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Published in: European Orthopaedics and Traumatology 3/2014

01-09-2014 | Original Article

Anterior cruciate ligament reconstruction using hamstring autograft in over-40 patients. Does preoperative arthritic changes matter?

Authors: Yasser A. Radwan, Ali M. Reda Mansour, Ahmed Rizk, George Malak

Published in: European Orthopaedics and Traumatology | Issue 3/2014

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Abstract

Introduction

The purpose of this study was to assess the effect of osteoarthritis on the outcome of arthroscopic anterior cruciate ligament (ACL) reconstruction, and to assess the effect of the procedure on the progression of osteoarthritis.

Material and methods

Forty-two patients, age above 40, presenting by symptomatic instability secondary to rupture of the ACL were enrolled in a prospective cohort study. Cases were divided into two groups according to the absence of osteoarthritic changes (group I, 19 patients) or presence of osteoarthritic changes (group II, 23 patients) in preoperative radiographs. ACL anatomic single bundle reconstruction by the anteromedial portal technique using hamstring autograft fixed by biodegradable interference fit screws was done for all patients, and a fixed postoperative rehabilitation protocol was applied. Data were recorded and statistical analysis of the preoperative, 1 year follow up, and final follow up (average 41 months in group I and 42 months in group II) results of both groups was conducted.

Results

The average patient age at the time of operation was 44.5 years in group I versus 46.4 years in group II. The follow-up median pain scores, ROM, modified Lysholm scores were significantly better in group I compared to group II. On the contrary, the difference between preoperative and 1 year postoperative scores and the percentage of improvement of the modified Lysholm score were significantly higher in group II. Deterioration of the radiographic grade of osteoarthritis in the final follow-up was declared in 15.8 % of patients of group I and in 21.7 % of patients of group II (P = 0.71). Age, concomitant meniscus injury, and presence of preoperative arthritic changes, and cartilage defect had no statistically significantly effect on the success rate. Patients who had ACL reconstruction more than 2 years after injury and those with higher body mass index (BMI) had worse outcome than those who had earlier reconstruction and lower BMI.

