Skip to main content
Top
Published in: MUSCULOSKELETAL SURGERY 1/2013

01-04-2013 | Case Report

Propionibacterium acnes delayed infection following spinal surgery with instrumentation

Authors: Hani H. Mhaidli, Asdghig H. Der-Boghossian, Rachid K. Haidar

Published in: MUSCULOSKELETAL SURGERY | Issue 1/2013

Login to get access

Abstract

Propionibacterium acnes detection in culture media was previously considered a contamination but recently its infectious role was discovered in post-spinal surgery infections. P. acnes might be introduced during surgery. Its diagnosis is based on non-specific clinical signs, image indications of infection, and the conclusive microbiological sign. Furthermore, its diagnosis is difficult because of slow growth rate and low virulence, delaying its presentation. Usually, the infection is manifested after a couple of months or years. Here, a 65-year-old man presented with drainage at the site of instrumented spinal surgery performed 13 years ago. P. acnes infection was confirmed by culture with extended incubation. Our review of the literature revealed only two other reported cases of delayed P. acnes infection presenting a decade following a spinal surgery with instrumentation. This article sheds light on such delayed infections and discusses their presentation and management.
Literature
1.
go back to reference Cogen AL, Nizet V, Gallo RL (2008) Skin microbiota: a source of disease or defense? Br J Dermatol 158:442–455PubMedCrossRef Cogen AL, Nizet V, Gallo RL (2008) Skin microbiota: a source of disease or defense? Br J Dermatol 158:442–455PubMedCrossRef
2.
go back to reference Nisbet M, Briggs S, Ellis-Pegler R, Thomas M, Holland D (2007) Propionibacterium acnes: an under-appreciated cause of post-neurosurgical infection. J Antimicrob Chemother 60:1097–1103PubMedCrossRef Nisbet M, Briggs S, Ellis-Pegler R, Thomas M, Holland D (2007) Propionibacterium acnes: an under-appreciated cause of post-neurosurgical infection. J Antimicrob Chemother 60:1097–1103PubMedCrossRef
3.
go back to reference Rihn JA, Lee JY, Ward WT (2008) Infection after the surgical treatment of adolescent idiopathic scoliosis: evaluation of the diagnosis, treatment, and impact on clinical outcomes. Spine (Phila Pa 1976) 33:289–294CrossRef Rihn JA, Lee JY, Ward WT (2008) Infection after the surgical treatment of adolescent idiopathic scoliosis: evaluation of the diagnosis, treatment, and impact on clinical outcomes. Spine (Phila Pa 1976) 33:289–294CrossRef
4.
go back to reference Trampuz A, Widmer AF (2006) Infections associated with orthopedic implants. Curr Opin Infect Dis 19:349–356PubMedCrossRef Trampuz A, Widmer AF (2006) Infections associated with orthopedic implants. Curr Opin Infect Dis 19:349–356PubMedCrossRef
5.
go back to reference Bémer P, Corvec S, Tariel S, Asseray N, Boutoille D, Langlois C et al (2008) Significance of Propionibacterium acnes-positive samples in spinal instrumentation. Spine (Phila Pa 1976) 33:E971–E976CrossRef Bémer P, Corvec S, Tariel S, Asseray N, Boutoille D, Langlois C et al (2008) Significance of Propionibacterium acnes-positive samples in spinal instrumentation. Spine (Phila Pa 1976) 33:E971–E976CrossRef
7.
go back to reference Jakab E, Zbinden R, Gubler J, Ruef C, Von Graevenitz A, Krause M (1996) Severe infections caused by Propionibacterium acnes: an underestimated pathogen in late postoperative infections. Yale J Biol Med 69:477–482PubMed Jakab E, Zbinden R, Gubler J, Ruef C, Von Graevenitz A, Krause M (1996) Severe infections caused by Propionibacterium acnes: an underestimated pathogen in late postoperative infections. Yale J Biol Med 69:477–482PubMed
8.
go back to reference Goldschmidt P, Ferreira CC, Degorge S, Benallaoua D, Boutboul S, Laroche L et al (2009) Rapid detection and quantification of Propionibacteriaceae. Br J Ophthalmol 93:258–262PubMedCrossRef Goldschmidt P, Ferreira CC, Degorge S, Benallaoua D, Boutboul S, Laroche L et al (2009) Rapid detection and quantification of Propionibacteriaceae. Br J Ophthalmol 93:258–262PubMedCrossRef
9.
go back to reference Haidar R, Najjar M, Der Boghossian A, Tabbarah Z (2010) Propionibacterium acnes causing delayed postoperative spine infection: review. Scand J Infect Dis 42:405–411PubMedCrossRef Haidar R, Najjar M, Der Boghossian A, Tabbarah Z (2010) Propionibacterium acnes causing delayed postoperative spine infection: review. Scand J Infect Dis 42:405–411PubMedCrossRef
