Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Journal of Ophthalmic Inflammation and Infection
Published in: Journal of Ophthalmic Inflammation and Infection 4/2011

Open Access 01-12-2011 | Original Research

Trabeculectomy or modified deep sclerectomy in juvenile uveitic glaucoma

Authors: Carsten Heinz, Jörg M. Koch, Arnd Heiligenhaus

Published in: Journal of Ophthalmic Inflammation and Infection | Issue 4/2011

Login to get access

Abstract

Purpose

The purpose of this study is to report the effectiveness of trabeculectomies (TE) and modified deep sclerectomies (mdS) in a group of patients with juvenile uveitic secondary glaucoma.

Methods

This is a retrospective analysis of 16 TE and eight mdS.

Results

Postoperatively, an IOP reduction to 11.6 ± 4.7 mmHg was achieved in the TE group and to 18.5 ± 11.4 mmHg in the mdS group (p = 0.045). In the TE group, 14 patients showed postoperative success, one limited success and another was a failure compared to four successes and four failures in the mdS group (p = 0.041). The mean number of complications was 1.25 ± 1.49 in the TE group and 0.38 ± 0.74 after mdS (p = 0.11). In the mdS group, four patients (50%) needed additional glaucoma surgery compared to one TE patient (p = 0.023).

Conclusion

Both surgical techniques showed a marked reduction of IOP. Trabeculectomy has a higher probability of achieving success and lowering IOP.
Literature
1.
Heiligenhaus A, Niewerth M, Ganser G, Heinz C, Minden K (2007) Prevalence and complications of uveitis in juvenile idiopathic arthritis in a population-based nation-wide study in Germany: suggested modification of the current screening guidelines. Rheumatology (Oxford) 46(6):1015–1019CrossRef
2.
Heiligenhaus A, Niewerth M, Mingels A, Ganser G, Thon A, Pleyer U, Greiner K, Minden K (2005) Epidemiology of uveitis in juvenile idiopathic arthritis from a national paediatric rheumatologic and ophthalmologic database. Klin Monbl Augenheilkd 222(12):993–1001PubMedCrossRef
3.
Mingels A, Hudde T, Heinz C, Heiligenhaus A (2005) Visusmindernde Komplikationen bei Uveitis im Kindesalter. Ophthalmologe 102(5):477–484PubMedCrossRef
4.
Sijssens KM, Rothova A, Berendschot TT, de Boer JH (2006) Ocular hypertension and secondary glaucoma in children with uveitis. Ophthalmology 113(5):859CrossRef
5.
Foster CS, Havrlikova K, Baltatzis S, Christen WG, Merayo-Lloves J (2000) Secondary glaucoma in patients with juvenile rheumatoid arthritis-associated iridocyclitis. Acta Ophthalmol Scand 78(5):576–579PubMedCrossRef
6.
Heinz C, Koch JM, Zurek-Imhoff B, Heiligenhaus A (2009) Prevalence of uveitic secondary glaucoma and success of nonsurgical treatment in adults and children in a tertiary referral center. Ocul Immunol Inflamm 17(4):243–248PubMedCrossRef
7.
Jabs DA, Nussenblatt RB, Rosenbaum JT (2005) Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol 140(3):509–516PubMedCrossRef
8.
Bloch-Michel E, Nussenblatt RB (1987) International Uveitis Study Group recommendations for the evaluation of intraocular inflammatory disease. Am J Ophthalmol 103(2):234–235PubMedCrossRef
9.
Broadway DC, Grierson I, Sturmer J, Hitchings RA (1996) Reversal of topical antiglaucoma medication effects on the conjunctiva. Arch Ophthalmol 114(3):262–267PubMedCrossRef
10.
Shaarawy TM, Sherwood MB, Grehn F (eds) (2009) Guidelines on design and reporting of glaucoma surgical trials. Kugler, Amsterdam
11.
