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Current Breast Cancer Reports

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Open Access 01-06-2018 | Translational Research (RL Aft, Section Editor)

Immunotherapy in Breast Cancer: the New Frontier

Authors: Zishuo I. Hu, Heather L. McArthur

Published in: Current Breast Cancer Reports | Issue 2/2018

Abstract

Purpose of review

This review summarizes current immunotherapies in breast cancer, with an emphasis on immune checkpoint inhibitors and vaccines.

Recent findings

Combination immunotherapy with checkpoint inhibitors and cytotoxic therapies have shown promising results. Active clinical trials are ongoing in both early stage and metastatic settings for triple negative, HER2+, and hormone-positive breast cancer patients.

Summary

Ongoing challenges remain in defining biomarkers that predict response to immunotherapy, determining the optimal combination immunotherapies, and enhancing the immunogenicity of breast cancer subtypes.

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Title: Immunotherapy in Breast Cancer: the New Frontier
Authors: Zishuo I. Hu
Heather L. McArthur
Publication date: 01-06-2018
Publisher: Springer US
Published in: Current Breast Cancer Reports / Issue 2/2018
Print ISSN: 1943-4588
Electronic ISSN: 1943-4596
DOI: https://doi.org/10.1007/s12609-018-0274-y

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Abstract

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