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Published in: Nuclear Medicine and Molecular Imaging 4/2021

01-08-2021 | Review

Transarterial Radioembolization Agents: a Review of the Radionuclide Agents and the Carriers

Authors: Aysheh Alrfooh, Aditi Patel, Sandeep Laroia

Published in: Nuclear Medicine and Molecular Imaging | Issue 4/2021

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Abstract

Liver tumors, both primary and secondary to metastatic disease, remain a major challenge, with an increasing incidence. In this context, taking advantage of the dual blood supply of the liver, and the fact that liver tumors derive majority of their blood supply from the hepatic artery, intraarterial therapies are gaining popularity. Intraarterial liver-directed therapy (IALDT) is the option when the surgery is not feasible due to the number of metastases or for other reasons. Transarterial radioembolization (TARE) is a specific type of IALDT, where a carrier particle/microsphere is labeled with a radioactive substance and then is injected into hepatic artery for therapeutic purposes. As this field is rapidly evolving, with multiple agents being investigated and being introduced into clinical practice, it is hard for the practitioners and researchers to encompass all the available information concisely. This article aims to present a comprehensive review of the prominent TARE technologies.
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Metadata
Title
Transarterial Radioembolization Agents: a Review of the Radionuclide Agents and the Carriers
Authors
Aysheh Alrfooh
Aditi Patel
Sandeep Laroia
Publication date
01-08-2021
Publisher
Springer Singapore
Published in
Nuclear Medicine and Molecular Imaging / Issue 4/2021
Print ISSN: 1869-3474
Electronic ISSN: 1869-3482
DOI
https://doi.org/10.1007/s13139-021-00709-3

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