Conclusion

Patients having preoperative mild to moderate arthritic changes will indeed benefit from ACL reconstruction at short term, although their overall functional outcome seemed to be inferior to the outcome of non-arthritic patients. However, osteoarthritic changes deteriorate over time in both groups especially when there is preoperative mild to moderate arthritic changes.
Literature
1.
go back to reference Ciccotti M, Lombardo S, Nonweiler B, Pink M, Lind J (1994) Positive pivot shift after ACL reconstruction predicts later osteoarthrosis: non-operative treatment of ruptures of the anterior cruciate ligament in middle-aged patients. Results after long-term follow-up. J Bone Joint Surg 76(A):1315–1321PubMed Ciccotti M, Lombardo S, Nonweiler B, Pink M, Lind J (1994) Positive pivot shift after ACL reconstruction predicts later osteoarthrosis: non-operative treatment of ruptures of the anterior cruciate ligament in middle-aged patients. Results after long-term follow-up. J Bone Joint Surg 76(A):1315–1321PubMed
2.
go back to reference Fitzgerald G, Axe M, Snyder-Mackler L (2000) A decision making scheme for returning patients to high-level activity with non-operative treatment after anterior cruciate ligament rupture. Knee Surg Sports Traumatol Arthrosc 8:76–82PubMedCrossRef Fitzgerald G, Axe M, Snyder-Mackler L (2000) A decision making scheme for returning patients to high-level activity with non-operative treatment after anterior cruciate ligament rupture. Knee Surg Sports Traumatol Arthrosc 8:76–82PubMedCrossRef
3.
go back to reference Noyes F, Barber-Westin S (1997) Anterior cruciate ligament reconstruction with autogenous patellar tendon graft in patients with articular cartilage damage. Am J Sports Med 25:626–634PubMedCrossRef Noyes F, Barber-Westin S (1997) Anterior cruciate ligament reconstruction with autogenous patellar tendon graft in patients with articular cartilage damage. Am J Sports Med 25:626–634PubMedCrossRef
4.
go back to reference Seng K, Appleby D, Lubowitz J (2008) Operative versus non-operative treatment of anterior cruciate ligament rupture in patients aged 40 years or older: an expected-value decision analysis. Arthroscopy 24:914–920PubMedCrossRef Seng K, Appleby D, Lubowitz J (2008) Operative versus non-operative treatment of anterior cruciate ligament rupture in patients aged 40 years or older: an expected-value decision analysis. Arthroscopy 24:914–920PubMedCrossRef
5.
go back to reference Shelbourne K, Wilckens J (1993) Intra-articular anterior cruciate ligament reconstruction in the symptomatic arthritic knee. Am J Sports Med 21:685–689PubMedCrossRef Shelbourne K, Wilckens J (1993) Intra-articular anterior cruciate ligament reconstruction in the symptomatic arthritic knee. Am J Sports Med 21:685–689PubMedCrossRef
6.
go back to reference Strehl A, Eggli S (2007) The value of conservative treatment in ruptures of the anterior cruciate ligament (ACL). J Trauma 62:1159–1162PubMedCrossRef Strehl A, Eggli S (2007) The value of conservative treatment in ruptures of the anterior cruciate ligament (ACL). J Trauma 62:1159–1162PubMedCrossRef
7.
go back to reference Zysk S, Refior H (2000) Operative or conservative treatment of the acutely torn anterior cruciate ligament in middle-aged patients. A follow-up study of 133 patients between the ages of 40 and 59 years. Arch Orthop Trauma Surg 120:59–64PubMed Zysk S, Refior H (2000) Operative or conservative treatment of the acutely torn anterior cruciate ligament in middle-aged patients. A follow-up study of 133 patients between the ages of 40 and 59 years. Arch Orthop Trauma Surg 120:59–64PubMed
8.
go back to reference Ichiba A, Kishimoto I (2009) Effects of articular cartilage and meniscus injuries at the time of surgery on osteoarthritic changes after anterior cruciate ligament reconstruction in patients under 40 years old. Arch Orthop Trauma Surg 129:409–415PubMedCrossRef Ichiba A, Kishimoto I (2009) Effects of articular cartilage and meniscus injuries at the time of surgery on osteoarthritic changes after anterior cruciate ligament reconstruction in patients under 40 years old. Arch Orthop Trauma Surg 129:409–415PubMedCrossRef
