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Neuroscience Bulletin
Published in: Neuroscience Bulletin 5/2017

01-10-2017 | Editorial

Biomarker Discovery in Parkinson’s Disease: Present Challenges and Future Opportunities

Authors: Song Li, Weidong Le

Published in: Neuroscience Bulletin | Issue 5/2017

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Excerpt

Parkinson’s disease (PD) is the second most common neurodegenerative disorder affecting more than 1% of the older population. Histopathologically, PD is characterized by a severe loss of dopaminergic neurons in the substantia nigra and cytoplasmic inclusions composed of insoluble protein aggregates (Lewy bodies), which lead to a progressive movement disorder including the classic triad of tremor, bradykinesia, and rigidity. …
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Zhong CB, Chen QQ, Haikal C, Li W, Svanbergsson A, Diepenbroek M, et al. Age-dependent alpha-synuclein accumulation and phosphorylation in the enteric nervous system in a transgenic mouse model of Parkinson’s disease. Neurosci Bull 2017, 33: 483–492.CrossRef
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Metadata
Title
Biomarker Discovery in Parkinson’s Disease: Present Challenges and Future Opportunities
Authors
Song Li
Weidong Le
Publication date
01-10-2017
Publisher
Springer Singapore
Published in
Neuroscience Bulletin / Issue 5/2017
Print ISSN: 1673-7067
Electronic ISSN: 1995-8218
DOI
https://doi.org/10.1007/s12264-017-0184-4

Other articles of this Issue 5/2017

Neuroscience Bulletin 5/2017 Go to the issue

Original Article

Age-Dependent Alpha-Synuclein Accumulation and Phosphorylation in the Enteric Nervous System in a Transgenic Mouse Model of Parkinson’s Disease

Review

Tiny But Mighty: Promising Roles of MicroRNAs in the Diagnosis and Treatment of Parkinson’s Disease

Review

Region-Specific Iron Measured by MRI as a Biomarker for Parkinson’s Disease

Report

Genetic Analysis of FBXO2, FBXO6, FBXO12, and FBXO41 Variants in Han Chinese Patients with Sporadic Parkinson’s Disease

Review

Cerebral Dopamine Neurotrophic Factor: A Potential Therapeutic Agent for Parkinson’s Disease

Research Highlight

Milestones of Parkinson’s Disease Research: 200 Years of History and Beyond