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Translational Behavioral Medicine
Published in: Translational Behavioral Medicine 3/2014

01-09-2014 | Original research

The EARLY trials: a consortium of studies targeting weight control in young adults

Published in: Translational Behavioral Medicine | Issue 3/2014

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Abstract

Young adulthood has been identified as a high-risk period for the development of obesity but few interventions have been tested in this population. One way to escalate our learning about effective interventions is to test a number of interventions simultaneously as a consortium of research trials. This paper describes the Early Adult Reduction of weight through LifestYle intervention (EARLY) trials. Seven research sites were funded to conduct intervention trials, agreeing to test similar primary outcomes and cooperating to use a set of common measurement tools. The EARLY consortium was able to work cooperatively using an executive committee, a steering committee, workgroups and subcommittees to help direct the common work and implement a set of common protocol and measurement tools for seven independent but coordinated weight-related intervention trials. Using a consortium of studies to help young adults reach or maintain a healthy weight will result in increased efficiency and speed in understanding the most effective intervention strategies.
Literature
1.
Finkelstein E, Trogdon J, Cohen J, et al. Annual medical spending attributable to obesity: payer-and service-specific estimates. Health Aff. 2009; 28(5): w822-w831.CrossRef
2.
Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA J Am Med Assoc. 2012; 307(5): 483-490.CrossRef
3.
Finkelstein EA, Khavjou OA, Thompson H, et al. Obesity and severe obesity forecasts through 2030. Am J Prev Med. 2012; 42(6): 563-570.PubMedCrossRef
4.
Wang YC, McPherson K, Marsh T, Gortmaker SL, Brown M. Health and economic burden of the projected obesity trends in the USA and the UK. Lancet. 2011; 378(9793): 815-825.PubMedCrossRef
5.
Williamson DF, Kahn HS, Remington PL, Anda RF. The 10-year incidence of overweight and major weight gain in US adults. Arch Intern Med. 1990; 150: 665-672.PubMedCrossRef
6.
Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999–2010. JAMA J Am Med Assoc. 2012; 307(5): 491-497.CrossRef
7.
Lewis CE, Jacobs DR Jr, McCreath H, et al. Weight gain continues in the 1990s: 10-year trends in weight and overweight from the CARDIA study. Coronary artery risk development in young adults. Am J Epidemiol. 2000; 151(12): 1172-1181.PubMedCrossRef
8.
Ford E, Capewell S. Coronary heart disease mortaility among young adults in the U.S. from 1980 through 2002. Concealed leveling of mortality rates. J Am Coll Cardiol. 2007; 50: 2128-2132.PubMedCrossRef
9.
Jones DS, Greene JA. The decline and rise of coronary heart disease: understanding public health catastrophism. Am J Public Health. 2013; 103(7): 1207-1218.PubMedCrossRef
10.
Lloyd-Jones DM, Liu K, Colangelo LA, et al. Consistently stable or decreased body mass index in young adulthood and longitudinal changes in metabolic syndrome components: the Coronary Artery Risk Development in Young Adults Study. Circulation. 2007; 115(8): 1004-1011.PubMedCrossRef
11.
Daviglus ML, Liu K, Pirzada A, et al. Cardiovascular risk profile earlier in life and Medicare costs in the last year of life. Arch Intern Med. 2005; 165(9): 1028-1034.PubMedCrossRef
12.
13.
Yeh HC, Clark JM, Emmons KE, et al. Independent but coordinated trials: insights from the practice-based opportunities for weight reduction trials collaborative research group. Clin Trials. 2010; 7(4): 322-332.PubMedCrossRefPubMedCentral
14.
Lytle LA, Nanney MS, Laska MN, Linde JA, Sevcik SM, Petrich, CA. Designing a weight gain prevention trial for young adults: the CHOICES study. American Journal of Health Education. 2014; in press.
15.
Wing RR, Tate DF, Gorin AA, Raynor HA, Fava JL. A self-regulation program for maintenance of weight loss. N Engl J Med. 2006; 355(15): 1563-1571.PubMedCrossRef
