Myasthenia Gravis Following Excision of a Large Thymoma

Excerpt

A 63-year-old gentleman presented with a history of fever and weight loss for 6 months and nonproductive cough for 3 months. There was no history of hypertension, heart disease, TB, or asthma. On examination, he had decreased breath sound on right mid zone. His neurological and musculoskeletal examination was normal and he did not have any lymphadenopathy. An initial chest radiograph showed an anterior mediastinal mass extending to the right of the ascending aorta. A contrast computed tomographic (CT) scan showed a lobulated 15×12cm heterogeneous soft tissue mass in the anterior mediastinum. There were no areas of the chest wall or pericardial invasion or lymphadenopathy (Fig. 1). Whole-body PET-CT showed FDG avid, heterogeneously enhancing soft tissue mass lesion measuring ~10.1 × 7.1 × 11.8 cm in the anterior mediastinum, displacing and compressing anterior segment of the right upper lobe and medial segment of the right middle lobe. No other FDG avid lesion in the body was seen.

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