9.
go back to reference Arbuthnot J, Brink R (2010) The role of anterior cruciate ligament reconstruction in the older patients, 55 years or above. Knee Surg Sports Traumatol Arthrosc 18:73–78PubMedCrossRef Arbuthnot J, Brink R (2010) The role of anterior cruciate ligament reconstruction in the older patients, 55 years or above. Knee Surg Sports Traumatol Arthrosc 18:73–78PubMedCrossRef
10.
go back to reference Barber F, Aziz-Jacobo J, Oro F (2010) Anterior cruciate ligament reconstruction using patellar tendon allograft: an age-dependent outcome evaluation. Arthroscopy 26:488–493PubMedCrossRef Barber F, Aziz-Jacobo J, Oro F (2010) Anterior cruciate ligament reconstruction using patellar tendon allograft: an age-dependent outcome evaluation. Arthroscopy 26:488–493PubMedCrossRef
11.
go back to reference Barrett G, Stokes D, White M (2005) Anterior cruciate ligament reconstruction in patients older than 40 years: allograft versus autograft patellar tendon. Am J Sports Med 33:1505–1512PubMedCrossRef Barrett G, Stokes D, White M (2005) Anterior cruciate ligament reconstruction in patients older than 40 years: allograft versus autograft patellar tendon. Am J Sports Med 33:1505–1512PubMedCrossRef
12.
go back to reference Blyth M, Gosal H, Peake W, Bartlett R (2003) Anterior cruciate ligament reconstruction in patients over the age of 50 years: 2- to 8-year follow-up. Knee Surg Sports Traumatol Arthrosc 11:204–211PubMedCrossRef Blyth M, Gosal H, Peake W, Bartlett R (2003) Anterior cruciate ligament reconstruction in patients over the age of 50 years: 2- to 8-year follow-up. Knee Surg Sports Traumatol Arthrosc 11:204–211PubMedCrossRef
13.
go back to reference Brandsson S, Kartus J, Larsson J, Eriksson B, Karlsson J (2000) A comparison of results in middle-aged and young patients after anterior cruciate ligament reconstruction. Arthroscopy 16:178–182PubMedCrossRef Brandsson S, Kartus J, Larsson J, Eriksson B, Karlsson J (2000) A comparison of results in middle-aged and young patients after anterior cruciate ligament reconstruction. Arthroscopy 16:178–182PubMedCrossRef
14.
go back to reference Dahm D, Wulf C, Dajani K, Dobbs R, Levy B, Stuart M (2008) Reconstruction of the anterior cruciate ligament in patients over 50 years. J Bone Joint Surg Br 90:1446–1450PubMedCrossRef Dahm D, Wulf C, Dajani K, Dobbs R, Levy B, Stuart M (2008) Reconstruction of the anterior cruciate ligament in patients over 50 years. J Bone Joint Surg Br 90:1446–1450PubMedCrossRef
15.
go back to reference Deehan D, Salmon J, Webb V, Davies A, Pinczewski L (2000) Endoscopic reconstruction of the anterior cruciate ligament with an ipsilateral patellar tendon autograft. A prospective longitudinal 5-years study. J Bone Joint Surg 82(B):984–991CrossRef Deehan D, Salmon J, Webb V, Davies A, Pinczewski L (2000) Endoscopic reconstruction of the anterior cruciate ligament with an ipsilateral patellar tendon autograft. A prospective longitudinal 5-years study. J Bone Joint Surg 82(B):984–991CrossRef
16.
go back to reference Javernick M, Potter B, Mack A, Dekay K, Murphy K (2006) Autologous hamstring anterior cruciate ligament reconstruction in patients older than 40. Am J Orthop 35:430–434PubMed Javernick M, Potter B, Mack A, Dekay K, Murphy K (2006) Autologous hamstring anterior cruciate ligament reconstruction in patients older than 40. Am J Orthop 35:430–434PubMed
17.
go back to reference Jomha N, Borton D, Clingeleffer A, Pinczewski L (1999) Long-term osteoarthritic changes in anterior cruciate reconstructed knees. Clin Orthop 358:188–193PubMedCrossRef Jomha N, Borton D, Clingeleffer A, Pinczewski L (1999) Long-term osteoarthritic changes in anterior cruciate reconstructed knees. Clin Orthop 358:188–193PubMedCrossRef
18.
