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International Journal of Behavioral Medicine

Published in:

01-06-2009

Depressive Symptoms and Cervical Neoplasia in HIV+ Low-Income Minority Women with Human Papillomavirus Infection

Authors: Stacy M. Dodd, Deidre B. Pereira, Ilona Marion, Michele Andrasik, Rachel Rose, Trudi Simon, Mary Ann Fletcher, Joseph Lucci, Kevin Maher, Mary Jo O’Sullivan, JoNell Efantis-Potter, Michael H. Antoni

Published in: International Journal of Behavioral Medicine | Issue 2/2009

Abstract

Background

Prior work has related elevated life stress to greater risk of cervical neoplasia in women with human immunodeficiency virus (HIV) and human papillomavirus (HPV).

Purpose

This study investigated associations between depressive symptoms and cervical neoplasia in HIV+ HPV+ women. Participants were 58 HIV+ HPV+ women.

Method

Participants underwent colposcopy, including HPV screening, Papanicolaou smear, and cervical biopsy to determine study eligibility. Eligible participants completed the Beck Depression Inventory (BDI) and the Center for Epidemiologic Studies-Depression (CES-D) scale.

Results

Presence and severity of clinically significant depressive symptomatology were associated with cervical neoplasia. Hierarchical logistic regression analysis revealed that women with greater depressive symptoms had marginally greater odds of presenting with cervical neoplasia (BDI: OR = 1.16, p = 0.092; CES-D: OR = 1.15, p = 0.067. Women with greater somatic depressive symptoms, specifically, had significantly greater odds of presenting with cervical neoplasia (BDI: OR = 1.86, p = 0.027; CES-D: OR = 1.56, p = 0.017).

Conclusion

These findings suggest that screening HIV+ women for somatic depression may help identify those at risk for cervical neoplasia. Future depression research with medical populations should discern somatic depressive symptoms from disease symptoms, as they may have important value in independently predicting health outcomes.

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Title: Depressive Symptoms and Cervical Neoplasia in HIV+ Low-Income Minority Women with Human Papillomavirus Infection
Authors: Stacy M. Dodd
Deidre B. Pereira
Ilona Marion
Michele Andrasik
Rachel Rose
Trudi Simon
Mary Ann Fletcher
Joseph Lucci
Kevin Maher
Mary Jo O’Sullivan
JoNell Efantis-Potter
Michael H. Antoni
Publication date: 01-06-2009
Publisher: Springer US
Published in: International Journal of Behavioral Medicine / Issue 2/2009
Print ISSN: 1070-5503
Electronic ISSN: 1532-7558
DOI: https://doi.org/10.1007/s12529-008-9025-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Depressive Symptoms and Cervical Neoplasia in HIV+ Low-Income Minority Women with Human Papillomavirus Infection

Abstract

Background

Purpose

Method

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Purpose

Method

Results

Conclusion

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