedCentral Kumar VS, Jeyaseelan L, Sebastian T, et al. New birth weight reference standards customised to birth order and sex of babies from South India. BMC Pregnancy Childbirth. 2013;13:38.CrossRefPubMedPubMedCentral
17.
go back to reference Hadlock FP, Harrist RB, Martinez-Poyer J. In utero analysis of fetal growth: a sonographic weight standard. Radiology. 1991;181(1):129–33.CrossRefPubMed Hadlock FP, Harrist RB, Martinez-Poyer J. In utero analysis of fetal growth: a sonographic weight standard. Radiology. 1991;181(1):129–33.CrossRefPubMed
19.
go back to reference Mehta M, Pattanayak RD. Follow-up for improving psychological well-being for women after a miscarriage: RHL Commentary (last revised: 1 January 2013). The WHO Reproductive Health Library; Geneva: World Health Organization. Mehta M, Pattanayak RD. Follow-up for improving psychological well-being for women after a miscarriage: RHL Commentary (last revised: 1 January 2013). The WHO Reproductive Health Library; Geneva: World Health Organization.
20.
go back to reference WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004;363(9403):157–63.CrossRef WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004;363(9403):157–63.CrossRef
21.
go back to reference Irion O, Boulvain M. Induction of labour for suspected fetal macrosomia. Cochrane Database Syst Rev 2000;(2):CD000938. Irion O, Boulvain M. Induction of labour for suspected fetal macrosomia. Cochrane Database Syst Rev 2000;(2):CD000938.
22.
go back to reference Giapros V, Evagelidou E, Challa A, et al. Serum adiponectin and leptin levels and insulin resistance in children born large for gestational age are affected by the degree of overweight. Clin Endocrinol (Oxf). 2007;66(3):353–9.CrossRef Giapros V, Evagelidou E, Challa A, et al. Serum adiponectin and leptin levels and insulin resistance in children born large for gestational age are affected by the degree of overweight. Clin Endocrinol (Oxf). 2007;66(3):353–9.CrossRef
23.
go back to reference Surkan PJ, Hsieh C-C, Johansson ALV, et al. Reasons for increasing trends in large for gestational age births. Obstet Gynecol. 2004;104(4):720–6.CrossRefPubMed Surkan PJ, Hsieh C-C, Johansson ALV, et al. Reasons for increasing trends in large for gestational age births. Obstet Gynecol. 2004;104(4):720–6.CrossRefPubMed
24.
go back to reference Hedderson MM, Weiss NS, Sacks DA, et al. Pregnancy weight gain and risk of neonatal complications: macrosomia, hypoglycemia, and hyperbilirubinemia. Obstet Gynecol. 2006;108(5):1153–61.CrossRefPubMed Hedderson MM, Weiss NS, Sacks DA, et al. Pregnancy weight gain and risk of neonatal complications: macrosomia, hypoglycemia, and hyperbilirubinemia. Obstet Gynecol. 2006;108(5):1153–61.CrossRefPubMed
25.
go back to reference Siega-Riz AM, Viswanathan M, Moos M-K, et al. A systematic review of outcomes of maternal weight gain according to the Institute of Medicine recommendations: birthweight, fetal growth, and postpartum weight retention. Am J Obstet Gynecol. 2009;201(4):339.e1-14.CrossRefPubMed Siega-Riz AM, Viswanathan M, Moos M-K, et al. A systematic review of outcomes of maternal weight gain according to the Institute of Medicine recommendations: birthweight, fetal growth, and postpartum weight retention. Am J Obstet Gynecol. 2009;201(4):339.e1-14.CrossRefPubMed
26.
go back to reference Ehrenberg HM, Dierker L, Milluzzi C, et al. Prevalence of maternal obesity in an urban center. Am J Obstet Gynecol. 2002;187(5):1189–93.CrossRefPubMed Ehrenberg HM, Dierker L, Milluzzi C, et al. Prevalence of maternal obesity in an urban center. Am J Obstet Gynecol. 2002;187(5):1189–93.CrossRefPubMed
27.
go back to reference Isaacs JD, Magann EF, Martin RW, et al. Obstetric challenges of massive obesity complicating pregnancy. J Perinatol. 1994;14(1):10–4.PubMed Isaacs JD, Magann EF, Martin RW, et al. Obstetric challenges of massive obesity complicating pregnancy. J Perinatol. 1994;14(1):10–4.PubMed
28.