go back to reference Khan R, Prasad V, Gangone R (2010) Anterior cruciate ligament reconstruction in patients over 40 years using hamstring autografts. Knee Surg Sports Traumatol Arthrosc 18:68–72PubMedCrossRef Khan R, Prasad V, Gangone R (2010) Anterior cruciate ligament reconstruction in patients over 40 years using hamstring autografts. Knee Surg Sports Traumatol Arthrosc 18:68–72PubMedCrossRef
19.
go back to reference Kuechle D, Pearson S, Beach W, Freeman E, Pawlowski D, Whipple T, Caspari R, Meyers J (2002) Allograft anterior cruciate ligament reconstruction in patients over 40 years of age. Arthroscopy 18:845–853PubMedCrossRef Kuechle D, Pearson S, Beach W, Freeman E, Pawlowski D, Whipple T, Caspari R, Meyers J (2002) Allograft anterior cruciate ligament reconstruction in patients over 40 years of age. Arthroscopy 18:845–853PubMedCrossRef
20.
go back to reference Marquass B, Hepp P, Engel T, Dusing T, Lill H, Josten C (2007) The use of hamstrings in anterior cruciate ligament reconstruction in patients over 40 years. Arch Orthop Trauma Surg 127:835–843PubMedCrossRef Marquass B, Hepp P, Engel T, Dusing T, Lill H, Josten C (2007) The use of hamstrings in anterior cruciate ligament reconstruction in patients over 40 years. Arch Orthop Trauma Surg 127:835–843PubMedCrossRef
21.
go back to reference Mihelic R, Jurdana H, Jotanovic Z, Madjarevic T, Tudor A (2011) Long-term results of anterior cruciate reconstruction: a comparison with non-operative treatment with a follow-up of 17–20 years. Int Orthop 35(7):1093–1097PubMedCentralPubMedCrossRef Mihelic R, Jurdana H, Jotanovic Z, Madjarevic T, Tudor A (2011) Long-term results of anterior cruciate reconstruction: a comparison with non-operative treatment with a follow-up of 17–20 years. Int Orthop 35(7):1093–1097PubMedCentralPubMedCrossRef
22.
go back to reference Osti L, Papalia R, Del Buono A, Leonardi F, Denaro V, Maffulli N (2011) Surgery for ACL deficiency in patients over 50. Knee Surg Sports Traumatol Arthrosc 19:412–417PubMedCrossRef Osti L, Papalia R, Del Buono A, Leonardi F, Denaro V, Maffulli N (2011) Surgery for ACL deficiency in patients over 50. Knee Surg Sports Traumatol Arthrosc 19:412–417PubMedCrossRef
23.
go back to reference Stein D, Brown H, Bartolozzi A (2006) Age and ACL reconstruction revisited. Orthopedics 29:533–536PubMed Stein D, Brown H, Bartolozzi A (2006) Age and ACL reconstruction revisited. Orthopedics 29:533–536PubMed
24.
go back to reference Viola R, Vianello R (1999) Intra-articular ACL reconstruction in the over-40-year-old patient. Knee Surg Sports Traumatol Arthrosc 7:25–28PubMedCrossRef Viola R, Vianello R (1999) Intra-articular ACL reconstruction in the over-40-year-old patient. Knee Surg Sports Traumatol Arthrosc 7:25–28PubMedCrossRef
25.
go back to reference Torg J, Conrad W, Kalen V (1976) Clinical diagnosis of anterior cruciate ligament instability in the athlete. Am J Sports Med 4:84–93PubMedCrossRef Torg J, Conrad W, Kalen V (1976) Clinical diagnosis of anterior cruciate ligament instability in the athlete. Am J Sports Med 4:84–93PubMedCrossRef
26.
go back to reference Fetto J, Marshall J (1979) Injury to the anterior cruciate ligament producing the pivot-shift sign. J Bone Joint Surg Am 61:710–714PubMed Fetto J, Marshall J (1979) Injury to the anterior cruciate ligament producing the pivot-shift sign. J Bone Joint Surg Am 61:710–714PubMed
27.
go back to reference Lane C, Warren R, Pearle A (2008) The pivot shift. J Am Acad Orthop Surg 16:679–688PubMed Lane C, Warren R, Pearle A (2008) The pivot shift. J Am Acad Orthop Surg 16:679–688PubMed
28.
go back to reference Lysholm J, Gillquist J (1982) Evaluation of knee ligament surgery results with special emphasis on use of a scoring scale. Am J Sports Med 10:150–154PubMedCrossRef Lysholm J, Gillquist J (1982) Evaluation of knee ligament surgery results with special emphasis on use of a scoring scale. Am J Sports Med 10:150–154PubMedCrossRef
29.
go back to reference Tegner Y, Lysholm J (1985) Rating systems in the evaluation of knee ligament injuries. Clin Orthop Relat Res 198:43–49PubMed Tegner Y, Lysholm J (1985) Rating systems in the evaluation of knee ligament injuries. Clin Orthop Relat Res 198:43–49PubMed
