Skip to main content
Top
Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie 6/2012

01-06-2012 | Reports of Original Investigations

Influences observed on incidence and reporting of medication errors in anesthesia

Authors: Lebron Cooper, MD, Neil DiGiovanni, MD, Lucy Schultz, RN, Ashley M. Taylor, PharmD, Bobby Nossaman, MD

Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Issue 6/2012

Login to get access

Abstract

Background

Medication errors are a common occurrence during the conduct of anesthesia (one in 113-450 patients). Several factors contribute to medication errors in anesthesia, including experience of the anesthesia provider, severity of comorbidities, and type of procedure. The inexperience of anesthesia providers-in-training also leads to increased error rates. This prospective observational study repeats and extends previous work by Webster et al. and Llewellyn et al. examining the role of comorbidities, type of case, and level of provider experience on the incidence of medication errors.

Methods

After Institutional Review Board review and exemption from informed consent, medication error reporting forms were attached to every anesthetic record during a six-month period. All providers were asked to return the forms for every anesthetic, on a strictly voluntary and anonymous basis, and to record the occurrence of medication errors. If providers indicated that a medication error had occurred, additional details about the event were obtained anonymously.

Results

There were 8,777 (83%) responses obtained in a review of 10,574 case forms. A medication error was reported in 35 forms, with an additional 17 forms indicating a medication pre-error or near miss, resulting in 52 (0.49%) errors/pre-errors or a reported incidence of 1:203 anesthetics. Most case types were observed to have a statistically significant increase in reported medication errors. Reported errors by type of anesthesia provider were categorized into anesthesia provider-in-training group and the experienced provider group. The anesthesia provider-in-training group reported a twofold increase in the rate of errors, with the most frequently reported errors being incorrect dose and substitution.