go back to reference Galtier-Dereure F, Boegner C, Bringer J. Obesity and pregnancy: complications and cost. Am J Clin Nutr. 2000;71(5 Suppl):1242S–8S.PubMed Galtier-Dereure F, Boegner C, Bringer J. Obesity and pregnancy: complications and cost. Am J Clin Nutr. 2000;71(5 Suppl):1242S–8S.PubMed
29.
go back to reference Sebire NJ, Jolly M, Harris JP, et al. Maternal obesity and pregnancy outcome: a study of 287,213 pregnancies in London. Int J Obes Relat Metab Disord. 2001;25(8):1175–82.CrossRefPubMed Sebire NJ, Jolly M, Harris JP, et al. Maternal obesity and pregnancy outcome: a study of 287,213 pregnancies in London. Int J Obes Relat Metab Disord. 2001;25(8):1175–82.CrossRefPubMed
30.
go back to reference Crane SS, Wojtowycz MA, Dye TD, et al. Association between pre-pregnancy obesity and the risk of cesarean delivery. Obstet Gynecol. 1997;89(2):213–6.CrossRefPubMed Crane SS, Wojtowycz MA, Dye TD, et al. Association between pre-pregnancy obesity and the risk of cesarean delivery. Obstet Gynecol. 1997;89(2):213–6.CrossRefPubMed
31.
go back to reference Johnson SR, Kolberg BH, Varner MW, et al. Maternal obesity and pregnancy. Surg Gynecol Obstet. 1987;164(5):431–7.PubMed Johnson SR, Kolberg BH, Varner MW, et al. Maternal obesity and pregnancy. Surg Gynecol Obstet. 1987;164(5):431–7.PubMed
32.
go back to reference Bianco AT, Smilen SW, Davis Y, et al. Pregnancy outcome and weight gain recommendations for the morbidly obese woman. Obstet Gynecol. 1998;91(1):97–102.CrossRefPubMed Bianco AT, Smilen SW, Davis Y, et al. Pregnancy outcome and weight gain recommendations for the morbidly obese woman. Obstet Gynecol. 1998;91(1):97–102.CrossRefPubMed
33.
go back to reference Cnattingius S, Bergström R, Lipworth L, et al. Prepregnancy weight and the risk of adverse pregnancy outcomes. N Engl J Med. 1998;338(3):147–52.CrossRefPubMed Cnattingius S, Bergström R, Lipworth L, et al. Prepregnancy weight and the risk of adverse pregnancy outcomes. N Engl J Med. 1998;338(3):147–52.CrossRefPubMed
34.
go back to reference Cedergren MI. Maternal morbid obesity and the risk of adverse pregnancy outcome. Obstet Gynecol. 2004;103(2):219–24.CrossRefPubMed Cedergren MI. Maternal morbid obesity and the risk of adverse pregnancy outcome. Obstet Gynecol. 2004;103(2):219–24.CrossRefPubMed
35.
go back to reference Lederman SA, Paxton A. Maternal reporting of pre pregnancy weight and birth outcome: consistency and completeness compared with the clinical record. Maternal Child Health J. 1998;2(2):123–6.CrossRef Lederman SA, Paxton A. Maternal reporting of pre pregnancy weight and birth outcome: consistency and completeness compared with the clinical record. Maternal Child Health J. 1998;2(2):123–6.CrossRef
Metadata
Title
Large for Gestational Age Births Among South Indian Women: Temporal Trend and Risk Factors from 1996 to 2010
Authors
Lakshmanan Jeyaseelan
Bijesh Yadav
Veerasamy Silambarasan
Reeta Vijayaselvi
Ruby Jose
Publication date
01-10-2016
Publisher
Springer India
Published in
The Journal of Obstetrics and Gynecology of India / Issue Special Issue 1/2016
Print ISSN: 0971-9202
Electronic ISSN: 0975-6434
DOI
https://doi.org/10.1007/s13224-015-0765-y

Other articles of this Special Issue 1/2016

The Journal of Obstetrics and Gynecology of India 1/2016 Go to the issue