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Indian Journal of Hematology and Blood Transfusion
Published in: Indian Journal of Hematology and Blood Transfusion 3/2019

01-07-2019 | Antiphospholipid Syndrome | Editorial

Plasma Coagulation Tests for Detection of Antiphospholipid Antibodies: What’s Good, and What Might Be Improved?

Authors: Sukesh Chandran Nair, Tulasi Geevar, Rutvi Gautam Dave

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 3/2019

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Excerpt

DRVVT is a test to detect Lupus anticoagulant (LA) as part for investigation for Antiphospholipid syndrome (APS) along with Anticardiolipin (aCL) and Anti-β2-glycoprotein-I (aβ2GPI) antibodies. …
Literature
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Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R et al (2006) International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 4(2):295–306CrossRefPubMed
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Tripodi A (2007) Laboratory testing for lupus anticoagulants: a review of issues affecting results. Clin Chem 53(9):1629–1635CrossRefPubMed
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Pengo V, Tripodi A, Reber G, Rand JH, Ortel TL, Galli M et al (2009) Update of the guidelines for lupus anticoagulant detection. J Thromb Haemost 7(10):1737–1740CrossRefPubMed
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Ramaraj A, Negi VS, Kar R (2019) Assessment of normative range and deriving cut-off values for lupus anticoagulant testing: an experience from a tertiary care center in Southern India. Indian J Hematol Blood Transfus 25:1–4
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Ahuja A, Tyagi S, Pati HP, Saxena R, Somasundaram V, Manivannan P et al (2019) Utility of lupus anticoagulant assays (APTT-LA, KCT, DPT and DRVVT) in detection of antiphospholipid syndrome (APS) in high risk pregnancy cases. Indian J Hematol Blood Transfus 23:1–7
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de Laat B, Pengo V, Pabinger I, Musial J, Voskuyl AE, Bultink IEM et al (2009) The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: an international multicenter study. J Thromb Haemost 7(11):1767–1773CrossRefPubMed
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Pengo V, Biasiolo A, Gresele P, Marongiu F, Erba N, Veschi F et al (2007) A comparison of lupus anticoagulant-positive patients with clinical picture of antiphospholipid syndrome and those without. Arterioscler Thromb Vasc Biol 27(12):e309–e310CrossRefPubMed
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de Laat HB, Derksen RHWM, Urbanus RT, Roest M, de Groot PG (2004) beta2-glycoprotein I-dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome. Blood 104(12):3598–3602CrossRefPubMed
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Pengo V, Biasiolo A, Pegoraro C, Iliceto S (2004) A two-step coagulation test to identify antiβ2-glycoprotein I lupus anticoagulants. J Thromb Haemost 2(5):702–707CrossRefPubMed
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Male C, Lechner K, Speiser W, Pabinger I (2000) Transient lupus anticoagulants in children: stepwise disappearance of diagnostic features. Thromb Haemost 83(1):174–175CrossRefPubMed
Metadata
Title
Plasma Coagulation Tests for Detection of Antiphospholipid Antibodies: What’s Good, and What Might Be Improved?
Authors
Sukesh Chandran Nair
Tulasi Geevar
Rutvi Gautam Dave
Publication date
01-07-2019
Publisher
Springer India
Published in
Indian Journal of Hematology and Blood Transfusion / Issue 3/2019
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-019-01151-4

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