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Indian Journal of Hematology and Blood Transfusion

Published in:

01-03-2017 | Original Article

NK/T Cell Lymphoma: A Tertiary Centre Experience

Authors: Neeraj Arora, Arpan Mehta, Sriram Ravichandran, Indu Arun, Rimpa Basu Achari, Anupam Chakrapani, Saurabh Jayant Bhave, Mammen Chandy, Reena Nair

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 1/2017

Abstract

Extranodal NK/T-cell lymphoma (ENKTL), nasal type, is a rare type of non-Hodgkin lymphoma that is commonly seen in East Asian countries and is associated with Epstein-Barr virus infection. This is a retrospective study where we describe nine cases of ENKTL; nasal type diagnosed and treated at our center over a period of 2 years. These cases were analyzed retrospectively for clinical presentation (age, sex, site of involvement), immunophenotype, treatment, response and toxicity profile. Sino-nasal symptoms (blocked nose, headache, epistaxis, regurgitation) were the most common presenting complaints (n = 8). Almost 67 % (n = 6/9) of the cases were referred from Bhutan. Necrosis and angiocentricity were the commonest histological features. Depending on the stage of the disease patient were initially treated with chemotherapy (SMILE/CHOP) and Radiotherapy (IFRT). We describe our experience of management of ENKTL, where we observe that Bhutan could be endemic region for this rare tumour.

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Title: NK/T Cell Lymphoma: A Tertiary Centre Experience
Authors: Neeraj Arora
Arpan Mehta
Sriram Ravichandran
Indu Arun
Rimpa Basu Achari
Anupam Chakrapani
Saurabh Jayant Bhave
Mammen Chandy
Reena Nair
Publication date: 01-03-2017
Publisher: Springer India
Published in: Indian Journal of Hematology and Blood Transfusion / Issue 1/2017
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI: https://doi.org/10.1007/s12288-016-0675-x

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