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Nuclear Medicine and Molecular Imaging
Published in: Nuclear Medicine and Molecular Imaging 4/2018

01-08-2018 | Case Report

Bone and Calcified Soft Tissue Metastases of Medullary Thyroid Carcinoma Better Characterized on 18F-Fluoride PET/CT than on 68Ga-Dotatate PET/CT

Authors: Paulo Schiavom Duarte, Luciana Audi de Castroneves, Heitor Naoki Sado, Marcelo Tatit Sapienza, Ana Amélia Fialho de Oliveira Hoff, Carlos Alberto Buchpiguel

Published in: Nuclear Medicine and Molecular Imaging | Issue 4/2018

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Abstract

Herein, we report a case of a 19-year-old man with multiple endocrine neoplasia type 2B (MEN2B) and medullary thyroid carcinoma (MTC) diagnosed when he was 12 years of age. The patient had previously undergone total thyroidectomy, cervical radiotherapy, and chemotherapy. He progressed with known bone, pulmonary, and lymph node metastases and was scanned with 18F-fluoride (18F-NaF) and 68Ga-dotatate whole-body positron emission tomography/computed tomography (PET/CT) for metastatic disease monitoring. We found that the MTC bone metastases and soft tissue calcified metastases were better characterized on 18F-NaF PET/CT than on 68Ga-dotatate PET/CT. This case illustrates that the 18F-NaF PET/CT could be helpful not only to the detection of bone metastases but also to the detection of calcified soft tissue metastases in patients with MTC.
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Metadata
Title
Bone and Calcified Soft Tissue Metastases of Medullary Thyroid Carcinoma Better Characterized on 18F-Fluoride PET/CT than on 68Ga-Dotatate PET/CT
Authors
Paulo Schiavom Duarte
Luciana Audi de Castroneves
Heitor Naoki Sado
Marcelo Tatit Sapienza
Ana Amélia Fialho de Oliveira Hoff
Carlos Alberto Buchpiguel
Publication date
01-08-2018
Publisher
Springer Berlin Heidelberg
Published in
Nuclear Medicine and Molecular Imaging / Issue 4/2018
Print ISSN: 1869-3474
Electronic ISSN: 1869-3482
DOI
https://doi.org/10.1007/s13139-018-0527-8

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