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Canadian Journal of Anesthesia/Journal canadien d'anesthésie

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06-07-2022 | Opioids | Correspondence

In reply: Nitrous oxide can help reduce length of stay in the postanesthesia care unit

Authors: Karuna Wongtangman, MD, Michael Blank, cand. med., Matthias Eikermann, MD, PhD

Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Issue 9/2022

Excerpt

We appreciate Drs Mraovic, Timko, and Simurina’s expertise and comments on our paper.^1,2 Our group reported that nitrous oxide (N₂O) use had the beneficial effect of decreasing postanesthesia care unit (PACU) length of stay (LOS). We observed a dose-dependent effect that was already relevant when N₂O was used only at the end of the case (resulting in a very low median N₂O concentration). …

Mraovic B, Timko NJ, Simurina T. Nitrous oxide and length of stay in the postanesthesia care unit. Can J Anesth 2022. https://doi.org/10.1007/s12630-022-02284-3.

Obeidat SS, Wongtangman K, Blank M, et al. The association of nitrous oxide on length of stay in the postanesthesia care unit: a retrospective observational study. Can J Anesth 2021; 68: 1630–40. https://doi.org/10.1007/s12630-021-02067-2CrossRefPubMed

Roth J V. Chronic pain and the opioid epidemic: are we ignoring the potential benefits of nitrous oxide? Anesth Analg 2018; 126: 1423–4. https://doi.org/10.1213/ANE.0000000000002710CrossRefPubMed

Mraovic B, Simurina T, Gan TJ. Nitrous oxide added at the end of isoflurane anesthesia hastens early recovery without increasing the risk for postoperative nausea and vomiting: a randomized clinical trial. Can J Anesth 2018; 65: 162–9. https://doi.org/10.1007/s12630-017-1013-yCrossRefPubMed

Myles PS, Chan MT, Kasza J, et al. Severe nausea and vomiting in the evaluation of nitrous oxide in the gas mixture for anesthesia II trial. Anesthesiology 2016; 124: 1032–40. https://doi.org/10.1097/ALN.0000000000001057CrossRefPubMed

Title: In reply: Nitrous oxide can help reduce length of stay in the postanesthesia care unit
Authors: Karuna Wongtangman, MD
Michael Blank, cand. med.
Matthias Eikermann, MD, PhD
Publication date: 06-07-2022
Publisher: Springer International Publishing
Keywords: Opioids
Opioids
Care
Postoperative Nausea and Vomiting
General Anesthesia
Nitrous Oxide
Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Issue 9/2022
Print ISSN: 0832-610X
Electronic ISSN: 1496-8975
DOI: https://doi.org/10.1007/s12630-022-02285-2

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In reply: Nitrous oxide can help reduce length of stay in the postanesthesia care unit

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