16.
Bennett LM GH, Levine-Finley S. Collaboration & Team Science: A field guide. 2010.
17.
Belle SH, Czaja SJ, Schulz R, et al. Using a new taxonomy to combine the uncombinable: integrating results across diverse interventions. Psychology Aging. 2003; 18(3): 396-405.PubMedCrossRefPubMedCentral
18.
Michie S, Johnston M, Abraham C, et al. Making psychological theory useful for implementing evidence based practice: a consensus approach. Qual Saf Health Care. 2005; 14(1): 26-33.PubMedCrossRefPubMedCentral
19.
Michie S, Ashford S, Sniehotta FF, Dombrowski SU, Bishop A, French DP. A refined taxonomy of behaviour change techniques to help people change their physical activity and healthy eating behaviours: the CALO-RE taxonomy. Psychol Health. 2011; 26(11): 1479-1498.PubMedCrossRef
20.
CARDIA Study. CARDIA III Year 5 (1990–1991): Sociodemographic Questionnaire. CARDIA III Year 5 (1990–1991). Accessed 28 July 2010.
21.
22.
NCI. Diet History Questionnaire: National Cancer Institute. National Institutes of Health; 2007.
23.
Nelson MC, Lytle LA. Development and evaluation of a brief screener to estimate fast-food and beverage consumption among adolescents. J Am Diet Assoc. 2009; 109(4): 730-734.PubMedCrossRefPubMedCentral
24.
CITY Study. From formative work/focus group questions. Personal communication with Pao-Hwa Lin ed. August 4, 2010.
25.
French S, Jeffery R, Murray D. Is dieting good for you? Prevalence, duration, and associated weight and behaviour changes for specific weight loss strategies over four years in US adults. Int J Obes. 1999; 23: 320-327.CrossRef
26.
Linde J, Jeffery R, French S, Pronk N, Boyle R. Self-weighing in weight gain prevention and weight loss trials. Ann Behav Med. 2005; 30: 210-216.PubMedCrossRef
27.
Raynor D, Phelan S, Hill J, Wing R. Television viewing and long-term weight maintenance: Results from the national weight control registry. Obes Res. 2006; 14: 1816-1824.CrossRef
28.
Centers for Disease Control and Prevention. Behavioral Risk Factor Surveillance System Survey Questionnaire. 2009.
29.
30.
Radloff LS. The CES-D scale: A self-report depression scale for research in the general population. Appl Psychol Meas. 1977; 1: 385-401.CrossRef
31.
Andresen EM, Malmgren JA, Carter WB, Patrick DL. Screening for depression in well older adults: evaluation of a short form of the CES-D (Center for Epidemiologic Studies Depression Scale). Am J Prev Med. 1994; 10(2): 77-84.
32.
33.
Buysse D, Reynolds C, Monk T, Berman S, Kupfer D. The Pittsburg sleep quality index (PSQI): a new instrument for psychiatric research and practice. Psychiatry Res. 1989; 28: 193-213.PubMedCrossRef
34.
35.
Sallis J, Kerr J, Carlson J, et al. Evaluating a brief self-report measure of neighborhood environments for physical activity research and surveillance: Physical activity neighborhood environment scale (PANES). J Phys Act Health. 2010; 7: 533-540.PubMed
36.
Paffenbarger R, Wing A, Hyde R. Physical activity as an index of heart attack risk in college alumni. Am J Epidemiol. 1978; 108: 161-175.PubMed
37.
38.
CARDIA Study. CARDIA VIII, year 25, Sedentary Behavior Questionnaire. E-mail communication with John Jakicic. February 11, 2010.
39.
Rosenburg D, Norman G, Wagner N, Patrick D, Calfas K, Sallis J. Reliability and validity of the sedentary behavior questionnaire (SBQ) for adults. J Phys Act Health. 2010; 7(6): 697-705.
40.
VanWormer J, Martinez AM, Cosentino D, Pronk NP. Satisfaction with a weight loss program: what matters? Am J Health Promot. 2010; 24(4): 238-245.PubMedCrossRef
41.
Baldwin AS, Rothman AJ, Hertel AW, Keenan NK, Jeffery RW. Longitudinal associations between people's cessation-related experiences and their satisfaction with cessation. Psychol Health. 2009; 24(2): 187-201.
Metadata
Title
The EARLY trials: a consortium of studies targeting weight control in young adults
Publication date
01-09-2014
Published in
Translational Behavioral Medicine / Issue 3/2014
Print ISSN: 1869-6716
Electronic ISSN: 1613-9860
DOI
https://doi.org/10.1007/s13142-014-0252-5

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