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Indian Journal of Surgical Oncology
Published in: Indian Journal of Surgical Oncology 3/2019

01-09-2019 | Soft Tissue Sarcoma | Case Report

Rare Case Presentation of Leiomyosarcoma as IVC Thrombus

Authors: K. P. Suneetha, Sunil Basappa Gudaganatti, J. Gayathri

Published in: Indian Journal of Surgical Oncology | Issue 3/2019

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Background

Leiomyosarcoma (LMS) of vascular origin is uncommon. This leiomyosarcoma is seen occurring from the tunica media of major blood vessels. Leiomyosarcoma of venous origin is five times more common those of arterial origin. Most cases are presented in woman with a median age of 50 years [1]. We are presenting a case where histopathology was instrumental in making the diagnosis of LMS in the thrombus and confirmed by IHC.
A 46-year old female presented with bilateral swelling of lower limbs and distention of abdomen. Her CT, MRI, and color Doppler were suggestive of IVC, hepatic, and renal vein thrombosis. Histopathology of thrombus revealed leiomyosarcoma and was confirmed by IHC. Conservative treatment was given and asked for a regular follow-up. This case report gives us an opportunity to think of a differential diagnosis in a patient presenting with IVC thrombus
Literature
1.
Yessica Margarita Gonzalez-Cantu et al (2010) Leiomyosarcoma of vascular origin:case report. Case Rep Clin Pathol 2(4)
2.
Weiss SW, Goldblum JR (2008) Leiomyosarcoma in Enzinger and Weiss’s soft tissue tumors, 7th edn. Mosby, St.Louis
3.
Alexander A, Rehders A, Raffel A, Poremba C, Knoefel WT, Eisenberger CF (2009) Leiomyosarcoma of the inferior vena cava: radical surgery and vascular reconstruction. World J Surg Oncol 7:56CrossRef
4.
Perl L (1871) Leiomyosarcoma of inferior vena cava. Virchows Arch Pathol Anat 53:378–383CrossRef
5.
Dzsinich et al (1992) Primary leiomyosarcomas: a rare but lethal disease. J Vasc Surg 15(4):595–603CrossRef
Metadata
Title
Rare Case Presentation of Leiomyosarcoma as IVC Thrombus
Authors
K. P. Suneetha
Sunil Basappa Gudaganatti
J. Gayathri
Publication date
01-09-2019
Publisher
Springer India
Published in
Indian Journal of Surgical Oncology / Issue 3/2019
Print ISSN: 0975-7651
Electronic ISSN: 0976-6952
DOI
https://doi.org/10.1007/s13193-019-00939-0

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