30.
go back to reference Hefti F, Muller W, Jakob R, Staubli H (1993) Evaluation of knee ligament injuries with the IKDC form. Knee Surg Sports Traumatol Arthrosc 1:226–234PubMedCrossRef Hefti F, Muller W, Jakob R, Staubli H (1993) Evaluation of knee ligament injuries with the IKDC form. Knee Surg Sports Traumatol Arthrosc 1:226–234PubMedCrossRef
31.
go back to reference Noyes F, Stabler C (1989) A system for grading articular cartilage lesions at arthroscopy. Am J Sports Med 17:505–513PubMedCrossRef Noyes F, Stabler C (1989) A system for grading articular cartilage lesions at arthroscopy. Am J Sports Med 17:505–513PubMedCrossRef
32.
go back to reference Steadman J, Briggs K, Rodrigo J, Kocher M, Gill T, Rodkey W (2003) Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-up. Arthroscopy 19:477–484PubMedCrossRef Steadman J, Briggs K, Rodrigo J, Kocher M, Gill T, Rodkey W (2003) Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-up. Arthroscopy 19:477–484PubMedCrossRef
33.
go back to reference Aït Si Selmi T, Fithian D, Neyret P (2006) The evolution of osteoarthritis in 103 patients with ACL reconstruction at 17 years follow-up. Knee 13:353–358PubMedCrossRef Aït Si Selmi T, Fithian D, Neyret P (2006) The evolution of osteoarthritis in 103 patients with ACL reconstruction at 17 years follow-up. Knee 13:353–358PubMedCrossRef
34.
go back to reference Daniel D, Stone M, Dobson B, Fithian D, Rossman D, Kaufman K (1994) Fate of the ACL-injured patient. A prospective outcome study. Am J Sports Med 22:632–644PubMedCrossRef Daniel D, Stone M, Dobson B, Fithian D, Rossman D, Kaufman K (1994) Fate of the ACL-injured patient. A prospective outcome study. Am J Sports Med 22:632–644PubMedCrossRef
35.
go back to reference Joseph C, Pathak S, Aravinda M, Rajan D (2008) Is ACL reconstruction only for athletes? A study of the incidence of meniscal and cartilage injuries in an ACL-deficient athlete and non-athlete population: an Indian experience. Int Orthop 32:57–61PubMedCentralPubMedCrossRef Joseph C, Pathak S, Aravinda M, Rajan D (2008) Is ACL reconstruction only for athletes? A study of the incidence of meniscal and cartilage injuries in an ACL-deficient athlete and non-athlete population: an Indian experience. Int Orthop 32:57–61PubMedCentralPubMedCrossRef
36.
go back to reference Lidén M, Sernert N, Rostgard-Christensen L, Kartus C, Ejerhed L (2008) Osteoarthritic changes after anterior cruciate ligament reconstruction using bone–patellar tendon–bone or hamstring tendon autografts: a retrospective, 7-year radiographic and clinical follow-up study. Arthroscopy 24:899–908PubMedCrossRef Lidén M, Sernert N, Rostgard-Christensen L, Kartus C, Ejerhed L (2008) Osteoarthritic changes after anterior cruciate ligament reconstruction using bone–patellar tendon–bone or hamstring tendon autografts: a retrospective, 7-year radiographic and clinical follow-up study. Arthroscopy 24:899–908PubMedCrossRef
37.
go back to reference Papastergiou S, Koukoulias N, Mikalef P, Ziogas E, Voulgaropoulos H (2007) Meniscal tears in the ACL-deficient knee: correlation between meniscal tears and the timing of ACL reconstruction. Knee Surg Sports Traumatol Arthrosc 15:1438–1444PubMedCrossRef Papastergiou S, Koukoulias N, Mikalef P, Ziogas E, Voulgaropoulos H (2007) Meniscal tears in the ACL-deficient knee: correlation between meniscal tears and the timing of ACL reconstruction. Knee Surg Sports Traumatol Arthrosc 15:1438–1444PubMedCrossRef
Metadata
Title
Anterior cruciate ligament reconstruction using hamstring autograft in over-40 patients. Does preoperative arthritic changes matter?
Authors
Yasser A. Radwan
Ali M. Reda Mansour
Ahmed Rizk
George Malak
Publication date
01-09-2014
Publisher
Springer Berlin Heidelberg
Published in
European Orthopaedics and Traumatology / Issue 3/2014
Print ISSN: 1867-4569
Electronic ISSN: 1867-4577
DOI
https://doi.org/10.1007/s12570-013-0243-x

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