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Indian Journal of Hematology and Blood Transfusion
Published in: Indian Journal of Hematology and Blood Transfusion 2/2017

01-06-2017 | Correspondence

Growth Factor Variation in Two Types of Autologous Platelet Biomaterials: PRP Versus PRF

Authors: Satyam Arora, Urvershi Kotwal, Mitu Dogra, Veena Doda

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 2/2017

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Abstract

Autologous platelet biomaterials represent a key source of cytokines and growth factors extensively used for clinical and surgical applications involving tissue regeneration; wound healing and tissue repair. In this communication we discuss the growth factors released by activated platelet rich plasma (PRP) and platelet rich fibrin (PRF) releasate. Our study highlights that significantly higher growth factors (TGF-ß1) are released by activated PRP as compared to releasate of PRF. The various growth factors released by both platelet products are significantly higher than the baseline concentration in the whole blood and have different bio-mechanism hence should be individualized as per the clinical indication.
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Metadata
Title
Growth Factor Variation in Two Types of Autologous Platelet Biomaterials: PRP Versus PRF
Authors
Satyam Arora
Urvershi Kotwal
Mitu Dogra
Veena Doda
Publication date
01-06-2017
Publisher
Springer India
Published in
Indian Journal of Hematology and Blood Transfusion / Issue 2/2017
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-016-0721-8

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