10.
go back to reference Richards BS, Emara KM (2001) Delayed infections after posterior TSRH spinal instrumentation for idiopathic scoliosis: revisited. Spine (Phila Pa 1976) 26:1990–1996CrossRef Richards BS, Emara KM (2001) Delayed infections after posterior TSRH spinal instrumentation for idiopathic scoliosis: revisited. Spine (Phila Pa 1976) 26:1990–1996CrossRef
11.
go back to reference Richards BS, Herring JA, Johnston CE, Birch JG, Roach JW (1994) Treatment of adolescent idiopathic scoliosis using Texas Scottish Rite Hospital instrumentation. Spine (Phila Pa 1976) 19:1598–1605CrossRef Richards BS, Herring JA, Johnston CE, Birch JG, Roach JW (1994) Treatment of adolescent idiopathic scoliosis using Texas Scottish Rite Hospital instrumentation. Spine (Phila Pa 1976) 19:1598–1605CrossRef
12.
go back to reference Kourbetia IS, Tsiodrasb S, Boumpas DT (2008) Spinal infections: evolving concepts. Curr Opin Rheumatol 20:471–479CrossRef Kourbetia IS, Tsiodrasb S, Boumpas DT (2008) Spinal infections: evolving concepts. Curr Opin Rheumatol 20:471–479CrossRef
13.
go back to reference Bose B (2003) Delayed infection after instrumented spine surgery: case reports and review of the literature. Spine J 3:394–399PubMedCrossRef Bose B (2003) Delayed infection after instrumented spine surgery: case reports and review of the literature. Spine J 3:394–399PubMedCrossRef
14.
go back to reference Chaudhary SB, Vives MJ, Basra SK, Reiter MF (2007) Postoperative spinal wound infections and postprocedural diskitis. J Spinal Cord Med 30:441–451PubMed Chaudhary SB, Vives MJ, Basra SK, Reiter MF (2007) Postoperative spinal wound infections and postprocedural diskitis. J Spinal Cord Med 30:441–451PubMed
15.
go back to reference Collins I, Wilson-MacDonald J, Chami G, Burgoyne W, Vineyakam P, Berendt T et al (2008) The diagnosis and management of infection following instrumented spinal fusion. Eur Spine J 17:445–450PubMedCrossRef Collins I, Wilson-MacDonald J, Chami G, Burgoyne W, Vineyakam P, Berendt T et al (2008) The diagnosis and management of infection following instrumented spinal fusion. Eur Spine J 17:445–450PubMedCrossRef
16.
go back to reference Luzzati R, Giacomazzi D, Danzi MC, Tacconi L, Concia E, Vento S (2009) Diagnosis, management and outcome of clinically suspected spinal infection. J Infect 58:259–265PubMedCrossRef Luzzati R, Giacomazzi D, Danzi MC, Tacconi L, Concia E, Vento S (2009) Diagnosis, management and outcome of clinically suspected spinal infection. J Infect 58:259–265PubMedCrossRef
17.
go back to reference Balériaux DL, Neugroschl C (2004) Spinal and spinal cord infection. Eur Radiol 14:E72–E83PubMed Balériaux DL, Neugroschl C (2004) Spinal and spinal cord infection. Eur Radiol 14:E72–E83PubMed
18.
go back to reference Viraraghavan R, Jantausch B, Campos J (2004) Late-onset central nervous system shunt infections with Propionibacterium acnes: diagnosis and management. Clin Pediatr (Phila) 43:393–397CrossRef Viraraghavan R, Jantausch B, Campos J (2004) Late-onset central nervous system shunt infections with Propionibacterium acnes: diagnosis and management. Clin Pediatr (Phila) 43:393–397CrossRef
19.
go back to reference Tribus CB, Garvey KE (2003) Full-thickness thoracic laminar erosion after posterior spinal fusion associated with late-presenting infection. Spine (Phila Pa 1976) 28:E194–E197CrossRef Tribus CB, Garvey KE (2003) Full-thickness thoracic laminar erosion after posterior spinal fusion associated with late-presenting infection. Spine (Phila Pa 1976) 28:E194–E197CrossRef
20.
go back to reference Beguiristain J, Del Río J, Duart J, Barroso J, Silva A, Villas C (2006) Corrosion and late infection causing delayed paraparesis after spinal instrumentation. J Pediatr Orthop B 15:320–323PubMedCrossRef Beguiristain J, Del Río J, Duart J, Barroso J, Silva A, Villas C (2006) Corrosion and late infection causing delayed paraparesis after spinal instrumentation. J Pediatr Orthop B 15:320–323PubMedCrossRef
Metadata
Title
Propionibacterium acnes delayed infection following spinal surgery with instrumentation
Authors
Hani H. Mhaidli
Asdghig H. Der-Boghossian
Rachid K. Haidar
Publication date
01-04-2013
Publisher
Springer Milan
Published in
MUSCULOSKELETAL SURGERY / Issue 1/2013
Print ISSN: 2035-5106
Electronic ISSN: 2035-5114
DOI
https://doi.org/10.1007/s12306-012-0183-6

Other articles of this Issue 1/2013

MUSCULOSKELETAL SURGERY 1/2013 Go to the issue