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Indian Journal of Hematology and Blood Transfusion

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01-10-2020 | Hepatitis C | Short Communication

A Pilot Study to Assess Transfusion Transmission of Hepatitis C Virus

Authors: Ahmed El-Nawawy, Shams Abdel-Fattah Arafa, Adham Ahmed Badeib, Manal A.-M. Antonios

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 4/2020

Abstract

Alexandria University blood bank adopted double screening tests: a fully automated chemiluminescence immunoassay followed by nucleic acid testing. The aim of the study was to assess the efficiency of dual check of HCV in preventing transfusion related infection among patients admitted to PICU. A prospective cohort study was carried on patients admitted to PICU during 6 months. The included patients performed HCV RNA detection on admission by conventional reverse transcriptase polymerase chain reaction (RT-PCR) technique. Only negative cases were recruited, then patients receiving blood or its product were checked after 4 weeks from discharge by RT-PCR for HCV RNA. A total of 33 patients received 108 transfusions: 9 patients of them deceased during PICU stay and the remaining 24 patients were all found to be negative for HCV. The dual screening of HCV should be implemented in all blood banks of Egypt especially for critically ill pediatric patients.

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Title: A Pilot Study to Assess Transfusion Transmission of Hepatitis C Virus
Authors: Ahmed El-Nawawy
Shams Abdel-Fattah Arafa
Adham Ahmed Badeib
Manal A.-M. Antonios
Publication date: 01-10-2020
Publisher: Springer India
Keyword: Hepatitis C
Published in: Indian Journal of Hematology and Blood Transfusion / Issue 4/2020
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI: https://doi.org/10.1007/s12288-020-01265-0

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