Conclusion

This study suggests that case type, American Society of Anesthesiologists’ classification, and level of provider experience play a role on the rate of medication errors. The results of this study are in agreement with previously reported error rates.
Appendix
Available only for authorised users
Literature
1.
go back to reference Webster CS, Merry AF, Larsson L, McGrath KA, Weller J. The frequency and nature of drug administration error during anaesthesia. Anaesth Intensive Care 2001; 29: 494-500.PubMed Webster CS, Merry AF, Larsson L, McGrath KA, Weller J. The frequency and nature of drug administration error during anaesthesia. Anaesth Intensive Care 2001; 29: 494-500.PubMed
2.
go back to reference Bowdle TA. Drug administration error from the ASA Closed Claims Project. ASA Newsletter 2003; 67: 11-3. Bowdle TA. Drug administration error from the ASA Closed Claims Project. ASA Newsletter 2003; 67: 11-3.
3.
go back to reference Llewellyn RL, Gordon PC, Wheatcroft D, et al. Drug administration errors: a prospective survey from three South African teaching hospitals. Anaesth Intensive Care 2009; 37: 93-8.PubMed Llewellyn RL, Gordon PC, Wheatcroft D, et al. Drug administration errors: a prospective survey from three South African teaching hospitals. Anaesth Intensive Care 2009; 37: 93-8.PubMed
4.
go back to reference Yamamoto M, Ishikawa S, Makita K. Medication errors in anesthesia: an 8-year retrospective analysis at an urban university hospital. J Anesth 2008; 22: 248-52.PubMedCrossRef Yamamoto M, Ishikawa S, Makita K. Medication errors in anesthesia: an 8-year retrospective analysis at an urban university hospital. J Anesth 2008; 22: 248-52.PubMedCrossRef
5.
go back to reference Fasting S, Gisvold SE. Adverse drug errors in anesthesia, and the impact of coloured syringe labels. Can J Anesth 2000; 47: 1060-7.PubMedCrossRef Fasting S, Gisvold SE. Adverse drug errors in anesthesia, and the impact of coloured syringe labels. Can J Anesth 2000; 47: 1060-7.PubMedCrossRef
6.
go back to reference Michaels AD, Spinler SA, Leeper B, et al. Medication errors in acute cardiovascular and stroke patients: a scientific statement from the American Heart Association. Circulation 2010; 121: 1664-82.PubMedCrossRef Michaels AD, Spinler SA, Leeper B, et al. Medication errors in acute cardiovascular and stroke patients: a scientific statement from the American Heart Association. Circulation 2010; 121: 1664-82.PubMedCrossRef
7.
go back to reference Abeysekera A, Bergman IJ, Kluger MT, Short TG. Drug error in anaesthetic practice: a review of 896 reports from the Australian Incident Monitoring Study database. Anaesthesia 2005; 60: 220-7.PubMedCrossRef Abeysekera A, Bergman IJ, Kluger MT, Short TG. Drug error in anaesthetic practice: a review of 896 reports from the Australian Incident Monitoring Study database. Anaesthesia 2005; 60: 220-7.PubMedCrossRef
8.
go back to reference Sakaguchi Y, Tokuda K, Yamaguchi K, Irita K. Incidence of anesthesia-related medication errors over a 15-year period in a university hospital. Fukuoka Igaku Zasshi 2008; 99: 58-66.PubMed Sakaguchi Y, Tokuda K, Yamaguchi K, Irita K. Incidence of anesthesia-related medication errors over a 15-year period in a university hospital. Fukuoka Igaku Zasshi 2008; 99: 58-66.PubMed
9.
go back to reference Kahn FA, Hoda MQ. A prospective survey of intra-operative critical incidents in a teaching hospital in a developing country. Anaesthesia 2001; 56: 177-82.CrossRef Kahn FA, Hoda MQ. A prospective survey of intra-operative critical incidents in a teaching hospital in a developing country. Anaesthesia 2001; 56: 177-82.CrossRef
10.
11.
go back to reference Wolf ZR, Hughes RG. Error reporting and disclosure. In: Hughes RG, editor. Patient Safety and Quality: An Evidence-Based Handbook for Nurses. Rockville, MD: Agency for Healthcare Research and Quality (US); 2008 . Wolf ZR, Hughes RG. Error reporting and disclosure. In: Hughes RG, editor. Patient Safety and Quality: An Evidence-Based Handbook for Nurses. Rockville, MD: Agency for Healthcare Research and Quality (US); 2008 .
12.
go back to reference Koczmara C, Dueck C, Jelincic V. To err is human, to share is divine. Dynamics 2006; 17: 22-5.PubMed Koczmara C, Dueck C, Jelincic V. To err is human, to share is divine. Dynamics 2006; 17: 22-5.PubMed
13.
