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World Journal of Pediatrics
Published in: World Journal of Pediatrics 5/2018

01-10-2018 | Original Article

Determinants for asthma control, quality of life and use of complementary and alternative medicine in asthmatic pediatric patients in four cities

Authors: Kam Lun Hon, Yan Min Bao, Kate C. Chan, Kin Wai Chau, Rong-Shan Chen, Kun Tat Gary Cheok, Wa Keung Chiu, Li Deng, Chun-Hui He, Kin Mui Ieong, Jeng Sum C. Kung, Ping Lam, Shu Yan David Lam, Qun Ui Lee, So Lun Lee, Ting Fan Leung, Theresa N. H. Leung, Lei Shi, Ka Ka Siu, Wei-Ping Tan, Maggie Haitian Wang, Tak Wai Wong, Bao-Jing Wu, Ada Y. F. Yip, Yue-Jie Zheng, Daniel K. Ng

Published in: World Journal of Pediatrics | Issue 5/2018

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Abstract

Background

Asthma is a significant chronic health problem worldwide. Management aims at disease control by reducing functional impairment and exacerbations and improving quality of life (QoL). We report a multi-center study to survey asthma control and QoL in four cities in the Pearl River Delta.

Methods

The conjoint survey involved ten Hong Kong pediatric hospitals/units, two Shenzhen hospitals, two Macau hospitals, and two Guangzhou hospitals on asthma control (using Asthma Control Test) and QoL (Pediatric Allergic Disease Quality of Life Questionnaire, PADQLQ). Acceptability of a treatment is graded as very good/good/fair/poor.

Results

Good asthma control was only reported in 80% subjects in Hong Kong, but higher in sister cities (85–94%, P < 0.001). Allergic rhinitis, “incense burning”, and “smoker in family” were prevalent among the four cities. Logistic regression showed better control of asthma was associated with better PADQLQ (B = − 0.029, P < 0.001), better acceptability of bronchodilator (B = − 1.488, P = 0.025), negatively with “smoker in family” (B = − 0.83, P = 0.015) and various PADQLQ domains. Conversely, worse PADQLQ was associated with allergic rhinitis severity (B = 4.77, P < 0.001), poor control of asthma (B = 7.56, P < 0.001), increased frequency of traditional Chinese medicine use (B = 1.7, P < 0.05), increased frequency of bronchodilator usage (B = 1.05, P < 0.05), “smoker in family” (B = 4.05, P < 0.05), and incense burning at home (B = 3.9, P < 0.05).

Conclusions

There are some clinical and cultural differences among the four southern Chinese cities within the Guangdong province. This study identifies potentially modifiable environmental and treatment factors associated with poor asthma control and QoL for health-care interventions. Having a smoker in the family is independently associated with poor asthma control and QoL.
Appendix
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Metadata
Title
Determinants for asthma control, quality of life and use of complementary and alternative medicine in asthmatic pediatric patients in four cities
Authors
Kam Lun Hon
Yan Min Bao
Kate C. Chan
Kin Wai Chau
Rong-Shan Chen
Kun Tat Gary Cheok
Wa Keung Chiu
Li Deng
Chun-Hui He
Kin Mui Ieong
Jeng Sum C. Kung
Ping Lam
Shu Yan David Lam
Qun Ui Lee
So Lun Lee
Ting Fan Leung
Theresa N. H. Leung
Lei Shi
Ka Ka Siu
Wei-Ping Tan
Maggie Haitian Wang
Tak Wai Wong
Bao-Jing Wu
Ada Y. F. Yip
Yue-Jie Zheng
Daniel K. Ng
Publication date
01-10-2018
Publisher
Childrens Hospital, Zhejiang University School of Medicine
Published in
World Journal of Pediatrics / Issue 5/2018
Print ISSN: 1708-8569
Electronic ISSN: 1867-0687
DOI
https://doi.org/10.1007/s12519-018-0167-1

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