Ho CL, Wong EY, Walton DS (2004) Goniosurgery for glaucoma complicating chronic childhood uveitis. Arch Ophthalmol 122(6):838–844PubMedCrossRef
12.
Kafkala C, Hynes A, Choi J, Topalkara A, Foster CS (2005) Ahmed valve implantation for uncontrolled pediatric uveitic glaucoma. J AAPOS 9(4):336–340PubMedCrossRef
13.
Kanski JJ, McAllister JA (1985) Trabeculodialysis for inflammatory glaucoma in children and young adults. Ophthalmology 92(7):927–930PubMedCrossRef
14.
Valimaki J, Airaksinen PJ, Tuulonen A (1997) Molteno implantation for secondary glaucoma in juvenile rheumatoid arthritis. Arch Ophthalmol 115(10):1253–1256PubMedCrossRef
15.
Heinz C, Koch JM, Heiligenhaus A (2006) Transscleral diode laser cyclophotocoagulation as primary surgical treatment for secondary glaucoma in juvenile idiopathic arthritis: high failure rate after short term follow up. Br J Ophthalmol 90(6):737–740PubMedPubMedCentralCrossRef
16.
Arruabarrena C, Munoz-Negrete FJ, Marquez C, Rebolleda G (2007) Results of nonpenetrating deep sclerectomy in inflammatory glaucoma: one year follow up. Arch Soc Esp Oftalmol 82(8):483–487PubMedCrossRef
17.
Auer C, Mermoud A, Herbort CP (2004) Deep sclerectomy for the management of uncontrolled uveitic glaucoma: preliminary data. Klin Monbl Augenheilkd 221(5):339–342PubMedCrossRef
18.
Souissi K, El Afrit MA, Trojet S, Kraiem A (2006) Deep sclerectomy for the management of uveitic glaucoma. J Fr Ophtalmol 29(3):265–268PubMedCrossRef
19.
Moreno-Montanes J, Rebolleda G, Munoz-Negrete FJ (2007) Prognostic value of gonioscopy after deep sclerectomy. Eur J Ophthalmol 17(5):702–708PubMed
20.
Souissi K, El Afrit MA, Trojet S, Kraiem A (2006) Trabeculectomy for the management of uveitic glaucoma. J Fr Ophtalmol 29(2):153–156PubMedCrossRef
21.
Beck AD, Wilson WR, Lynch MG, Lynn MJ, Noe R (1998) Trabeculectomy with adjunctive mitomycin C in pediatric glaucoma. Am J Ophthalmol 126(5):648–657PubMedCrossRef
22.
Cillino S, Di Pace F, Casuccio A, Lodato G (2005) Deep sclerectomy versus punch trabeculectomy: effect of low-dosage mitomycin C. Ophthalmologica 219(5):281–286PubMedCrossRef
23.
Cillino S, Di Pace F, Casuccio A, Calvaruso L, Morreale D, Vadala M, Lodato G (2004) Deep sclerectomy versus punch trabeculectomy with or without phacoemulsification: a randomized clinical trial. J Glaucoma 13(6):500–506PubMedCrossRef
Metadata
Title
Trabeculectomy or modified deep sclerectomy in juvenile uveitic glaucoma
Authors
Carsten Heinz
Jörg M. Koch
Arnd Heiligenhaus
Publication date
01-12-2011
Publisher
Springer Berlin Heidelberg
Published in
Journal of Ophthalmic Inflammation and Infection / Issue 4/2011
Electronic ISSN: 1869-5760
DOI
https://doi.org/10.1007/s12348-011-0039-5

Other articles of this Issue 4/2011

Journal of Ophthalmic Inflammation and Infection 4/2011 Go to the issue

Brief Report

Rituximab in refractory Vogt–Koyanagi–Harada disease

Photo Assay

Subretinal pigment epithelial infiltrates in primary vitreoretinal lymphoma

Original Research

Phase II placebo-controlled study of nepafenac ophthalmic suspension 0.1% for postoperative inflammation and ocular pain associated with cataract surgery in Japanese patients

Original Research

High-resolution spectral domain optical coherence tomography and fundus autofluorescence correlation in tubercular serpiginouslike choroiditis

Brief Report

Kyrieleis plaques in cytomegalovirus retinitis

Brief Report

Refractive changes in patients with autoimmune scleritis