go back to reference Engum SA, Breckler FD. An evaluation of medication errors-the pediatric surgical service experience. J Pediatr Surg 2008; 43: 348-52.PubMedCrossRef Engum SA, Breckler FD. An evaluation of medication errors-the pediatric surgical service experience. J Pediatr Surg 2008; 43: 348-52.PubMedCrossRef
14.
go back to reference Ghaleb MA, Barber N, Franklin BD, Yeung VW, Khaki ZF, Wong IC. Systematic review of medication errors in pediatric patients. Ann Pharmacother 2006; 40: 1766-76.PubMedCrossRef Ghaleb MA, Barber N, Franklin BD, Yeung VW, Khaki ZF, Wong IC. Systematic review of medication errors in pediatric patients. Ann Pharmacother 2006; 40: 1766-76.PubMedCrossRef
15.
go back to reference Meyer S. Grading of patients for surgical procedures. Anesthesiology 1941; 2: 281-4.CrossRef Meyer S. Grading of patients for surgical procedures. Anesthesiology 1941; 2: 281-4.CrossRef
16.
go back to reference Choy YC. Critical incident monitoring in anaesthesia. Med J Malaysia 2006; 61: 577-85.PubMed Choy YC. Critical incident monitoring in anaesthesia. Med J Malaysia 2006; 61: 577-85.PubMed
17.
go back to reference Rozich JD, Haraden CR, Resar RK. Adverse drug event trigger tool: a practical methodology for measuring medication related harm. Qual Saf Health Care 2003; 12: 194-200.PubMedCrossRef Rozich JD, Haraden CR, Resar RK. Adverse drug event trigger tool: a practical methodology for measuring medication related harm. Qual Saf Health Care 2003; 12: 194-200.PubMedCrossRef
18.
go back to reference Merry AF, Webster CS, Hannam J, et al. Multimodal system designed to reduce errors in recording and administration of drugs in anaesthesia: prospective randomised clinical evaluation. BMJ 2011; 343: d5543.PubMedCrossRef Merry AF, Webster CS, Hannam J, et al. Multimodal system designed to reduce errors in recording and administration of drugs in anaesthesia: prospective randomised clinical evaluation. BMJ 2011; 343: d5543.PubMedCrossRef
19.
go back to reference Cullen DJ, Bates DW, Adverse Drug Event Prevention Study Group. Prevention of adverse drug events: a decade of progress in patient safety. J Clin Anesth 2000; 12: 600-14.PubMedCrossRef Cullen DJ, Bates DW, Adverse Drug Event Prevention Study Group. Prevention of adverse drug events: a decade of progress in patient safety. J Clin Anesth 2000; 12: 600-14.PubMedCrossRef
21.
go back to reference Orser BA, Byrick R. Anesthesia-related medication error: time to take action. Can J Anesth 2004; 51: 756-60.PubMedCrossRef Orser BA, Byrick R. Anesthesia-related medication error: time to take action. Can J Anesth 2004; 51: 756-60.PubMedCrossRef
22.
go back to reference Ishikawa S, Murai K, Yokoyama K, Masuda A, Nakazawa K, Makita K. Retrospective analysis on misapplication of anesthesia-related drugs in the early stage of anesthesia training. J Anesth 2006; 20(Suppl): 265. Ishikawa S, Murai K, Yokoyama K, Masuda A, Nakazawa K, Makita K. Retrospective analysis on misapplication of anesthesia-related drugs in the early stage of anesthesia training. J Anesth 2006; 20(Suppl): 265.
23.
go back to reference Merry AF, Peck DJ. Anaesthetists, errors in drug administration and the law. N Z Med J 1995; 24: 185-7. Merry AF, Peck DJ. Anaesthetists, errors in drug administration and the law. N Z Med J 1995; 24: 185-7.
24.
go back to reference Wheeler SJ, Wheeler DW. Medication errors in anaesthesia and critical care. Anaesthesia 2005; 60: 257-73.PubMedCrossRef Wheeler SJ, Wheeler DW. Medication errors in anaesthesia and critical care. Anaesthesia 2005; 60: 257-73.PubMedCrossRef
25.
go back to reference Jensen LS, Merry AF, Webster CS, Weller J, Larsson L. Evidence-based strategies for preventing drug administration errors during anaesthesia. Anaesthesia 2004; 59: 493-504.PubMedCrossRef Jensen LS, Merry AF, Webster CS, Weller J, Larsson L. Evidence-based strategies for preventing drug administration errors during anaesthesia. Anaesthesia 2004; 59: 493-504.PubMedCrossRef
Metadata
Title
Influences observed on incidence and reporting of medication errors in anesthesia
Authors
Lebron Cooper, MD
Neil DiGiovanni, MD
Lucy Schultz, RN
Ashley M. Taylor, PharmD
Bobby Nossaman, MD
Publication date
01-06-2012
Publisher
Springer-Verlag
Published in
Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Issue 6/2012
Print ISSN: 0832-610X
Electronic ISSN: 1496-8975
DOI
https://doi.org/10.1007/s12630-012-9696-6

Other articles of this Issue 6/2012

Canadian Journal of Anesthesia/Journal canadien d'anesthésie 6/2012 Go to the issue

Book and New Media Reviews

Textbook of Critical Care, 6th Edition